Diet/Nutritionist
Dr. Nicolaas E. Deutz, MD
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Nicolaas Deutz works in the field of Diet/Nutritionist. Nicolaas E. Deutz, MD is a published MD. He published 100 publications, including: 'Quantity of dietary protein intake, but not pattern of intake, affects net protein balance primarily through differences in protein synthesis in older adults.'
Publications
- Quantity of dietary protein intake, but not pattern of intake, affects net protein balance primarily through differences in protein synthesis in older adults.
- Arginine infusion in patients with septic shock increases nitric oxide production without haemodynamic instability.
- Protein is an important but undervalued macronutrient in the nutritional care of patients with cystic fibrosis.
- Increased whole body hydroxyproline production as assessed by a new stable isotope technique is associated with hip and spine bone mineral loss in cystic fibrosis.
- New stable isotope method to measure protein digestibility and response to pancreatic enzyme intake in cystic fibrosis.
- Hydrolyzed casein and whey protein meals comparably stimulate net whole-body protein synthesis in COPD patients with nutritional depletion without an additional effect...
- Effect of ?-hydroxy-?-methylbutyrate (HMB) on lean body mass during 10 days of bed rest in older adults.
- Stimulated Nitric Oxide Production and Arginine Deficiency in Children with Cystic Fibrosis with Nutritional Failure.
- Dietary essential amino acids are highly anabolic in pediatric patients with cystic fibrosis.
- Is there a maximal anabolic response to protein intake with a meal?
- Casein protein results in higher prandial and exercise induced whole body protein anabolism than whey protein in Chronic Obstructive Pulmonary Disease.
- Enhanced anabolic response to milk protein sip feeding in elderly subjects with COPD is associated with a reduced splanchnic extraction of multiple amino acids.
- Use of body mass index percentile to identify fat-free mass depletion in children with cystic fibrosis.
- Muscle protein synthesis in cancer patients can be stimulated with a specially formulated medical food.
- Features, causes and consequences of splanchnic sequestration of amino acid in old rats.
- Increased protein-energy intake promotes anabolism in critically ill infants with viral bronchiolitis: a double-blind randomised controlled trial.
- Is glutamine still an important precursor of citrulline?
- Dose-dependent effects of leucine supplementation on preservation of muscle mass in cancer cachectic mice.
- Effects of L-arginine pretreatment on nitric oxide metabolism and hepatosplanchnic perfusion during porcine endotoxemia.
- Arginine and sepsis: a question of the right balance?
- Arginine improves microcirculation in the free transverse rectus abdominis myocutaneous flap after breast reconstruction: a randomized, double-blind clinical trial.
- Differential metabolic effects of casein and soy protein meals on skeletal muscle in healthy volunteers.
- Acute endotoxemia following transjugular intrahepatic stent-shunt insertion is associated with systemic and cerebral vasodilatation with increased whole body nitric ox...
- Glutamine: precursor or nitrogen donor for citrulline synthesis?
- Nutritional recommendations for the management of sarcopenia.
- Reduced caloric intake during endotoxemia reduces arginine availability and metabolism.
- Glutamine synthetase in muscle is required for glutamine production during fasting and extrahepatic ammonia detoxification.
- Profiling human gut bacterial metabolism and its kinetics using U-13Cglucose and NMR.
- Regulation of nitric oxide production in health and disease.
- Enteral administration of alanyl-2-(15)Nglutamine contributes more to the de novo synthesis of arginine than does intravenous infusion of the dipeptide in humans.
- Acute effects of breakfasts containing alpha-lactalbumin, or gelatin with or without added tryptophan, on hunger, ''satiety'' hormones and amino acid profiles.
- Oral arginine supplementation and the effect on skin graft donor sites: a randomized clinical pilot study.
- Effects of complete whey-protein breakfasts versus whey without GMP-breakfasts on energy intake and satiety.
- A breakfast with alpha-lactalbumin, gelatin, or gelatin + TRP lowers energy intake at lunch compared with a breakfast with casein, soy, whey, or whey-GMP.
- Dose-dependent satiating effect of whey relative to casein or soy.
- Effects of high and normal soyprotein breakfasts on satiety and subsequent energy intake, including amino acid and ''satiety'' hormone responses.
- Comparison of the effects of a high- and normal-casein breakfast on satiety, ''satiety'' hormones, plasma amino acids and subsequent energy intake.
- Application of liquid chromatography-tandem mass spectrometry (LC-MS/MS) for the analysis of stable isotope enrichments of phenylalanine and tyrosine.
- Reduced citrulline production in sepsis is related to diminished de novo arginine and nitric oxide production.
- Reduced citrulline availability by OTC deficiency in mice is related to reduced nitric oxide production.
- Pharmacokinetics of proline-rich tripeptides in the pig.
- Protein synthesis is severely diminished following a simulated upper GI bleed in patients with cirrhosis.
- Enteral feeding induces diet-dependent mucosal dysfunction, bacterial proliferation, and necrotizing enterocolitis in preterm pigs on parenteral nutrition.
- The gut does not contribute to systemic ammonia release in humans without portosystemic shunting.
- Decreased plasma glutamate in early phases of septic shock with acute liver dysfunction is an independent predictor of survival.
- Interorgan synthesis of arginine is down-regulated in tumor-bearing mice undergoing surgical trauma.
- Metabolic and functional effects of glutamate intake in patients with chronic obstructive pulmonary disease (COPD).
