Associate Professor of Orthopedic Surgery, Boston Children's Hospital
Orthopaedic Surgery
Dr. Martha M. Murray, MD
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Doctor Martha M. Murray, MD is an expert in the field of Orthopaedic Surgery. She went to medical school at Perelman School of Medicine at the University of Pennsylvania. She received awards:"Kappa Delta Award", "Cabaud Award", "Top 100 Most Creative Minds in Business", "NIH/NIAMS Advisory Council Member", "Nominated for Medicine and Healthcare", "The ACL Handbook", "Best Paper Prize", "Distinguished Career Award", "Traveling Scientist", "Basic Science Poster Prize", "Kilfoyle Award", "50th Anniversary Scholar in Medicine-Young Faculty Research Award", "Cabaud Memorial Award", "Charles H. Herndon Award", "AOA Election", "Faculty Award" and "First Place, Senior Design Project Competition". Dr. Martha M. Murray is a published doctor and has 92 publications published. The lastest was: 'Immediate Administration of Intraarticular Triamcinolone Acetonide after Joint Injury Modulates Molecular Outcomes Associated with Early Synovitis.' She accepts Medicare payments and is registered with Medicare.gov.
Publications
- T2 * relaxometry and volume predict semi-quantitative histological scoring of an ACL bridge-enhanced primary repair in a porcine model.
- Biomechanical Outcomes of Bridge-enhanced Anterior Cruciate Ligament Repair Are Influenced by Sex in a Preclinical Model.
- Can platelet-rich plasma enhance Anterior cruciate ligament and meniscal repair?
- Addition of autologous mesenchymal stem cells to whole blood for bioenhanced ACL repair has no benefit in the porcine model.
- Electron beam sterilization does not have a detrimental effect on the ability of extracellular matrix scaffolds to support in vivo Ligament healing.
- Bio-Enhanced Repair of the Anterior Cruciate Ligament.
- Validation of Porcine Knee as a Sex-specific Model to Study Human Anterior Cruciate Ligament Disorders.
- A Normative Study of the Synovial Fluid Proteome from Healthy Porcine Knee Joints.
- Patterns of systemic lupus erythematosus expression in Europe.
- Improving the clinical efficiency of T2(â) mapping of Ligament integrity.
- Increased platelet concentration does not improve functional graft healing in bio-enhanced ACL reconstruction.
- Expression of modulators of extracellular matrix structure after Anterior cruciate ligament injury.
- T2 * MR relaxometry and Ligament volume are associated with the structural properties of the healing ACL.
- Increasing platelet concentration in platelet-rich plasma inhibits Anterior cruciate ligament cell function in three-dimensional culture.
- Biology of Anterior cruciate ligament injury and repair: Kappa delta ann doner vaughn award paper 2013.
- Loss of extracellular matrix from articular cartilage is mediated by the synovium and ligament after Anterior cruciate ligament injury.
- Use of a bioactive scaffold to stimulate Anterior cruciate ligament healing also minimizes posttraumatic osteoarthritis after surgery.
- 2011 AOA Symposium: Tissue Engineering and Tissue Regeneration: AOA Critical Issues.
- In Situ, Noninvasive, T2*-Weighted MRI-Derived Parameters Predict Ex Vivo Structural Properties of an Anterior Cruciate Ligament Reconstruction or Bioenhanced Primary ...
- Effects of Suture Choice on Biomechanics and Physeal Status After Bioenhanced Anterior Cruciate Ligament Repair in Skeletally Immature Patients: A Large-Animal Study.
- Mesenchymal stem cells from the retropatellar fat pad and peripheral blood stimulate ACL fibroblast migration, proliferation, and collagen gene expression.
- Safety of Intra-Articular Use of Atelocollagen for Enhanced Tissue Repair.
- Peripheral blood mononuclear cells enhance the anabolic effects of platelet-rich plasma on Anterior cruciate ligament fibroblasts.
