Physician
Radiology
Dr. Liang Gu, MD
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Liang practices Radiology. He went to Medical College of Georgia School of Medicine. Liang Gu is a published doctor. He has 66 papers published. The most current publication "Disubstituted quinazoline derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA." He accepts Medicare.
Publications
- Mycobacterium tuberculosis Hsp16.3 nonamers are assembled and re-assembled via trimer and hexamer intermediates.
- [Solubilization on cryptotanshinone by hydroxypropyl-beta-cyclodextrin and preparation of their inclusion compound].
- G-quadruplex ligand SYUIQ-5 induces autophagy by telomere damage and TRF2 delocalization in cancer cells.
- Screening novel, potent multidrug-resistant modulators from imidazole derivatives.
- Synthesis and cytotoxicity study of alkannin derivatives.
- Curcumin analogs as potent aldose reductase inhibitors.
- High performance liquid chromatography with ultraviolet detection for the determination of SYUIQ-5, a novel telomerase inhibitor for cancer therapy: application to an ...
- Spectroscopic studies of DNA binding modes of cation-substituted anthrapyrazoles derived from emodin.
- Apoptosis-inducing activity of new pyrazole emodin derivatives in human hepatocellular carcinoma HepG2 cells.
- Isaindigotone derivatives: a new class of highly selective ligands for telomeric G-quadruplex DNA.
- Synthesis, biological evaluation and molecular modeling of oxoisoaporphine and oxoaporphine derivatives as new dual inhibitors of acetylcholinesterase/butyrylcholinest...
- Inhibition of thioredoxin reductase by mansonone F analogues: Implications for anticancer activity.
- Inhibition of thioredoxin reductase by curcumin analogs.
- Synthesis, cytotoxic activities and structure-activity relationships of topoisomerase I inhibitors: indolizinoquinoline-5,12-dione derivatives.
- Solvent-free thermocyclization of the unactivated linear gramicidin S precursor and analogues.
- Studies on the binding of 5-N-methylated quindoline derivative to human telomeric G-quadruplex.
- Synthesis and biological evaluation of novel N,N''-bis-methylenedioxybenzyl-alkylenediamines as bivalent anti-Alzheimer disease ligands.
- New insights into the structures of ligand-quadruplex complexes from molecular dynamics simulations.
- Selective recognition of oncogene promoter G-quadruplexes by Mg2+.
- Icariin derivative inhibits inflammation through suppression of p38 mitogen-activated protein kinase and nuclear factor-kappaB pathways.
- Synthesis and evaluation of graveoline and graveolinine derivatives with potent anti-angiogenesis activities.
- Turning off transcription of the bcl-2 gene by stabilizing the bcl-2 promoter quadruplex with quindoline derivatives.
- Synthesis, antimicrobial activity and possible mechanism of action of 9-bromo-substituted indolizinoquinoline-5,12-dione derivatives.
- Impact of planarity of unfused aromatic molecules on G-quadruplex binding: learning from isaindigotone derivatives.
- Inhibition of cell proliferation by quindoline derivative (SYUIQ-05) through its preferential interaction with c-myc promoter G-quadruplex.
- Synthesis and evaluation of heterobivalent tacrine derivatives as potential multi-functional anti-Alzheimer agents.
- Disubstituted quinazoline derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA.
- Design, synthesis, and biological evaluation of curcumin analogues as multifunctional agents for the treatment of Alzheimer''s disease.
- Synthesis and evaluation of novel rutaecarpine derivatives and related alkaloids derivatives as selective acetylcholinesterase inhibitors.
- Disubstituted 2-phenyl-benzopyranopyrimidine derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA.
- Syntheses and characterization of novel oxoisoaporphine derivatives as dual inhibitors for cholinesterases and amyloid beta aggregation.
- Syntheses and characterization of nimesulide derivatives for dual enzyme inhibitors of both cyclooxygenase-1/2 and 5-lipoxygenase.
