Physician
Orthopaedic Surgery
Dr. Michael S. Shuler, MD
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Michael Shuler works in the field of Orthopaedic Surgery. He researched medicine at Johns Hopkins University School of Medicine. Johns Hopkins University School of Medicine is a one of the best medicals schools. Johns Hopkins University School of Medicine is ranked 3 in research and 29 in primary care medicine Michael Shuler is a published doctor and has 101 publications published. The lastest was: 'Subcutaneous depth in a traumatized lower extremity.' Michael Shuler is registered with Medicare and accepts Medicare payments.
Publications
- Subcutaneous depth in a traumatized lower extremity.
- Correlation of near-infrared spectroscopy and direct pressure monitoring in an acute porcine compartmental Syndrome model.
- How multi-organ microdevices can help foster drug development.
- Identification of optimal control compartments for serial near-infrared spectroscopy assessment of lower extremity compartmental perfusion.
- Relationship between Near Infrared Spectroscopy and Intra-compartmental Pressures.
- Independent component analyses for quantifying neuronal ensemble interactions.
- Solving medical problems with BioMEMS.
- Integration of in silico and in vitro platforms for pharmacokinetic-pharmacodynamic modeling.
- Metacridamides A and B, Macrocycles from Conidia of the Entomopathogenic Fungus Metarhizium acridum.
- Batch, fed-batch, and microcarrier cultures with CHO cell lines in a pressure-cycle driven miniaturized bioreactor.
- Characterization of in vitro endothelial linings grown within microfluidic channels.
- Paclitaxel delivery to brain tumors from hydrogels: a computational study.
- Microscale 3-D hydrogel scaffold for biomimetic gastrointestinal (GI) tract model.
- Murine in vitro model of the blood-brain barrier for evaluating drug transport.
- An uncertain role for Cu(II) in stimulating Mn(II) oxidation by Leptothrix Discophora SS-1.
- Surface-enhanced localized surface plasmon resonance biosensing of avian influenza DNA hybridization using subwavelength metallic nanoarrays.
- Engineered bacterial outer membrane vesicles with enhanced functionality.
- Optical measurement of neural activity using surface plasmon resonance.
- Accelerating innovation between surgeons and biomedical engineers in the academic setting.
- Macromolecular crowding can account for RNase-sensitive constraint of bacterial nucleoid structure.
- Effects of glial cells on electrode impedance recorded from neuralprosthetic devices in vitro.
- Promises, challenges and future directions of microCCAs.
- A microfluidic device for a pharmacokinetic-pharmacodynamic (PK-PD) model on a chip.
- Complex responses to culture conditions in Pseudomonas syringae pv. tomato DC3000 continuous cultures: the role of iron in cell growth and virulence factor induction.
- In vitro microscale systems for systematic drug toxicity study.
- Fluorescence optical detection in situ for real-time monitoring of cytochrome P450 enzymatic activity of liver cells in multiple microfluidic devices.
- Design optimization of nano-grating surface plasmon resonance sensors.
- Characterization of a gastrointestinal tract microscale cell culture analog used to predict drug toxicity.
- A micro cell culture analog (microCCA) with 3-D hydrogel culture of multiple cell lines to assess metabolism-dependent cytotoxicity of anti-cancer drugs.
- Quantification of chemical-polymer surface interactions in microfluidic cell culture devices.
- Effect of iron concentration on the growth rate of Pseudomonas syringae and the expression of virulence factors in hrp-inducing minimal medium.
- Prevention of air bubble formation in a microfluidic perfusion cell culture system using a microscale bubble trap.
- A novel system for evaluation of drug mixtures for potential efficacy in treating multidrug resistant cancers.
- Iron requirement for Mn(II) oxidation by Leptothrix Discophora SS-1.
- Development of a stable dual cell-line GFP expression system to study estrogenic endocrine disruptors.
- Cell cycle progression in Escherichia coli B/r affects transcription of certain genes: Implications for synthetic genome design.
