Chair, Department of Psychiatry and Psychology
Psychiatry
Dr. Mark A. Frye, MD
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Mark A. Frye practices Psychiatry. He went to University of Minnesota Medical School. University of Minnesota Medical School is ranked 40 in research and 10 in primary care medicine He over the years received 10 awards: "Regional Top Doctor", "Mogens Schou Award for Education", "Rome Mentorship Award", "Outstanding Faculty and Outstanding Course Directors Award", "Best Doctors in America", "Gerald Klerman Young Investigator Award", "Travel Awardee", "WCCBP Fellow", "Ginsberg Fellowship" and "International Health Education Award". Dr. Mark A. Frye is a published MD. He has 102 publications published. The most current publication "Gender-specific effects of comorbid depression and anxiety on the propensity to drink in negative emotional states." Mark A. Frye accepts all Medicare patients.
Publications
- Antidepressant actions of lateral habenula deep brain stimulation differentially correlate with CaMKII/GSK3/AMPK signaling locally and in the infralimbic cortex.
- TSPAN5, ERICH3 and selective serotonin reuptake inhibitors in major depressive Disorder: pharmacometabolomics-informed pharmacogenomics.
- Prevalence and correlates of DSM-5 eating disorders in patients with Bipolar disorder.
- Long-term safety and efficacy of armodafinil in Bipolar depression: A 6-month open-label extension study.
- Sex differences in the risk of rapid cycling and other indicators of adverse illness course in patients with Bipolar I and II disorder.
- Association of brain-derived neurotrophic factor (BDNF) Val66Met polymorphism with early-onset Bipolar disorder.
- The association between sleep disturbances and alcohol relapse: A 12-month observational cohort study.
- Clinical risk factors and serotonin transporter gene variants associated with antidepressant-induced mania.
- Female smokers have the highest alcohol craving in a residential alcoholism treatment cohort.
- Olfactory neuromodulation of motion vision circuitry in Drosophila.
- Balancing benefits and harms of treatments for acute Bipolar depression.
- Current landscape, unmet needs, and future directions for treatment of Bipolar depression.
- Influence of birth cohort on age of onset cluster analysis in Bipolar I disorder.
- N-acetylaspartate normalization in Bipolar depression after lamotrigine treatment.
- Bipolar disorder symptoms in patients seeking bariatric surgery.
- Different patterns of manic/hypomanic symptoms in depression: A pilot modification of the hypomania checklist-32 to assess mixed depression.
- Verbal abuse, like physical and sexual abuse, in childhood is associated with an earlier onset and more difficult course of Bipolar disorder.
- Change in consumption patterns for treatment-seeking patients with alcohol use Disorder post-bariatric surgery.
- Bipolar disorder with comorbid binge eating history: A genome-wide association study implicates APOB.
- Relationship of clinical course of illness variables to medical comorbidities in 900 adult outpatients with Bipolar disorder.
- Risk of myocardial infarction and stroke in Bipolar disorder: a systematic review and exploratory meta-analysis.
- Relationship between sunlight and the age of onset of Bipolar disorder: An international multisite study.
- An electronic health record driven algorithm to identify incident antidepressant medication users.
- More Medical Comorbidities in Patients With Bipolar Disorder From the United States Than From the Netherlands and Germany.
- Association of GATA4 sequence variation with alcohol dependence.
- Figure-ground discrimination behavior in Drosophila. I. Spatial organization of wing-steering responses.
- Figure-ground discrimination behavior in Drosophila. II. Visual influences on head movement behavior.
- The course of sleep disturbances in early alcohol recovery: an observational cohort study.
- Genome-wide association study of Bipolar disorder accounting for effect of body mass index identifies a new risk allele in TCF7L2.
- Centromedian-parafascicular deep brain stimulation induces differential functional inhibition of the motor, associative, and limbic circuits in large animals.
- Increased parental history of Bipolar disorder in the United States: association with early age of onset.
- Group interpersonal and social rhythm therapy for Bipolar depression.
- More stressors prior to and during the course of Bipolar illness in patients from the United States compared with the Netherlands and Germany.
