Associate Professor, Pathology, University of Texas Southwestern Medical Center, Southwestern Medical School
Pathology
Dr. Mark H. Siegelman, MD
|
|
Give Review
Mark Siegelman practices Pathology. He went to medical school at University of Texas Southwestern Medical School. Mark Siegelman has written publications. He has 24 publications published with PubMed. The lastest publication is: 'Selective requirements for leukocyte adhesion molecules in models of acute and chronic cutaneous inflammation: participation of E- and P- but not L-selectin.'
Publications
- Suppressor activity and potency among regulatory T cells is discriminated by functionally active CD44.
- The mouse lymph node homing receptor is identical with the lymphocyte cell surface marker Ly-22: role of the EGF domain in endothelial binding.
- Structural studies on the murine Ia alloantigens. IV. NH2-terminal sequence analysis of allelic products of the I-A and I-E/C subregions.
- Normal hematopoiesis and inflammatory responses despite discrete signaling defects in Galpha15 knockout mice.
- Expression of the TAL1 proto-oncogene in cultured endothelial cells and blood vessels of the spleen.
- Rapid, nonradioactive screening for mutations in exons 10, 11, and 16 of the RET protooncogene associated with inherited medullary thyroid carcinoma.
- Eosinophil recruitment to the lung in a murine model of allergic inflammation. The role of T cells, chemokines, and adhesion receptors.
- Circulating activated platelets reconstitute lymphocyte homing and immunity in L-selectin-deficient mice.
- More than the sum of the parts: cooperation between leukocyte adhesion receptors during extravasation.
- Requirement for CD44 in activated T cell extravasation into an inflammatory site.
- Activation and interaction of CD44 and hyaluronan in immunological systems.
- CD44 activation and associated primary adhesion is inducible via T cell receptor stimulation.
- Interleukin 15 induces endothelial hyaluronan expression in vitro and promotes activated T cell extravasation through a CD44-dependent pathway in vivo.
- CD44 and its ligand hyaluronate mediate rolling under physiologic flow: a novel lymphocyte-endothelial cell primary adhesion pathway.
- Hyaluronan anchoring and regulation on the surface of vascular endothelial cells is mediated through the functionally active form of CD44.
- The CD44-initiated pathway of T-cell extravasation uses VLA-4 but not LFA-1 for firm adhesion.
- The route of antigen entry determines the requirement for L-selectin during immune responses.
- Functional activation of lymphocyte CD44 in peripheral blood is a marker of autoimmune disease activity.
- Proinflammatory stimuli regulate endothelial hyaluronan expression and CD44/HA-dependent primary adhesion.
- Selective requirements for leukocyte adhesion molecules in models of acute and chronic cutaneous inflammation: participation of E- and P- but not L-selectin.
- Bimolecular complex between rolling and firm adhesion receptors required for cell arrest; CD44 association with VLA-4 in T cell extravasation.
- L-Selectin-deficient SJL and C57BL/6 mice are not resistant to experimental autoimmune encephalomyelitis.
- Polymorphisms, mutations, and amplification of the EGFR gene in non-small cell lung cancers.
Schools
University of Texas Southwestern Medical Center At Dallas
Stanford University Hospital
Doctors Specialties
- Pathology
Accepted Insurances
Education
-
Stanford University -
University of Texas Southwestern Medical School
Hospital
-
University of Texas Southwestern Medical Center
Helpful Reviews
Similar Doctors
|
|
Dr. Michael E. Black, MD
 This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Aviva M. Hopkovitz, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Imrana Khalid, MD
This Doctor is OpenDoctor Recommended.
|