- A combined pharmacokinetic-pharmacodynamic (PK-PD) model for tumor growth in the rat with UFT administration.
- Characterization of Caco-2 and HT29-MTX cocultures in an in vitro digestion/cell culture model used to predict iron bioavailability.
- Fabrication of a multiple-diameter branched network of microvascular channels with semi-circular cross-sections using xenon difluoride etching.
- Real-time fluorescence detection of multiple microscale cell culture analog devices in situ.
- A hydrogel-based microfluidic device for the studies of directed cell migration.
- Sensitivity and control analysis of periodically forced reaction networks using the Green''s function method.
- Molecular engineering of epoxide hydrolase and its application to asymmetric and enantioconvergent hydrolysis.
- Spatial distributions of copper in microbial biofilms by scanning electrochemical microscopy.
- Influence of culture medium supplementation of tobacco NT1 cell suspension cultures on the N-glycosylation of human secreted alkaline phosphatase.
- Cloning, expression and enantioselective hydrolytic catalysis of a microsomal epoxide hydrolase from a marine fish, Mugil cephalus.
- A genomically/chemically complete module for synthesis of lipid membrane in a minimal cell.
- Production, secretion, and stability of human secreted alkaline phosphatase in tobacco NT1 cell suspension cultures.
- Evaluation of Mut+ and MutS Pichia pastoris phenotypes for high level extracellular scFv expression under feedBack control of the methanol concentration.
- Effect of the plant peptide regulator, phytosulfokine-alpha, on the growth and Taxol production from Taxus sp. suspension cultures.
- A three-channel microfluidic device for generating static linear gradients and its application to the quantitative analysis of bacterial chemotaxis.
- Antibody-based surface plasmon resonance detection of intact viral pathogen.
- Behavior of lead in a model microbial predator-prey system.
- Development of a gastrointestinal tract microscale cell culture analog to predict drug transport.
- Effect of culture conditions on the degree of sialylation of a recombinant glycoprotein expressed in insect cells.
- Integration of cell culture and microfabrication technology.
- Production of a sialylated N-linked glycoprotein in insect cells: role of glycosidases and effect of harvest time on glycosylation.
- Novel insect cell line capable of complex N-glycosylation and sialylation of recombinant proteins.
- Alterations in Taxol production in plant cell culture via manipulation of the phenylalanine ammonia lyase pathway.
- Hepatitis B surface antigen (HBsAg) expression in plant cell culture: Kinetics of antigen accumulation in batch culture and its intracellular form.
- The effect of ajmalicine spiking and resin addition timing on the production of indole alkaloids from Catharanthus roseus cell cultures.
- Factors important in the extraction, stability and in vitro assembly of the hepatitis B surface antigen derived from recombinant plant systems.
- The effect of various substrates on cell attachment and differentiation of 3T3-F442A preadipocytes.
- Prediction of naphthalene bioaccumulation using an adipocyte cell line model.
- Effect of oxide formation mechanisms on lead adsorption by biogenic manganese (hydr)oxides, iron (hydr)oxides, and their mixtures.
- Incorporation of 3T3-L1 cells to mimic bioaccumulation in a microscale cell culture analog device for toxicity studies.
- Development of a model microbial predator-prey system suitable for studies of the behavior of toxic trace metals.
- Mobilization of adsorbed copper and lead from naturally aged soil by bacterial extracellular polymers.
- The design and fabrication of three-chamber microscale cell culture analog devices with integrated dissolved oxygen sensors.
- Development of a microscale cell culture analog to probe naphthalene toxicity.
- A self-priming microfluidic diaphragm pump capable of recirculation fabricated by combining soft lithography and traditional machining.
- Structural characterization of plant-derived hepatitis B surface antigen employed in oral immunization studies.
- Effect of silkworm hemolymph on N-linked glycosylation in two Trichoplusia ni insect cell lines.
- Portable in situ fluorescence cytometry of microscale cell-based assays.
- Determination of spatial distributions of zinc and active biomass in microbial biofilms by two-photon laser scanning microscopy.