- A retrospective study of gender differences in Depressive symptoms and risk of relapse in patients with alcohol dependence.
- A Feasibility Study of Varenicline for Smoking Cessation in Bipolar Patients With Subsyndromal Depression.
- Higher-order figure discrimination in fly and human vision.
- Lack of differential motor outcome with subthalamic nucleus region stimulation in Parkinson's disease.
- Clinical phenotype of Bipolar disorder with comorbid binge eating disorder.
- Use of a novel adjunctive clinical trial design to examine efficacy, safety of armodafinil for the treatment of Bipolar I depression.
- A double-blind, placebo-controlled, multicenter trial of adjunctive armodafinil for the treatment of major depression associated with Bipolar I disorder.
- Animal behavior: fly flight moves forward.
- Replication of Genome Wide Association Studies of Alcohol Dependence: Support for Association with Variation in ADH1C.
- Hypovitaminosis d in psychogeriatric inpatients.
- Nucleus accumbens deep brain stimulation results in insula and prefrontal activation: a large animal FMRI study.
- Paradigm shift: preliminary clinical categorization of ultrahigh risk for childhood Bipolar disorder to facilitate studies on prevention.
- Drosophila Tracks Carbon Dioxide in Flight.
- Role of childhood adversity in the development of medical co-morbidities associated with Bipolar disorder.
- Visual Attention: A Cell that Focuses on One Object at a Time.
- Bipolar mixed states: an international society for Bipolar disorders task force report of symptom structure, course of illness, and diagnosis.
- Short TE (7) Li-MRS confirms Bi-exponential lithium T2 relaxation in humans and clearly delineates two patient subtypes.
- Alcohol craving as a predictor of relapse.
- Comparing the Beck Depression Inventory-II (BDI-II) and Patient Health Questionnaire (PHQ-9) depression measures in an integrated mood Disorders practice.
- Ethanol withdrawal-induced brain metabolites and the pharmacological effects of acamprosate in mice lacking ENT1.
- An olfactory circuit increases the fidelity of visual behavior.
- International consensus group on depression prevention in Bipolar disorder.
- Review of Pharmacological Treatment in Mood Disorders and Future Directions for Drug Development.
- Direct costs of Bipolar disorder versus other chronic conditions: an employer-based health plan analysis.
- Odor identity influences tracking of temporally patterned plumes in Drosophila.
- Pharmacogenomics of antidepressant induced mania: A review and meta-analysis of the serotonin transporter gene (5HTTLPR) association.
- Voltage-Dependent Mania After Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease: A Case Report.
- Clinical practice. Bipolar disorder--a focus on depression.
- Adjunctive armodafinil for major depressive episodes associated with Bipolar I disorder: a randomized, multicenter, double-blind, placebo-controlled, proof-of-concept ...
- Complexity of pharmacologic treatment required for sustained improvement in outpatients with Bipolar disorder.
- Early-onset Bipolar disorder and treatment delay are risk factors for poor outcome in adulthood.
- Gender and depressive symptoms in 711 patients with Bipolar disorder evaluated prospectively in the Stanley Foundation Bipolar treatment outcome network.
- Multisensory integration for odor tracking by flying Drosophila: Behavior, circuits and speculation.
- Olanzapine/fluoxetine combination for the treatment of mixed depression in Bipolar I disorder: a post hoc analysis.
- Mood stabilization and destabilization during acute and continuation phase treatment for Bipolar I disorder with lamotrigine or placebo.
- Disrupting Disordered neurocircuitry: treating refractory psychiatric illness with neuromodulation.
- Impact of antidepressant continuation after acute positive or partial treatment response for Bipolar depression: a blinded, randomized study.
- Correlates of treatment-emergent mania associated with antidepressant treatment in Bipolar depression.
- The neuro-ecology of resource localization in Drosophila: behavioral components of perception and search.
- Visually mediated odor tracking during flight in Drosophila.
- Diagnostic dilemmas and clinical correlates of mixed states in Bipolar disorder.