- Biomechanical Outcomes After Bioenhanced Anterior Cruciate Ligament Repair and Anterior Cruciate Ligament Reconstruction Are Equal in a Porcine Model.
- The use of magnetic resonance imaging to predict ACL graft structural properties.
- Decellularization of bovine Anterior cruciate ligament tissues minimizes immunogenic reactions to alpha-gal epitopes by human peripheral blood mononuclear cells.
- The Effect of Synovial Fluid Enzymes on the Biodegradability of Collagen and Fibrin Clots.
- The Effect of Platelet Concentrates on Graft Maturation and Graft-Bone Interface Healing in Anterior Cruciate Ligament Reconstruction in Human Patients: A Systematic R...
- A comparative anatomical study of the human Knee and six animal species.
- Effect of Anterior cruciate healing on the uninjured ligament insertion site.
- Effects of age and platelet-rich plasma on ACL cell viability and collagen gene expression.
- Reduced platelet concentration does not harm PRP effectiveness for ACL repair in a porcine in vivo model.
- Mesenchymal stem cell characteristics of human Anterior cruciate ligament outgrowth cells.
- Treating Anterior cruciate ligament tears in skeletally immature patients.
- Platelet activation by collagen provides sustained release of anabolic cytokines.
- Erythrocytes inhibit Ligament fibroblast proliferation in a collagen scaffold.
- The potential for primary repair of the ACL.
- VEGF receptor mRNA expression by ACL fibroblasts is associated with functional healing of the ACL.
- Delay of 2 or 6 weeks adversely affects the functional outcome of augmented primary repair of the porcine Anterior cruciate ligament.
- Bone-to-bone fixation enhances functional healing of the porcine Anterior cruciate ligament using a collagen-platelet composite.
- The effect of skeletal maturity on functional healing of the Anterior cruciate ligament.
- Human Anterior cruciate ligament fibroblasts from immature patients have a stronger in vitro response to platelet concentrates than those from mature individuals.
- Immature animals have higher cellular density in the healing Anterior cruciate ligament than adolescent or adult animals.
- Age dependence of expression of growth factor receptors in porcine ACL fibroblasts.
- Collagen scaffold supplementation does not improve the functional properties of the repaired Anterior cruciate ligament.
- Platelets and plasma proteins are both required to stimulate collagen gene expression by Anterior cruciate ligament cells in three-dimensional culture.
- The effect of skeletal maturity on the regenerative function of intrinsic ACL cells.
- Collagen density significantly affects the functional properties of an engineered provisional scaffold.
- Translational studies in Anterior cruciate ligament repair.
- TRITON-X is most effective among three decellularization agents for ACL tissue engineering.
- Collagen-platelet composite enhances biomechanical and histologic healing of the porcine Anterior cruciate ligament.
- Posterior periosteal disruption in Salter-Harris Type II fractures of the distal femur: evidence for a hyperextension mechanism.
- Collagen-platelet composites improve the biomechanical properties of healing Anterior cruciate ligament grafts in a porcine model.
- Platelet-rich plasma alone is not sufficient to enhance suture repair of the ACL in skeletally immature animals: an in vivo study.
- The use of platelets to affect functional healing of an Anterior cruciate ligament (ACL) autograft in a caprine ACL reconstruction model.
- Genome-wide expression analysis of intra- and extraarticular connective tissue.
- Current status and potential of primary ACL repair.
- Can suture repair of ACL transection restore normal anteroPosterior laxity of the knee? An ex vivo study.
- Platelets, but not erythrocytes, significantly affect cytokine release and scaffold contraction in a provisional scaffold model.
- Activation of platelet-rich plasma using soluble type I collagen.
- Strategies to improve Anterior cruciate ligament healing and graft placement.
- Enhanced histologic repair in a central wound in the Anterior cruciate ligament with a collagen-platelet-rich plasma scaffold.
- Lateral entry compared with medial and lateral entry pin fixation for completely displaced supracondylar humeral Fractures in children. A randomized clinical trial.
