Clinical Director, Division of Allergy, Immunology and Pulmonary Medicine at St. Louis Children's Hospital and Professor, Pediatrics, Washington University School of Medicine
Allergy & Immunology
Dr. Leonard B. Bacharier, MD
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Leonard Bacharier works in the field of Allergy & Immunology. He researched medicine at Washington University School of Medicine in St. Louis. He over the years received 3 awards: "Fellow", "Regional Top Doctor" and "Fellow (FAAAAI)". Dr. Leonard B. Bacharier is a published doctor and has 84 publications published. The lastest was: 'Molecular mechanisms of immunoglobulin E regulation.'
Publications
- Early-life respiratory infections and asthma development: role in disease pathogenesis and potential targets for disease prevention.
- Temporal biological variability in dendritic cells and regulatory T cells in peripheral blood of healthy adults.
- Vitamin D3 treatment of vitamin D-insufficient asthmatic patients does not alter immune cell function.
- Early Administration of Azithromycin and Prevention of Severe Lower Respiratory Tract Illnesses in Preschool Children With a History of Such Illnesses: A Randomized Cl...
- Does azithromycin modify viral load during severe respiratory syncytial virus bronchiolitis?
- Markers of Differential Response to Inhaled Corticosteroid Treatment Among Children With Mild Persistent Asthma.
- Longitudinal changes in airway remodeling and air trapping in severe asthma.
- Effect of Vitamin D3 on Asthma Treatment Failures in Adults With Symptomatic Asthma and Lower Vitamin D Levels: The VIDA Randomized Clinical Trial.
- Effects of early-life exposure to allergens and bacteria on recurrent wheeze and atopy in urban children.
- Early-life weight gain, prematurity, and asthma development.
- The association between vitamin D status and the rate of exacerbations requiring oral corticosteroids in preschool children with recurrent wheezing.
- The relationships between environmental bacterial exposure, airway bacterial colonization, and asthma.
- The Vitamin D Antenatal Asthma Reduction Trial (VDAART): Rationale, design, and methods of a randomized, controlled trial of vitamin D supplementation in pregnancy for...
- The challenge of treating preschool wheezing episodes: The need for evidence-based approaches.
- Infection-induced wheezing in young children.
- Predictors of asthma control and lung function responsiveness to step 3 therapy in children with uncontrolled asthma.
- Vitamin D status at birth: An important and potentially modifiable determinant of atopic disease in childhood?
- Do oral corticosteroids reduce the severity of acute lower respiratory tract illnesses in preschool children with recurrent wheezing?
- The role of early life viral bronchiolitis in the inception of asthma.
- Clinical and laboratory factors associated with negative oral food challenges.
- Determinants of asthma after severe respiratory syncytial virus bronchiolitis.
- Severe asthma in childhood: recent advances in phenotyping and pathogenesis.
- Caregivers report a wide variety of early signs and symptoms of impending asthma exacerbations that are not different between preschool and school-aged children.
- Evaluation of the child with recurrent wheezing.
- Phenotypic expressions of childhood wheezing and asthma: implications for therapy.
- Controversies in the treatment of the acutely wheezing infant.
- Asthma endotypes: a new approach to classification of disease entities within the asthma syndrome.
- Socioeconomic status associated with exhaled nitric oxide responses to acute stress in children with asthma.
- Viral-induced wheezing episodes in preschool children: approaches to therapy.
- Diagnosis and management of asthma in preschool and school-age children: focus on the 2007 NAEPP Guidelines.
- Cytokine response after severe respiratory syncytial virus bronchiolitis in early life.
- Management of asthma in preschool children with inhaled corticosteroids and leukotriene receptor antagonists.
- Does exhaled nitric oxide measurement help distinguish between wheezing phenotypes in preschool children?
- Pediatric asthma admissions: chronic severity and acute exacerbations.
- Management approaches to intermittent wheezing in young children.
- Long-term inhaled corticosteroids in preschool children at high risk for asthma.
- The atopic march: the pattern of allergic disease development in childhood.
- Infectious triggers of asthma.
- Characterization of within-subject responses to fluticasone and montelukast in childhood asthma.
- Severity of respiratory syncytial virus bronchiolitis is affected by cigarette smoke exposure and atopy.
- Atopic characteristics of children with recurrent wheezing at high risk for the development of childhood asthma.
- Classifying asthma severity in children: mismatch between symptoms, medication use, and lung function.
- Long-term effect of budesonide on hypothalamic-pituitary-adrenal axis function in children with mild to moderate asthma.
