Managing Partner, Salutramed Group, Inc
Oncology
Dr. Margaret K. Offermann, MD
Margaret K. Offermann, MD works in the field of Oncology. She studied medicine at Virginia Commonwealth University School of Medicine. She received 8 awards: "President", "Executive Committee", "Alpha Omega Alpha Medical Honor Society", "Commencement Speaker, Bryan University Program in Applied Healthcare Informatics", "Board of Directors", "Charlotte Haywood Endowed Lecturer in the Biologic Sciences", "Board of Directors, ex officio" and "Community Service Award". Margaret Offermann is also a published doctor. She has 46 publication published. The most recent publication is: Induction of human herpesvirus-8 DNA replication and transcription by butyrate and TPA in BCBL-1 cells.
Publications
- Biomarkers and sustainable innovation in cardiovascular drug development: lessons from near and far afield.
- Targeting human herpesvirus-8 for treatment of Kaposi's sarcoma and primary effusion lymphoma.
- The targeting of primary effusion lymphoma cells for apoptosis by inducing lytic replication of human herpesvirus 8 while blocking virus production.
- Protein kinase R mediates intestinal epithelial gene remodeling in response to double-stranded RNA and live rotavirus.
- Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif.
- Inhibition of infection and replication of human herpesvirus 8 in microvascular endothelial cells by alpha interferon and phosphonoformic acid.
- Short duration of elevated vIRF-1 expression during lytic replication of human herpesvirus 8 limits its ability to block antiviral responses induced by alpha interfero...
- IFN-alpha sensitizes human umbilical vein endothelial cells to apoptosis induced by double-stranded RNA.
- Characterization of entry mechanisms of human herpesvirus 8 by using an Rta-dependent reporter cell line.
- Activation of cellular and heterologous promoters by the human herpesvirus 8 replication and transcription activator.
- Human herpesvirus 8 presence and viral load are associated with the progression of AIDS-associated Kaposi''s sarcoma.
- Kaposi''s sarcoma associated herpesvirus G-protein coupled receptor activation of cyclooxygenase-2 in vascular endothelial cells.
- The era of targeted therapies.
- Repeated measures study of human herpesvirus 8 (HHV-8) DNA and antibodies in men seropositive for both HHV-8 and HIV.
- Inhibition of infectious human herpesvirus 8 production by gamma interferon and alpha interferon in BCBL-1 cells.
- Risk factors for Kaposi''s sarcoma in men seropositive for both human herpesvirus 8 and human immunodeficiency virus.
- Induction of human herpesvirus 8 gene expression in a posttransplantation primary effusion lymphoma cell line.
- Induction of human herpesvirus-8 DNA replication and transcription by butyrate and TPA in BCBL-1 cells.
- Transcriptional activation by the human herpesvirus-8-encoded interferon regulatory factor.
- Human herpesvirus 8 encodes an interferon regulatory factor (IRF) homolog that represses IRF-1-mediated transcription.
- Purified Tat induces inflammatory response genes in Kaposi's sarcoma cells.
- Interleukin 1beta induces expression of human herpesvirus 8 encoded genes in BCBL-1 cells.
- Ebola virus inhibits induction of genes by double-stranded RNA in endothelial cells.
- Valproic acid induces human herpesvirus 8 lytic gene expression in BCBL-1 cells.
- Activation of the double-stranded-RNA-activated protein kinase and induction of vascular cell adhesion molecule-1 by poly (I).poly (C) in endothelial cells.
- Lack of responsiveness of a nuclear factor-kappaB-regulated promoter to transactivation by human immunodeficiency virus 1 Tat in HeLa cells.
- Antioxidant-sensitive regulation of inflammatory-response genes in Kaposi's sarcoma cells.
- Induction of IL-6 gene expression in Kaposi's sarcoma cells.
- Regulation of adhesion molecule expression in Kaposi's sarcoma cells.
- Double-stranded RNA induces sickle erythrocyte adherence to endothelium: a potential role for viral infection in vaso-occlusive pain episodes in sickle cell anemia.
- Modulation of double-stranded RNA-mediated gene induction by interferon in human umbilical vein endothelial cells.
- Induction of intercellular adhesion molecule 1 gene expression by measles virus in human umbilical vein endothelial cells.
- Kaposi sarcoma herpesvirus-encoded interferon regulator factors.
- Consideration of host-viral interactions in the pathogenesis of Kaposi's sarcoma.
- HHV-8: a new herpesvirus associated with Kaposi''s sarcoma.
- Multiple signaling cascades are differentially involved in gene induction by double stranded RNA in interferon-alpha-primed cells.
- Interferon-alpha synergistically enhances induction of interleukin-6 by double stranded RNA in HeLa cells.
- Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells.
- Transfection of IFNalpha in human glioblastoma cells and tumorigenicity in association with induction of PKR and OAS gene expression.
- Ebola virus selectively inhibits responses to interferons, but not to interleukin-1beta, in endothelial cells.
- Strain-specific differences in LFA-1 induction on measles virus-infected monocytes and adhesion and viral transmission to endothelial cells.
- Kaposi''s sarcoma and HHV-8.
- Effect of cellular density and viral oncogenes on the major histocompatibility complex class I antigen response to gamma-interferon in BALB-c/3T3 cells.
- Antioxidants and atherosclerosis: a molecular perspective.
- Autocrine induction of major histocompatibility complex class I antigen expression results from induction of beta interferon in oncogene-transformed BALB/c-3T3 cells.
Schools
Virginia Commonwealth University Medical College Of Virginia School Of Medicine
Dana Farber Cancer Institute
University Of Chicago Hosps
Doctors Specialties
- Medical Oncology
- Oncology
Accepted Insurances
Awards
- President
- Executive Committee
- Alpha Omega Alpha Medical Honor Society
- Commencement Speaker, Bryan University Program in Applied Healthcare Informatics
- Board of Directors
- Charlotte Haywood Endowed Lecturer in the Biologic Sciences
- Board of Directors, ex officio
- Community Service Award
Education
-
University of Chicago -
Virginia Commonwealth University School of Medicine
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