Professor, Pathology, Ohio State University College of Medicine
Medical Genetics
Dr. Lynne V. Abruzzo, MD
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Lynne Abruzzo works in the field of Medical Genetics. She graduated from University of Chicago Pritzker School of Medicine. University of Chicago Pritzker School of Medicine is ranked 10 in research and 19 in primary care medicine Lynne Abruzzo is a published doctor and has 79 publications published. The lastest was: 'Externally validated predictive clinical model for untreated del(17p13.1) chronic lymphocytic leukemia patients.'
Publications
- Externally validated predictive clinical model for untreated del(17p13.1) chronic lymphocytic Leukemia patients.
- High fluorescence in situ hybridization percentage of deletion 11q in patients with chronic lymphocytic Leukemia is an independent predictor of adverse outcome.
- Second Cancers and Richter Transformation Are the Leading Causes of Death in Patients With Trisomy 12 Chronic Lymphocytic Leukemia.
- Isolated mesenteric CD20-positive Myeloid sarcoma.
- Alopecia areata after HLA-identical BMT from an affected, sibling donor.
- Prognostic Implications of Chromosome 17 Abnormalities in the Context of Monosomal Karyotype in Patients With Acute Myeloid Leukemia and Complex Cytogenetics.
- HCVAD plus imatinib or dasatinib in lymphoid blastic phase chronic myeloid Leukemia.
- CD4(-)/CD8(-) Variant of T-Cell Large Granular Lymphocytic Leukemia or Hepatosplenic T-Cell Lymphoma: A Clinicopathologic Dilemma.
- Sequential lymphomas or clonally unrelated richter syndrome of chronic lymphocytic Leukemia into mantle cell lymphoma.
- Acquisition of cytogenetic abnormalities in patients with IPSS defined lower-risk Myelodysplastic syndrome is associated with poor prognosis and transformation to acut...
- DEAR1 Is a Chromosome 1p35 Tumor Suppressor and Master Regulator of TGF-β-Driven Epithelial-Mesenchymal Transition.
- B Acute lymphoblastic leukemia with t(14;19)(q32;p13.1) involving IGH/EPOR: a clinically aggressive subset of disease.
- Plasma Cell enrichment enhances detection of high-risk cytogenomic abnormalities by fluorescence in situ hybridization and improves risk stratification of patients wit...
- Chronic lymphocytic Leukemia with t(14;18)(q32;q21).
- Chromosome 5q deletion is extremely rare in patients with myelofibrosis.
- Rapid generation of human B-cell Lymphomas via combined expression of Myc and Bcl2 and their use as a preclinical model for biological therapies.
- Genomic Variation by Whole-Genome SNP Mapping Arrays Predicts Time-to-Event Outcome in Patients with Chronic Lymphocytic Leukemia: A Comparison of CLL and HapMap Genot...
- Prognostic significance of 11q23 aberrations in adult Acute myeloid leukemia and the role of allogeneic stem cell transplantation.
- Mutational profile and prognostic significance of TP53 in diffuse large B-cell Lymphoma patients treated with rituximab-CHOP: a report from an International DLBCL Ritu...
- The prognostic difference of monoallelic versus biallelic deletion of 13q in chronic lymphocytic Leukemia.
- Relax with CouchDB - Into the non-relational DBMS era of Bioinformatics.
- Th17 and non-Th17 IL-17-expressing cells in chronic lymphocytic Leukemia: delineation, distribution, and clinical relevance.
- Array comparative genomic hybridization analysis identifies recurrent gain of chromosome 2p25.3 involving the ACP1 and MYCN genes in chronic lymphocytic Leukemia.
- The B cell antigen receptor in atypical chronic lymphocytic Leukemia with t(14;19)(q32;q13) demonstrates remarkable stereotypy.
- Chronic lymphocytic Leukemia with t(14;19)(q32;q13) is characterized by atypical morphologic and immunophenotypic features and distinctive genetic features.
- Prognostic impact of deletions of derivative chromosome 9 in patients with chronic myelogenous Leukemia treated with nilotinib or dasatinib.
- LDOC1 mRNA is differentially expressed in chronic lymphocytic Leukemia and predicts overall survival in untreated patients.
- A Two-Gene Signature, SKI and SLAMF1, Predicts Time-to-Treatment in Previously Untreated Patients with Chronic Lymphocytic Leukemia.
- Immunohistochemical detection of ZAP70 in chronic lymphocytic Leukemia predicts immunoglobulin heavy chain gene mutation status and time to progression.
- A pathway-based gene signature correlates with therapeutic response in adult patients with Philadelphia chromosome-positive Acute lymphoblastic leukemia.
- Differential expression of CKS-1B in typical and blastoid variants of mantle cell Lymphoma.
- microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival.
- Myelodysplastic syndromes arising in patients with germline TP53 mutation and Li-Fraumeni syndrome.
- Acute erythroid leukemia: a reassessment using criteria refined in the 2008 WHO classification.
- Chronic myeloid Leukemia in blast phase associated with t(3;8)(q26;q24).
- De novo deletion 17p13.1 chronic lymphocytic Leukemia shows significant clinical heterogeneity: the M. D. Anderson and Mayo Clinic experience.
- del(15q) is a recurrent minor-route cytogenetic abnormality in the clonal evolution of chronic myelogenous Leukemia.
- Therapy-related Acute myeloid leukemia with t(8;21) (q22;q22) shares many features with de novo Acute myeloid leukemia with t(8;21)(q22;q22) but does not have a favora...