- Are the results of oral food challenges predictable?
- Socioeconomic status, stress, and immune markers in adolescents with asthma.
- Pets and childhood asthma--how should the pediatrician respond to new information that pets may prevent asthma?
- C4b-binding protein (C4BP) activates B cells through the CD40 receptor.
- Nocturnal awakening caused by asthma in children with mild-to-moderate asthma in the childhood asthma management program.
- "Step-down" therapy for asthma: why, when, and how?
- Pooled Sequencing of Candidate Genes Implicates Rare Variants in the Development of Asthma Following Severe RSV Bronchiolitis in Infancy.
- Intraoperative anaphylaxis secondary to intraosseous gelatin administration.
- Nonrespiratory symptoms before loss of asthma control in children.
- Severe intermittent wheezing in preschool children: a distinct phenotype.
- Daily or intermittent budesonide in preschool children with recurrent wheezing.
- Step-down therapy in asthma: A focus on treatment options for patients receiving inhaled corticosteroids and long-acting beta-agonist combination therapy.
- Growth of preschool children at high risk for asthma 2 years after discontinuation of fluticasone.
- Most nocturnal asthma symptoms occur outside of exacerbations and associate with morbidity.
- Use of beclomethasone dipropionate as rescue treatment for children with mild persistent asthma (TREXA): a randomised, double-blind, placebo-controlled trial.
- Step-up therapy for children with uncontrolled asthma receiving inhaled corticosteroids.
- Forced expiratory flow between 25% and 75% of vital capacity and FEV1/forced vital capacity ratio in relation to clinical and physiological parameters in asthmatic chi...
- Urinary leukotriene E4/exhaled nitric oxide ratio and montelukast response in childhood asthma.
- Heterogeneity of severe asthma in childhood: confirmation by cluster analysis of children in the National Institutes of Health/National Heart, Lung, and Blood Institut...
- Phenotypic predictors of long-term response to inhaled corticosteroid and leukotriene modifier therapies in pediatric asthma.
- Lower levels of plasmacytoid dendritic cells in peripheral blood are associated with a diagnosis of asthma 6 yr after severe respiratory syncytial virus bronchiolitis.
- Patient characteristics associated with improved outcomes with use of an inhaled corticosteroid in preschool children at risk for asthma.
- Signs and symptoms that precede wheezing in children with a pattern of moderate-to-severe intermittent wheezing.
- Relationship between infant weight gain and later asthma.
- Effect of elevated exhaled nitric oxide levels on the risk of respiratory tract illness in preschool-aged children with moderate-to-severe intermittent wheezing.
- Azithromycin or montelukast as inhaled corticosteroid-sparing agents in moderate-to-severe childhood asthma study.
- Episodic use of an inhaled corticosteroid or leukotriene receptor antagonist in preschool children with moderate-to-severe intermittent wheezing.
- Impulse oscillometry versus spirometry in a long-term study of controller therapy for pediatric asthma.
- Long-term comparison of 3 controller regimens for mild-moderate persistent childhood asthma: the Pediatric Asthma Controller Trial.
- The Prevention of Early Asthma in Kids study: design, rationale and methods for the Childhood Asthma Research and Education network.
- Response profiles to fluticasone and montelukast in mild-to-moderate persistent childhood asthma.
- Hospitalization for asthma: atopic, pulmonary function, and psychological correlates among participants in the Childhood Asthma Management Program.
- Molecular mechanisms of immunoglobulin E regulation.
- Regulation of IgE synthesis: the molecular basis and implications for clinical modulation.
- Ku in the cytoplasm associates with CD40 in human B cells and translocates into the nucleus following incubation with IL-4 and anti-CD40 mAb.
- Molecular mechanisms of IgE regulation.
- Diagnosis and treatment of asthma in childhood: a PRACTALL consensus report.
- Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute''s Severe Asthma Research Program.
- Natural history of asthma: persistence versus progression-does the beginning predict the end?
- Vitamin D3 therapy in patients with asthma complicated by sinonasal disease: Secondary analysis of the Vitamin D Add-on Therapy Enhances Corticosteroid Responsiveness ...
Schools
Washington Center School of Medicine
St Louis Chldns Hospital
Children39s Hospital Boston
Doctors Specialties
- Pediatrics
- Allergy
- Immunology
Accepted Insurances
Awards
- Fellow
- Regional Top Doctor
- Fellow (FAAAAI)
Education
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Boston Children's Hospital -
Washington University School of Medicine in St. Louis
Hospital
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St. Louis Children's Hospital
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