Professor of Neurology, Johns Hopkins University School of Medicine; Co-director, Michael S. and Karen G. Ansari ALS Center for Cell Therapy and Regeneration Research
Neurology
Dr. Nicholas Maragakis, MD
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Nicholas Maragakis is an expert in the field of Neurology. He went to medical school at University of Utah School of Medicine. He received awards:"CMS Meaningful Use Stage 1 Certification". Nicholas Maragakis is a published doctor as well. He has 55 publications published. The latest was: Primary Lateral Sclerosis and Early Upper Motor Neuron Disease: Characteristics of a Cross-Sectional Population. Nicholas Maragakis accepts Medicare payments and is registered with Medicare.gov.
Publications
- Primary Lateral Sclerosis and Early Upper Motor Neuron Disease: Characteristics of a Cross-Sectional Population.
- Peripheral neuropathy in a family with Sandhoff Disease and SH3TC2 deficiency.
- Human glial progenitor engraftment and gene expression is independent of the ALS environment.
- Transplantation of glial progenitors that overexpress glutamate transporter GLT1 preserves diaphragm function following cervical SCI.
- C9orf72 nucleotide repeat structures initiate molecular cascades of Disease.
- Gene Profiling of Human Induced Pluripotent Stem Cell-Derived Astrocyte Progenitors Following Spinal Cord Engraftment.
- Altered astrocytic expression of TDP-43 does not influence motor neuron survival.
- Electrical impedance myography correlates with standard measures of ALS severity.
- RNA Toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention.
- Peer recommendations on how to improve clinical research, and Conference wrap-up.
- Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral Sclerosis (ALS).
- Amyotrophic lateral Sclerosis: pathogenesis, differential diagnoses, and potential interventions.
- Topiramate protects against motor neuron degeneration in organotypic spinal cord cultures but not in G93A SOD1 transgenic mice.
- Human embryonic germ cell derivatives facilitate motor recovery of rats with diffuse motor neuron injury.
- A novel secretory factor, Neurogenesin-1, provides neurogenic environmental cues for neural stem cells in the adult hippocampus.
- Glutamate transporter expression and function in human glial progenitors.
- Altered expression of the glutamate transporter EAAT2b in neurological Disease.
- Glutamate transporters: animal models to neurologic Disease.
- Viral-induced spinal motor neuron death is non-cell-autonomous and involves glutamate excitoToxicity.
- Neural stem cells protect against glutamate-induced excitoToxicity and promote survival of injured motor neurons through the secretion of neurotrophic factors.
- Glial restricted precursors protect against Chronic glutamate neurotoxicity of motor neurons in vitro.
- Degeneration of respiratory motor neurons in the SOD1 G93A transgenic rat model of ALS.
- Selective up-regulation of the glial Na+-dependent glutamate transporter GLT1 by a neuroimmunophilin ligand results in neuroprotection.
- Loss of the astrocyte glutamate transporter GLT1 modifies Disease in SOD1(G93A) mice.
- Mechanisms of Disease: astrocytes in neurodegenerative Disease.
- Impaired SDF1/CXCR4 signaling in glial progenitors derived from SOD1(G93A) mice.
- Intraparenchymal spinal cord delivery of adeno-associated virus IGF-1 is protective in the SOD1G93A model of ALS.
- Adult glial precursor proliferation in mutant SOD1G93A mice.
- Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron Disease.
- Accurate ALSFRS-R scores can be generated from retrospective review of clinic notes.
- Rethinking a drug treatment failure on a traditional ALS target.
- A targeted neuroglial reporter line generated by homologous recombination in human embryonic stem cells.
- Advances in stem cell research for Amyotrophic Lateral Sclerosis.
- Motor neuron Disease: progressive muscular atrophy in the ALS spectrum.
- Peripheral hyperstimulation alters site of Disease onset and course in SOD1 rats.
- Stem cells and the ALS neurologist.
- Selective ablation of proliferating astrocytes does not affect Disease outcome in either acute or chronic models of motor neuron degeneration.
- A comprehensive library of familial human amyotrophic lateral Sclerosis induced pluripotent stem cells.
- Spatial and temporal changes in promoter activity of the astrocyte glutamate transporter GLT1 following traumatic spinal cord injury.
- Stem cell transplantation for spinal cord neurodegeneration.
- Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo.
- Human glial-restricted progenitor transplantation into cervical spinal cord of the SOD1 mouse model of ALS.
- Lithium may slow progression of amyotrophic lateral Sclerosis, but further study is needed.
- New treatments in amyotrophic lateral Sclerosis.
- Effect of genetic Background on phenotype variability in transgenic mouse models of amyotrophic lateral sclerosis: a window of opportunity in the search for genetic mo...
- Motor neuron Disease occurring in a mutant dynactin mouse model is characterized by defects in vesicular trafficking.
- Protective role of reactive astrocytes in Brain ischemia.
- Correction of humoral derangements from mutant superoxide dismutase 1 spinal cord.
- Recovery from paralysis in adult rats using embryonic stem cells.
- Genetic localization of an autosomal dominant leukodystrophy mimicking Chronic progressive multiple sclerosis to chromosome 5q31.
- Glutamate transporters in neurologic Disease.
- Targeted stem cell transplantation strategies in ALS.
- Multipoint incremental motor unit number estimation as an outcome measure in ALS.
- Pregnenolone sulfate augments NMDA receptor mediated increases in intracellular Ca2+ in cultured rat hippocampal neurons.
Schools
University of Utah
Johns Hopkins University School Med
University Of Ut Med Center
Procedures Preformed
- EEG (Electroencephalogram)
- EMG (Electromyography)
Conditions Treated
- Alzheimer's Background: yellow;'>Background: yellow;'>Background: yellow;'>Background: yellow;'>Background: yellow;'>Background: yellow;'>Background: yellow;'>Background: yellow;'>Background: yellow;'>Background: yellow;'>Background: yellow;'>Disease
- Anterior Horn Background: yellow;'>Background: yellow;'>Background: yellow;'>Background: yellow;'>Background: yellow;'>Background: yellow;'>Background: yellow;'>Background: yellow;'>Background: yellow;'>Background: yellow;'>Background: yellow;'>Disease
- Bell's Palsy
- Brain and Nervous System Cancer (incl. Gliomas, Astrocytoma, Schwannoma, Medulloblastoma, Chordoma)
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Doctors Specialties
- Neurology
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
Education
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Johns Hopkins University -
University of Utah -
University of Utah School of Medicine
Hospital
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Johns Hopkins Hospital
Drug Facts
| NPI NUMBER | 1780626382 | |
| NPPES Provider LastName | MARAGAKIS | |
| NPPES Provider FirstName | NICHOLAS | |
| NPPES Provider ZIPCode | 212870005 | |
| NPPES Provider State | MD | |
| Specialty Description | Neurology | |
| Total Claim Count | 107.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1780626382 |
| Last Name Of The Provider | MARAGAKIS |
| First Name Of The Provider | NICHOLAS |
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