Professor, Medicine, Jefferson Medical College-Thos Jefferson Univ
Hematology
Dr. Paul F. Bray, MD
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Paul F. Bray, MD is an expert in the field of Hematology. He attended Baylor College of Medicine. He over the years received 2 awards: "CMS Meaningful Use Stage 1 Certification" and "Super Doctor". Paul Bray is a published doctor. He published 99 publications, including: 'Integrin-dependent control of translation: engagement of integrin alphaIIbbeta3 regulates synthesis of proteins in activated human platelets.' He accepts Medicare payments and is listed with Medicare.gov.
Publications
- Common variants in the human Platelet PAR4 thrombin receptor alter Platelet function and differ by race.
- PDK1 selectively phosphorylates Thr(308) on Akt and contributes to human Platelet functional responses.
- Human Platelet microRNA-mRNA networks associated with age and gender revealed by integrated Plateletomics.
- Targeted temperature management after intracerebral hemorrhage (TTM-ICH): methodology of a prospective randomized clinical trial.
- Racial differences in human Platelet PAR4 reactivity reflect expression of PCTP and miR-376c.
- MicroRNAs in Platelet production and activation.
- Small RNAs as Potential Platelet Therapeutics.
- Identification of a specific intronic PEAR1 gene variant associated with greater Platelet aggregability and protein expression.
- Transfection of human Platelets with short interfering RNA.
- Platelet microRNA-mRNA coexpression profiles correlate with Platelet reactivity.
- The 9p21.3 locus: Platelets enter the fray.
- Advancing the research mission in an academic department: the creation of a center for translational medicine.
- Platelet RNA chips dip into thrombocytosis.
- Platelet genomics beats the catch-22.
- R93W mutation in Orai1 causes impaired calcium influx in Platelets.
- Transdermal 17-beta estradiol replacement therapy reduces megakaryocyte GPVI expression.
- Platelet hyperreactivity: predictive and intrinsic properties.
- Heritability of Platelet responsiveness to aspirin in activation pathways directly and indirectly related to cyclooxygenase-1.
- Effect of genetic variations in Platelet glycoproteins Ibalpha and VI on the risk for coronary heart disease events in postmenopausal women taking hormone therapy.
- Genetic polymorphisms of the Platelet receptors P2Y(12), P2Y(1) and GP IIIa and response to aspirin and clopidogrel.
- Relation between atherosclerosis risk factors and aspirin resistance in a primary prevention population.
- Molecular mechanisms of prothrombotic risk due to genetic variations in Platelet genes: Enhanced outside-in signaling through the Pro33 variant of integrin beta3.
- Venous Thrombosis and conjugated equine estrogen in women without a uterus.
- Sex differences in Platelet reactivity and response to low-dose aspirin therapy.
- Effect of Platelet antigen polymorphism on Platelet inhibition by aspirin, clopidogrel, or their combination.
- Aspirin and clopidogrel drug response in patients undergoing percutaneous coronary intervention: the role of dual drug resistance.
- Platelet reactivity and genetics down on the pharm.
- Aggregometry detects Platelet hyperreactivity in healthy individuals.
- Effects of estrogen replacement therapies on mouse Platelet function and glycoprotein VI levels.
- The Pro33 isoform of integrin beta3 enhances outside-in signaling in human Platelets by regulating the activation of serine/threonine phosphatases.
- Platelet gene polymorphisms and cardiac risk assessment in vascular surgical patients.
- Clinical and functional consequences of Platelet membrane glycoprotein polymorphisms.
- Protein phosphatase 1 associates with the integrin alphaIIb subunit and regulates signaling.
- Genetic variation responsible for mouse strain differences in integrin alpha 2 expression is associated with altered Platelet responses to collagen.
- Platelets of female mice are intrinsically more sensitive to agonists than are Platelets of males.
- Elevated factor VIII and portal Vein thrombosis.
- Enhanced activation of mitogen-activated protein kinase and myosin light chain kinase by the Pro33 polymorphism of integrin beta 3.
- Platelet hyperreactivity in women from families with premature atherosclerosis.
- PlA polymorphism of integrin beta 3 differentially modulates cellular migration on extracellular matrix proteins.
- Reduced inhibition by abciximab in Platelets with the PlA2 polymorphism.
- MicroRNA Expression Differences in Human Hematopoietic Cell Lineages Enable Regulated Transgene Expression.