- Chronic lymphocytic Leukemia With t(2;14)(p16;q32) involves the BCL11A and IgH genes and is associated with atypical morphologic features and unmutated IgVH genes.
- The role of cytogenetic abnormalities as a prognostic marker in primary myelofibrosis: applicability at the time of diagnosis and later during Disease course.
- Relevance of the immunoglobulin VH somatic mutation status in patients with chronic lymphocytic Leukemia treated with fludarabine, cyclophosphamide, and rituximab (FCR...
- Deletion 15q as the sole abnormality in Acute myeloid leukemia: report of three cases and review of the literature.
- Chemoimmunotherapy may overcome the adverse prognostic significance of 11q deletion in previously untreated patients with chronic lymphocytic Leukemia.
- Customized oligonucleotide array-based comparative genomic hybridization as a clinical assay for genomic profiling of chronic lymphocytic Leukemia.
- Fluorescence in situ hybridization is a useful ancillary diagnostic tool for extraskeletal myxoid chondrosarcoma.
- Translocation (18;22)(q21;q11) in B-cell Lymphomas: a report of 4 cases and review of the literature.
- Whole-genome scanning by array comparative genomic hybridization as a clinical tool for risk assessment in chronic lymphocytic Leukemia.
- Dermatofibrosarcoma protuberans COL1A1-PDGFB fusion is identified in virtually all dermatofibrosarcoma protuberans cases when investigated by newly developed multiplex...
- t(8;13)-positive bilineal Lymphomas: report of 6 cases.
- Breast Lymphoma: imaging findings of 32 tumors in 27 patients.
- Chromosomal abnormalities in Philadelphia chromosome negative metaphases appearing during imatinib mesylate therapy in patients with newly diagnosed Chronic myeloid le...
- Identification and validation of biomarkers of IgV(H) mutation status in chronic lymphocytic Leukemia using microfluidics quantitative real-time polymerase chain react...
- MALT Lymphoma involving the kidney: a report of 10 cases and review of the literature.
- Aberrant EVI1 expression in Acute myeloid leukemias associated with the t(3;8)(q26;q24).
- Sequence analysis proves clonal identity in five patients with typical and blastoid mantle cell Lymphoma.
- MALT1 gene rearrangements and NF-kappaB activation involving p65 and p50 are absent or rare in primary MALT Lymphomas of the breast.
- Myelodysplastic syndromes and Acute leukemia developing after imatinib mesylate therapy for chronic myeloid leukemia.
- Molecular diagnosis of sarcomas: chromosomal translocations in sarcomas.
- Myeloid sarcoma of the urinary bladder and epididymis as a primary manifestation of Acute myeloid leukemia with inv(16).
- Translocation (3;8)(q26;q24): a recurrent chromosomal abnormality in myelodysplastic syndrome and Acute myeloid leukemia.
- Acute myeloid leukemia associated with variant t(8;21) detected by conventional cytogenetic and molecular studies: a report of four cases and review of the literature.
- Lymphoid neoplasms associated with concurrent t(14;18) and 8q24/c-MYC translocation generally have a poor prognosis.
- Chronic myeloproliferative diseases with the t(5;12)(q33;p13): clonal evolution is associated with blast crisis.
- Rosai-Dorfman Disease of the breast.
- Biological validation of differentially expressed genes in chronic lymphocytic Leukemia identified by applying multiple statistical methods to oligonucleotide microarr...
- Validation of oligonucleotide microarray data using microfluidic low-density arrays: a new statistical method to normalize real-time RT-PCR data.
- EBV-associated B- and T-Cell posttransplant lymphoproliferative disorders following primary EBV infection in a kidney transplant recipient.
- Immunohistochemical detection of ZAP-70 in 341 cases of non-Hodgkin and Hodgkin Lymphoma.
- Bone marrow involvement in patients with nodular lymphocyte predominant Hodgkin Lymphoma.
- Cytogenetic findings in blastoid mantle cell Lymphoma.
- Epidermal growth factor receptor expression in follicular dendritic cells: a shared feature of follicular dendritic cell sarcoma and Castleman's Disease.
- A pilot study of rituximab in patients with recurrent, classic Hodgkin Disease.
- High expression of activation-induced cytidine deaminase (AID) and splice variants is a distinctive feature of poor-prognosis chronic lymphocytic Leukemia.
- Novel translocation in Acute megakaryoblastic leukemia (AML-M7).
- Mantle cell lymphoma involving skin: cutaneous lesions may be the first manifestation of Disease and tumors often have blastoid cytologic features.
- Cutaneous and systemic plasmacytosis in a patient of Asian descent living in the United States.
- Epstein-Barr virus-positive B-Cell lymphoproliferative disorders arising in immunodeficient patients previously treated with fludarabine for low-grade B-Cell neoplasms.
- Identifying and quantifying sources of variation in microarray data using high-density cDNA membrane arrays.
Schools
U Of Chgo Div Of Bio Sci Pritzker Sch Of Med
University Of Mi Hosps and Health Ctrs
Conditions Treated
- Acute Leukemia
- Anemia
- Chronic Myeloid Leukemia (CML)
- Hodgkin's Disease
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Doctors Specialties
- Hematology
- Hematopathology
- Medical Genetics
Accepted Insurances
Education
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University of Michigan Hospitals and Health Centers -
University of Chicago Pritzker School of Medicine
Hospital
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University of Texas M.D. Anderson Cancer Center -
Ohio State University Wexner Medical Center
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1275647364 |
| Last Name Of The Provider | ABRUZZO |
| First Name Of The Provider | LYNNE |
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