- Aripiprazole efficacy in irritability and disruptive-aggressive symptoms: young mania rating scale line analysis from two, randomized, double-blind, placebo-controlled...
- Six-month prospective life charting of mood symptoms with lamotrigine monotherapy versus placebo in rapid cycling Bipolar disorder.
- Increased anterior cingulate/medial prefrontal cortical glutamate and creatine in Bipolar depression.
- Bipolar depression: best practices for the hospitalized patient.
- A placebo-controlled evaluation of adjunctive modafinil in the treatment of Bipolar depression.
- Lack of mania prophylaxis associated with lamotrigine monotherapy in manic-predominant Bipolar I disorder.
- The poor prognosis of childhood-onset Bipolar disorder.
- Visual edge orientation shapes free-flight behavior in Drosophila.
- Increased Suicidality in mania complicated by alcoholism.
- Low cerebrospinal fluid glutamate and glycine in refractory affective Disorder.
- Free-flight odor tracking in Drosophila is consistent with an optimal intermittent scale-free search.
- Defining the clinical course of Bipolar disorder: response, remission, relapse, recurrence, and roughening.
- New findings from the Bipolar Collaborative Network: clinical implications for therapeutics.
- Double-blind, randomized, placebo-controlled trials of ethyl-eicosapentanoate in the treatment of Bipolar depression and rapid cycling Bipolar disorder.
- Incidence and time course of subsyndromal symptoms in patients with Bipolar I disorder: an evaluation of 2 placebo-controlled maintenance trials.
- Subsyndromal depressive symptoms are associated with functional impairment in patients with Bipolar disorder: results of a large, multisite study.
- Healthcare resource utilization in Bipolar depression compared with unipolar depression: results of a United States population-based study.
- Discharge against medical advice from inpatient psychiatric treatment: a literature review.
- Risk of switch in mood polarity to hypomania or mania in patients with Bipolar depression during acute and continuation trials of venlafaxine, sertraline, and bupropio...
- Lower switch rate in depressed patients with Bipolar II than Bipolar I disorder treated adjunctively with second-generation antidepressants.
- Predictors of Bipolar disorder risk among patients currently treated for major depression.
- Use of health care services among persons who screen positive for Bipolar disorder.
- Clinical and legal characteristics of inmates with Bipolar disorder.
- Mixed hypomania in 908 patients with Bipolar disorder evaluated prospectively in the Stanley Foundation Bipolar Treatment Network: a sex-specific phenomenon.
- Comparison of rapid-cycling and non-rapid-cycling Bipolar disorder based on prospective mood ratings in 539 outpatients.
- Relationship between criminal arrest and community treatment history among patients with Bipolar disorder.
- Gender-specific effects of comorbid depression and Anxiety on the propensity to drink in negative emotional states.
Schools
University Of Minnesota Medical School
Clinical Center At The Nih
UCLA Neuropsych Hospital
Procedures Preformed
- Group Psychotherapy
Conditions Treated
- Anxiety
- Bipolar Disorder
- Borderline Personality Disorder
- Dysthymia and Cyclothymia (Mood Disorders)
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Doctors Specialties
- Psychiatry
Accepted Insurances
Awards
- Regional Top Doctor
- Mogens Schou Award for Education
- Rome Mentorship Award
- Outstanding Faculty and Outstanding Course Directors Award
- Best Doctors in America
- Gerald Klerman Young Investigator Award
- Travel Awardee
- WCCBP Fellow
- Ginsberg Fellowship
- International Health Education Award
Education
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National Institutes of Health Clinical Center -
UCLA Neuropsychiatric Hospital -
University of Minnesota Medical School
Hospital
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Mayo Clinic - Rochester, Minnesota
Drug Facts
| NPI NUMBER | 1609892603 | |
| NPPES Provider LastName | FRYE | |
| NPPES Provider FirstName | MARK | |
| NPPES Provider ZIPCode | 559050001 | |
| NPPES Provider State | MN | |
| Specialty Description | Psychiatry | |
| Total Claim Count | 44.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1609892603 |
| Last Name Of The Provider | FRYE |
| First Name Of The Provider | MARK |
| View All |
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