Associate Professor, Neurological Surgery, UCSF School of Medicine
Neurosurgery
Dr. Manish K. Aghi, MD
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Manish Aghi works in the field of Neurosurgery. He attended Harvard Medical School. Harvard Medical School is a top medical college. Harvard Medical School is ranked 1 in research and 12 in primary care medicine He received awards:"CMS Meaningful Use Stage 1 Certification", "[415] Top Doctors", "Harold Rosegay Teaching Award", "Young Investigator Award", "Travel Grant Award", "Synthes Skull Base Award, for highest ranking abstract focused on skull base tumors", "Mahaley Award, for investigator presenting the best clinical study in neuro-oncology", "Integra Foundation Award, for highest ranking abstract focused on basic science or clinical research of benign brain and peripheral nerve tumors", "Ronald L. Bittner Award - best brain tumor research by a resident or junior faculty member", "William Scoville Resident Award - Best Paper", "Resident research award", "Annual Resident Award", "Preuss Award - best basic science research", "Resident Research Award, Honorable Mention", "James Andrew Smith Scholar for brain tumor research,", "Firestone Medal for Excellence in Undergraduate Research", "Norman K. Wessels Award for top biological sciences teaching assistant" and "Fellow (FAANS)". Manish Aghi has written publications. He has 99 publications published with PubMed. The lastest paper is: 'Preventing Delays in First-Case Starts on the Neurosurgery Service: A Resident-Led Initiative at an Academic Institution.' Manish Aghi accepts Medicare payments and is listed with Medicare.gov.
Publications
- The role of surgery in the management of patients with diffuse low grade glioma : A Systematic review and evidence-based clinical practice guideline.
- Approach to the postoperative patient with Cushing's Disease.
- Sinonasal morbidity following endoscopic endonasal skull base surgery.
- Convection-enhanced delivery for the treatment of glioblastoma.
- Cushing's Disease: current medical therapies and molecular insights guiding future therapies.
- Factors predicting recurrence after resection of clival Chordoma using variable surgical approaches and radiation modalities.
- Incidence of headache as a presenting complaint in over 1000 patients with sellar lesions and factors predicting postoperative improvement.
- HIGD1A Regulates Oxygen Consumption, ROS Production, and AMPK Activity during Glucose Deprivation to Modulate Cell Survival and Tumor Growth.
- A predictive algorithm for evaluating elevated serum prolactin in patients with a sellar mass.
- Risk factors for postoperative Cerebrospinal fluid leak and meningitis after expanded endoscopic endonasal surgery.
- Hypophysitis: a single-center case series.
- Molecularly targeted therapies for recurrent glioblastoma: current and future targets.
- Epidermal growth factor-like module containing mucin-like hormone receptor 2 expression in Gliomas.
- Optimizing glioblastoma resection: intraoperative mapping and beyond.
- Rate and time course of improvement in endocrine function after more than 1000 pituitary operations.
- GanglioGliomas of the optic pathway.
- Awards, lectures, and fellowships sponsored by the AANS/CNS Section on Tumors.
- Risk Factors for Cerebrospinal Leak after Endoscopic Skull Base Reconstruction with Nasoseptal Flap.
- Extended endoscopic endonasal approach for suprasellar Rathke's cleft cysts.
- Pituicytomas and spindle cell oncocytomas: modern case series from the University of California, San Francisco.
- Morbidity of repeat transsphenoidal surgery assessed in more than 1000 operations.
- Outcomes and patterns of care in adult skull base Chordomas from the Surveillance, Epidemiology, and End Results (SEER) database.
- Outcomes and patterns of care in adult skull base chondrosarcomas from the SEER database.
- Impact of platybasia and anatomic variance on surgical approaches to the craniovertebral junction.
- Tumors of the anterior skull base.
- β1 Integrin: Critical Path to Antiangiogenic Therapy Resistance and Beyond.
- Cavernous and inferior petrosal sinus sampling and dynamic magnetic resonance imaging in the preoperative evaluation of Cushing's Disease.
- Getting more out of radiation therapy in glioblastoma.
- Heat-shock protein peptide complex-96 vaccination for recurrent glioblastoma: a phase II, single-arm trial.