- Effective detection and separation method for G-quadruplex DNA based on its specific precipitation with Mg(2+).
- Pharmacophore-based discovery of triaryl-substituted imidazole as new telomeric G-quadruplex ligand.
- G-quadruplexes: targets in anticancer drug design.
- 9-N-Substituted berberine derivatives: stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc.
- Design, synthesis and evaluation of isaindigotone derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors.
- Synthesis and antimultidrug resistance evaluation of icariin and its derivatives.
- Synthesis and evaluation of 9-O-substituted berberine derivatives containing aza-aromatic terminal group as highly selective telomeric G-quadruplex stabilizing ligands.
- 5-N-methylated quindoline derivatives as telomeric g-quadruplex stabilizing ligands: effects of 5-N positive charge on quadruplex binding affinity and cell proliferation.
- Derivatives of oxoisoaporphine alkaloids: a novel class of selective acetylcholinesterase inhibitors.
- Stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc by quindoline derivatives.
- Synthesis of zwitterionic 4-hydroxycoumarin derivatives through a unique reaction of 4-hydroxycoumarins with p- benzoquinone and pyridine.
- Synthesis and evaluation of quindoline derivatives as G-quadruplex inducing and stabilizing ligands and potential inhibitors of telomerase.
- Covalent immobilization of carbohydrates on sol-gel-coated microplates.
- 9-Substituted berberine derivatives as G-quadruplex stabilizing ligands in telomeric DNA.
- Biotransformation and pharmacokinetics of the novel anticancer drug, SYUIQ-5, in the rat.
- A novel DNA topoisomerase I inhibitor with different mechanism from camptothecin induces G2/M phase cell cycle arrest to K562 cells.
- Synthesis and antibacterial activity of a series of alpha-substituted acetylpiperazinyl oxazolidinones.
- Synthesis and antibacterial activities of eperezolid analogs with glycinyl substitutions.
- Synthesis and antiproliferative activity of indolizinophthalazine-5,12-dione derivatives, DNA topoisomerase IB inhibitors.
- Oxoisoaporphine alkaloid derivatives: synthesis, DNA binding affinity and cytotoxicity.
- Alpha-glucosidase inhibition of natural curcuminoids and curcumin analogs.
- The molecular mechanisms involved in the cytotoxicity of alkannin derivatives.
- Design, synthesis and evaluation of novel tacrine-multialkoxybenzene hybrids as dual inhibitors for cholinesterases and amyloid beta aggregation.
- Bisaryldiketene derivatives: A new class of selective ligands for c-myc G-quadruplex DNA.
- Blockade of Her2/neu binding to Hsp90 by emodin azide methyl anthraquinone derivative induces proteasomal degradation of Her2/neu.
- Quinolino-benzo-[5, 6]-dihydroisoquindolium compounds derived from berberine: a new class of highly selective ligands for G-quadruplex DNA in c-myc oncogene.
- [Apoptosis of human carcinoma of mouth floor KB cells and multidrug resistant KBv200 cells induced by azide methyl anthraquinone derivative].
- [Synthesis and antitumour activities of some pteridine derivatives].
- Synthesis and evaluation of mansonone F derivatives as topoisomerase inhibitors.
- Synthesis and evaluation of curcumin analogues as potential thioredoxin reductase inhibitors.
- [Enhancement of FG020326 on sensitivity of MCF-7/ADR cells to taxotere via enhancing activation of caspase-8 and caspase-3].
- Reversal of P-gp mediated multidrug resistance in-vitro and in-vivo by FG020318.
- Cytotoxic diterpenoids from the soft coral Sinularia microclavata.
Schools
Medical College of Georgia
Doctors Specialties
- Diagnostic Radiology
- Radiology
Accepted Insurances
Education
-
Emory University -
Medical College of Georgia School of Medicine
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1427232966 |
| Last Name Of The Provider | GU |
| First Name Of The Provider | LIANG |
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