- Relationship of viability and apoptosis to taxol production in Taxus sp. suspension cultures elicited with methyl jasmonate.
- An endothelial and astrocyte co-culture model of the blood-brain barrier utilizing an ultra-thin, nanofabricated silicon nitride membrane.
- Effect of subculture and elicitation on instability of taxol production in Taxus sp. suspension cultures.
- Robust control of initiation of prokaryotic chromosome replication: essential considerations for a minimal cell.
- Glycosylation profiles of the human colorectal cancer A33 antigen naturally expressed in the human colorectal cancer cell line SW1222 and expressed as recombinant prot...
- Predicting the rate and extent of cadmium and copper desorption from soils in the presence of bacterial extracellular polymer.
- Lipid-gel and poly(dimethylsiloxane) film to mimic bioaccumulation in adipocytes.
- A modular minimal cell model: purine and pyrimidine transport and metabolism.
- A simple method for enhancing paclitaxel release from Taxus canadensis cell suspension cultures utilizing cell wall digesting enzymes.
- Towards the development of a minimal cell model by generalization of a model of Escherichia coli: use of dimensionless rate parameters.
- Production of a sialylated N-linked glycoprotein in insect cells.
- The effects of pH and surface composition on Pb adsorption to natural freshwater biofilms.
- Comparison of growth and recombinant protein expression in two different insect cell lines in attached and suspension culture.
- Phenanthrene desorption from soil in the presence of bacterial extracellular polymer: observations and model predictions of dynamic behavior.
- Cell science and protein crystal growth research for the International Space Station.
- Influence of baculovirus-host cell interactions on complex N-linked glycosylation of a recombinant human protein.
- Characterization of a perfusion reactor utilizing mammalian cells on microcarrier beads.
- Process options in hepatitis B surface antigen extraction from transgenic potato.
- Combining cell culture analogue reactor designs and PBPK models to probe mechanisms of naphthalene toxicity.
- Computer model for glucose-limited growth of a single cell of Escherichia coli B/r-A. Reprinted from Biotechnology and Bioengineering, Vol. 26, Issue 3, Pp 203-216 (19...
- The effect of inoculum density and conditioned medium on the production of ajmalicine and catharanthine from immobilized Catharanthus roseus cells.
- Isolation of labeled 9-dihydrobaccatin III and related taxoids from cell cultures of taxuscell cultures of taxus canadensis elicited with m.
- Single-cell models: promise and limitations.
- Independent prediction of naphthalene transport and biodegradation in soil with a mathematical model.
- Use of in vitro data for construction of a physiologically based pharmacokinetic model for naphthalene in rats and mice to probe species differences.
Schools
Johns Hopkins Univ Sch Of Med
Emory University School Of Medicine
University Of Washington Seattle
University of North Carolina At Chapel Hill
Procedures Preformed
- Carpal Tunnel Release
- Carpal Tunnel Release Surgery, Endoscopic
- Carpal Tunnel Release Surgery, Open
- Dressing and-or Debridement of Wound, Infection, or Burn (incl. Negative Pressure Wound Therapy)
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Conditions Treated
- Ankle Fracture
- Ankle Sprain and Achilles Tendon Sprain or Rupture
- Back Pain
- Bursitis
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Doctors Specialties
- Orthopedic Hand Surgery
- Orthopaedic Surgery
Accepted Insurances
Education
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University of Washington -
Emory University -
Johns Hopkins University School of Medicine
Drug Facts
| NPI NUMBER | 1497944565 | |
| NPPES Provider LastName | SHULER | |
| NPPES Provider FirstName | MICHAEL | |
| NPPES Provider ZIPCode | 30606 | |
| NPPES Provider State | GA | |
| Specialty Description | Orthopedic Surgery | |
| Total Claim Count | 456.0 | |
| Distinct Opioid Count | 3.0 | |
| Opioid Claim Count | 233.0 | |
| Percent Opioid Claims | 51.1 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1497944565 |
| Last Name Of The Provider | SHULER |
| First Name Of The Provider | MICHAEL |
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