- Factors predicting postoperative hyponatremia and efficacy of hyponatremia management strategies after more than 1000 pituitary operations.
- Rathke's cleft cysts: review of natural history and surgical outcomes.
- Identification of pY654-β-catenin as a critical co-factor in hypoxia-inducible factor-1α signaling and tumor responses to hypoxia.
- Headache and Focal Neurologic Deficits in a 37-Year-Old Woman.
- Socioeconomic factors associated with pituitary apoplexy.
- Disseminated progression of glioblastoma after treatment with bevacizumab.
- β1 Integrin Targeting Potentiates Antiangiogenic Therapy and Inhibits the Growth of Bevacizumab-Resistant Glioblastoma.
- A Comprehensive Long-Term Retrospective Analysis of Silent Corticotrophic Adenomas versus Hormone-Negative Adenomas.
- Endoscopic surgery for tuberculum sellae meningiomas: a Systematic review and meta-analysis.
- Surgical outcomes in choroid plexus papillomas: an institutional experience.
- The prognostic implications of Hyam's subtype for patients with Kadish stage C esthesioneuroblastoma.
- Gene expression profile identifies tyrosine kinase c-Met as a targetable mediator of anti-angiogenic therapy resistance.
- Minimally invasive approaches to the anterior skull base.
- Skull base Chordomas: clinical features, prognostic factors, and therapeutics.
- Impact of extent of resection for recurrent glioblastoma on overall survival: clinical article.
- Clinical management of pituitary carcinomas.
- Medical versus surgical management of prolactinomas.
- VEGF Inhibits Tumor Cell Invasion and Mesenchymal Transition through a MET/VEGFR2 Complex.
- Regional variation in histopathologic features of tumor specimens from treatment-naive glioblastoma correlates with anatomic and physiologic MR Imaging.
- Hypoxia-induced tumor cell autophagy mediates resistance to anti-angiogenic therapy.
- Pseudoprogression and treatment effect.
- Hypoxia-induced autophagy promotes tumor cell survival and adaptation to antiangiogenic treatment in glioblastoma.
- Oncolytic herpes simplex virus engineering and preparation.
- Biomarkers predicting tumor response and evasion to anti-angiogenic therapy.
- Neurosurgical management and prognosis of patients with glioblastoma that progress during bevacizumab treatment.
- A critical evaluation of cystic features in primary glioblastoma as a prognostic factor for survival.
- Determinants of initial bone graft volume loss in posterolateral lumbar fusion.
- Factors associated with delay to pituitary adenoma diagnosis in patients with visual loss.
- Rathke cleft cysts in pediatric patients: presentation, surgical management, and postoperative outcomes.
- Suprasellar Rathke cleft cysts: clinical presentation and treatment outcomes.
- Application of Novel Response/Progression Measures for Surgically Delivered Therapies for Gliomas.
- Dopamine agonist-resistant prolactinomas.
- Excess mortality for patients with residual Disease following resection of pituitary adenomas.
- Impact of bevacizumab chemotherapy on craniotomy wound healing.
- Radiation treatment strategies for acromegaly.
- Reconstruction of dural defects of the endonasal skull base.
- Infected Rathke cleft cysts: distinguishing factors and factors predicting recurrence.
- Mechanisms of evasion to antiangiogenic therapy in glioblastoma.
- Biology of angiogenesis and invasion in glioma.
- Decreased rate of infection in glioblastoma patients with allelic loss of chromosome 10q.
- Long-term recurrence rates of atypical Meningiomas after gross total resection with or without postoperative adjuvant radiation.
- Phase ib trial of oncolytic herpes virus G207 shows safety of multiple injections and documents viral replication.
- Hypoxia enhances the replication of oncolytic herpes simplex virus.
- Management of recurrent and refractory Cushing's Disease with reoperation and/or proton beam radiosurgery.
- Increased prevalence of obesity and obesity-related postoperative complications in male patients with Meningiomas.
- Increased prevalence of obesity and obesity-related postoperative complications in male meningioma patients.
- Gliosarcoma arising from an oligodendroglioma (oligosarcoma).
- Preventing Delays in First-Case Starts on the Neurosurgery Service: A Resident-Led Initiative at an Academic Institution.
- Nuclear Localization of the Mitochondrial Factor HIGD1A during Metabolic Stress.