- The 2007 ESPEN Sir David Cuthbertson Lecture: amino acids between and within organs. The glutamate-glutamine-citrulline-arginine pathway.
- Glutamine is an important precursor for de novo synthesis of arginine in humans.
- Elevated plasma arginase-1 does not affect plasma arginine in patients undergoing liver resection.
- Effect of major liver resection on hepatic ureagenesis in humans.
- Plasma arginine and citrulline concentrations in critically ill children: strong relation with inflammation.
- New legal regulations for clinical trials: an opportunity for the future of Clinical Nutrition research.
- Measurement of amino acid isotope enrichment by liquid chromatography mass spectroscopy after derivatization with 9-fluorenylmethylchloroformate.
- Exogenous arginine in sepsis.
- The route of administration (enteral or parenteral) affects the conversion of isotopically labeled L-2-15Nglutamine into citrulline and arginine in humans.
- Protein breakdown on whole-body and organ level in non-cachectic tumour-bearing mice undergoing surgery.
- Application of liquid chromatography-mass spectrometry to measure the concentrations and study the synthesis of short chain fatty acids following stable isotope infusi...
- Biomarkers of arginine and lysine excess.
- Intestinal and hepatic metabolism of glutamine and citrulline in humans.
- Methods using stable isotopes to measure nitric oxide (NO) synthesis in the L-arginine/NO pathway in health and disease.
- Presence of tumour inhibits the normal post-operative response in arginine and NO production in non-cachectic mice.
- Identification of glucose-fermenting bacteria present in an in vitro model of the human intestine by RNA-stable isotope probing.
- Isoleucine infusion during "simulated" upper gastrointestinal bleeding improves liver and muscle protein synthesis in cirrhotic patients.
- Supplementation of soy protein with branched-chain amino acids alters protein metabolism in healthy elderly and even more in patients with chronic obstructive pulmonar...
- Interorgan amino acid exchange in humans: consequences for arginine and citrulline metabolism.
- Effects of acute tryptophan depletion on mood and facial emotion perception related brain activation and performance in healthy women with and without a family history...
- Systemic and regional hemodynamics in pigs with acute liver failure and the effect of albumin dialysis.
- Route of administration (enteral or parenteral) affects the contribution of L-glutamine to de novo L-arginine synthesis in mice: a stable-isotope study.
- Interorgan ammonia, glutamate, and glutamine trafficking in pigs with acute liver failure.
- Kidney plays a major role in ammonia homeostasis after portasystemic shunting in patients with cirrhosis.
- Infected chronic wounds show different local and systemic arginine conversion compared with acute wounds.
- The effect of acute tryptophan depletion on the BOLD response during performance monitoring and response inhibition in healthy male volunteers.
- Acute tryptophan depletion improves performance and modulates the BOLD response during a Stroop task in healthy females.
- Acute tryptophan depletion reduces activation in the right hippocampus during encoding in an episodic memory task.
- Increased glutamate levels in the vitreous of patients with retinal detachment.
- Increased nitric oxide (NO) pathway metabolites in the vitreous fluid of patients with rhegmatogenous retinal detachment or diabetic traction retinal detachment.
- Effect of glutamate ingestion on whole-body glutamate turnover in healthy elderly and patients with chronic obstructive pulmonary disease.
- Greater whole-body myofibrillar protein breakdown in cachectic patients with chronic obstructive pulmonary disease.
- ESPEN Guidelines on Enteral Nutrition: Intensive care.
- Effect of albumin dialysis on intracranial pressure increase in pigs with acute liver failure: a randomized study.
- Metabolic effects of glutamine and glutamate ingestion in healthy subjects and in persons with chronic obstructive pulmonary disease.
- Keratinocyte growth factor ameliorates acute graft-versus-host disease in a novel nonmyeloablative haploidentical transplantation model.
- Intestinal renal metabolism of L-citrulline and L-arginine following enteral or parenteral infusion of L-alanyl-L-2,15Nglutamine or L-2,15Nglutamine in mice.
- Decreased whole-body and splanchnic glutamate metabolism in healthy elderly men and patients with chronic obstructive pulmonary disease in the postabsorptive state and...
- Altered interorgan response to feeding in patients with chronic obstructive pulmonary disease.
- Memory function in women with premenstrual complaints and the effect of serotonergic stimulation by acute administration of an alpha-lactalbumin protein.
- NOS3 is involved in the increased protein and arginine metabolic response in muscle during early endotoxemia in mice.
- Casein and soy protein meals differentially affect whole-body and splanchnic protein metabolism in healthy humans.
- Evening intake of alpha-lactalbumin increases plasma tryptophan availability and improves morning alertness and brain measures of attention.
- Plasma arginine concentrations are reduced in cancer patients: evidence for arginine deficiency?
- The role of NOS2 and NOS3 in renal protein and arginine metabolism during early endotoxemia in mice.
- The role of arginine in infection and sepsis.
- Effects of a novel method of acute tryptophan depletion on plasma tryptophan and cognitive performance in healthy volunteers.
- Monitoring myeloablative therapy-induced small bowel toxicity by serum citrulline concentration: a comparison with sugar permeability tests.
- Skeletal muscle glutamate metabolism in health and disease: state of the art.
- Pros and cons of L-arginine supplementation in disease.
- Effects of long-term intravenous and intragastric L-arginine intervention on jejunal motility and visceral nitric oxide production in the hyperdynamic compensated endo...
- Time course of nitric oxide production after endotoxin challenge in mice.
Doctors Specialties
- Dietetics
- Nutrition
- Diet/Nutritionist
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