- Collagen-platelet rich plasma hydrogel enhances primary repair of the porcine Anterior cruciate ligament.
- Pathologic characteristics of the torn human meniscus.
- Increased blood lead levels in an adolescent girl from a retained bullet. A case report.
- Use of a collagen-platelet rich plasma scaffold to stimulate healing of a central defect in the canine ACL.
- Interspecies variation in the fibroblast distribution of the Anterior cruciate ligament.
- Enhanced repair of the Anterior cruciate ligament by in situ gene transfer: evaluation in an in vitro model.
- The death of articular chondrocytes after intra-articular Fracture in humans.
- The biomechanical response to doses of TGF-beta 2 in the healing rabbit medial collateral Ligament.
- Cell outgrowth from the human ACL in vitro: regional variation and response to TGF-beta1.
- BMP12 and BMP13 gene transfer induce ligamentogenic differentiation in mesenchymal progenitor and Anterior cruciate ligament cells.
- Fibrin concentration affects ACL fibroblast proliferation and collagen synthesis.
- In situ IGF-1 gene delivery to cells emerging from the injured Anterior cruciate ligament.
- The effect of thrombin on ACL fibroblast interactions with collagen hydrogels.
- The central ACL defect as a model for failure of intra-articular healing.
- Migration of cells from human Anterior cruciate ligament explants into collagen-glycosaminoglycan scaffolds.
- The migration of cells from the ruptured human Anterior cruciate ligament into collagen-glycosaminoglycan regeneration templates in vitro.
- Injection temperature significantly affects in vitro and in vivo performance of collagen-platelet scaffolds.
- Fibroblast distribution in the anteromedial bundle of the human Anterior cruciate ligament: the presence of alpha-smooth muscle actin-positive cells.
- Histological changes in the human Anterior cruciate ligament after rupture.
- Storage conditions do not have detrimental effect on allograft collagen or scaffold performance.
- Outgrowth of chondrocytes from human articular cartilage explants and expression of alpha-smooth muscle actin.
- The presence of smooth muscle actin in fibroblasts in the torn human rotator cuff.
- Distribution of smooth muscle actin-containing cells in the human meniscus.
- Combinations of variations in multiple genes are associated with hypertension.
- The tissue plasminogen activator gene promoter: a novel tool for radiogenic gene therapy of the prostate?
- Basic science of Anterior cruciate ligament injury and repair.
- Gene expression of catabolic inflammatory cytokines peak before anabolic inflammatory cytokines after ACL injury in a preclinical model.
- Immediate Administration of Intraarticular Triamcinolone Acetonide after Joint Injury Modulates Molecular Outcomes Associated with Early Synovitis.
Schools
University Of Pennsylvania School Of Medicine
Massachusetts General Hospital
Harvard Combined Residency
Brigham and Women39s Hospital
Children39s Hospital Boston
Conditions Treated
- Anterior Cruciate Ligament (ACL) or Posterior Cruciate Ligament (PCL) Tear
- Bursitis
- Chronic Pelvic Pain
- Enthesopathy of Knee (incl. Bursitis of Knee)
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Doctors Specialties
- Sports Medicine
- Orthopaedic Surgery
Accepted Insurances
Awards
- Kappa Delta Award
- Cabaud Award
- Top 100 Most Creative Minds in Business
- NIH/NIAMS Advisory Council Member
- Nominated for Medicine and Healthcare
- The ACL Handbook
- Best Paper Prize
- Distinguished Career Award
- Traveling Scientist
- Basic Science Poster Prize
- Kilfoyle Award
- 50th Anniversary Scholar in Medicine-Young Faculty Research Award
- Cabaud Memorial Award
- Charles H. Herndon Award
- AOA Election
- Faculty Award
- First Place, Senior Design Project Competition
Education
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Massachusetts General Hospital -
Perelman School of Medicine at the University of Pennsylvania
Hospital
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Boston Children's Hospital
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