- New advances that enable identification of glioblastoma recurrence.
- Management of recurrent and refractory Cushing Disease.
- Oncolytic herpes simplex virus mutants exhibit enhanced replication in glioma cells evading temozolomide chemotherapy through deoxyribonucleic acid repair.
- Bone involvement predicts poor outcome in atypical meningioma.
- Human glioblastoma-derived Cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors.
- Effect of chemotherapy-induced DNA repair on oncolytic herpes simplex viral replication.
- Oncolytic herpes virus with defective ICP6 specifically replicates in quiescent cells with homozygous genetic mutations in p16.
- Angiogenic response caused by oncolytic herpes simplex virus-induced reduced thrombospondin expression can be prevented by specific viral mutations or by administering...
- Unilateral vestibular Schwannoma with other neurofibromatosis type 2-related tumors: clinical and molecular study of a unique phenotype.
- Viral vectors as therapeutic agents for glioblastoma.
- Oncolytic viral therapies - the clinical experience.
- Gene therapy for glioblastoma.
- Multimodal Cancer treatment mediated by a replicating oncolytic virus that delivers the oxazaphosphorine/rat cytochrome P450 2B1 and ganciclovir/herpes simplex virus t...
- Contribution of bone marrow-derived cells to blood vessels in ischemic tissues and tumors.
- Magnetic resonance imaging characteristics predict epidermal growth factor receptor amplification status in glioblastoma.
- Benign adult Brain tumors: an evidence-based medicine review.
- Interval, acute onset airway obstruction associated with a fracture of the C4 vertebra in a patient with ankylosing spondylitis.
- FACT-MNG: tumor site specific web-based outcome instrument for meningioma patients.
- Integration of preoperative anatomic and metabolic physiologic imaging of newly diagnosed glioma.
- Tumor stromal-derived factor-1 recruits vascular progenitors to mitotic neovasculature, where microenvironment influences their differentiated phenotypes.
Schools
Harvard Medical School
Procedures Preformed
- Cerebrospinal Fluid (CSF) Shunt - Insertion, Repair or Removal
- Craniectomy, Craniotomy, Surgery of Skull Base, Neuroendoscopy
- Lamina Procedures (incl. Laminectomy, Laminoplasty, Laminotomy)
- Nerve Block, Somatic
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Conditions Treated
- Brain and Nervous System Cancer (incl. Gliomas, Astrocytoma, Schwannoma, Medulloblastoma, Chordoma)
- Brain Aneurysm
- Brain Cancer
- Cerebral Artery Thrombosis
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Doctors Specialties
- Neurosurgery
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
- [415] Top Doctors
- Harold Rosegay Teaching Award
- Young Investigator Award
- Travel Grant Award
- Synthes Skull Base Award, for highest ranking abstract focused on skull base tumors
- Mahaley Award, for investigator presenting the best clinical study in neuro-oncology
- Integra Foundation Award, for highest ranking abstract focused on basic science or clinical research of benign brain and peripheral nerve tumors
- Ronald L. Bittner Award - best brain tumor research by a resident or junior faculty member
- William Scoville Resident Award - Best Paper
- Resident research award
- Annual Resident Award
- Preuss Award - best basic science research
- Resident Research Award, Honorable Mention
- James Andrew Smith Scholar for brain tumor research,
- Firestone Medal for Excellence in Undergraduate Research
- Norman K. Wessels Award for top biological sciences teaching assistant
- Fellow (FAANS)
Education
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Massachusetts General Hospital -
Harvard Medical School -
Harvard University -
Stanford University
Hospital
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UCSF Medical Center
Drug Facts
| NPI NUMBER | 1689647778 | |
| NPPES Provider LastName | AGHI | |
| NPPES Provider FirstName | MANISH | |
| NPPES Provider ZIPCode | 941430001 | |
| NPPES Provider State | CA | |
| Specialty Description | Neurosurgery | |
| Total Claim Count | 140.0 | |
| Distinct Opioid Count | 1.0 | |
| Opioid Claim Count | 16.0 | |
| Percent Opioid Claims | 11.43 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1689647778 |
| Last Name Of The Provider | AGHI |
| First Name Of The Provider | MANISH |
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