- The human Platelet: strong transcriptome correlations among individuals associate weakly with the Platelet proteome.
- Improved outcomes in diabetes care for rural African Americans.
- Erosive arthritis and hepatic granuloma formation induced by peptidoglycan polysaccharide in rats is aggravated by prasugrel treatment.
- Health-related quality of life in boys with Duchenne muscular dystrophy: agreement between parents and their sons.
- Platelet glycoprotein IIb. Chromosomal localization and tissue expression.
- Human Platelets differentially concentrate estradiol, estrone and testosterone.
- Childhood gastroesophageal reflux. Neurologic and psychiatric Syndromes mimicked.
- Diagnostic delay in Duchenne's muscular dystrophy.
- Intelligence and EEG studies in families with idiopathic epilepsy.
- Are we still abusing aspirin?
- The role of HLA antibodies in neonatal thrombocytopenia: a prospective study.
- Antibodies against Epstein-Barr nuclear antigen (EBNA) in multiple sclerosis CSF, and two pentapeptide sequence identities between EBNA and myelin basic protein.
- Demyelinating disease after neurologically complicated primary Epstein-Barr virus infection.
- Homologous recombination among three intragene Alu sequences causes an inversion-deletion resulting in the hereditary bleeding disorder Glanzmann Thrombasthenia.
- Cloning of glycoprotein IIIa cDNA from human erythroleukemia cells and localization of the gene to chromosome 17.
- Human Platelets and megakaryocytes contain alternately spliced glycoprotein IIb mRNAs.
- Biogenesis of the Platelet receptor for fibrinogen: evidence for separate precursors for glycoproteins IIb and IIIa.
- Physical linkage of the genes for Platelet membrane glycoproteins IIb and IIIa.
- Clinical problem-solving. Through thick and thin.
- Integrin-dependent control of translation: engagement of integrin alphaIIbbeta3 regulates synthesis of proteins in activated human Platelets.
- Overexpression of cyclin D1 in the Dami megakaryocytic cell line causes growth arrest.
- Talin distribution and phosphorylation in thrombin-activated Platelets.
- Induction of beta3-integrin gene expression by sustained activation of the Ras-regulated Raf-MEK-extracellular signal-regulated kinase signaling pathway.
- Molecular genotyping of fetal Platelet antigens with uncultured amniocytes.
- Glanzmann Thrombasthenia. Cooperation between sequence variants in cis during splice site selection.
- VAMP8/endobrevin is overexpressed in hyperreactive human Platelets: suggested role for Platelet microRNA.
- Clues to the death of an Olympic champion.
- Identification of an abnormal gene for the GPIIIa subunit of the Platelet fibrinogen receptor resulting in Glanzmann's thrombasthenia.
- Quantitative isolation of RNA from human Platelets.
- R to Q amino acid substitution in the GFFKR sequence of the cytoplasmic domain of the integrin IIb subunit in a patient with a Glanzmann's thrombasthenia-like Syndrome.
- Platelet glycoprotein polymorphisms as risk factors for Thrombosis.
- Integrin polymorphisms as risk factors for Thrombosis.
- The minor allele of GP6 T13254C is associated with decreased Platelet activation and a reduced risk of recurrent cardiovascular events and mortality: results from the ...
- Gene frequencies of the five major human Platelet antigens in African American, white, and Korean populations.
- PlA1/A2 polymorphism of Platelet glycoprotein IIIa and risk of cardiovascular disease.
- Coagulation markers predicting cardiac transplant rejection.
- PlA2 polymorphism and efficacy of aspirin.
- Heritability of Platelet function in families with premature coronary artery disease.
- A monoclonal antibody (SZ21) specific for Platelet GPIIIa distinguishes P1A1 from P1A2.
- Refining the treatment of women with unstable angina--a randomized, double-blind, comparative safety and efficacy evaluation of Integrelin versus aspirin in the manage...
- Fibrinogen and prothrombin binding is enhanced to the Pro33 isoform of purified integrin alphaIIbbeta3.
- Quantitation of soluble fibrinogen binding to Platelets by fluorescence-activated flow cytometry.
- Megakaryocyte-targeted synthesis of the integrin beta(3)-subunit results in the phenotypic correction of Glanzmann Thrombasthenia.
- Isolation and characterization of a TATA-less promoter for the human beta 3 integrin gene.
- Genetics of arterial prothrombotic risk States.
- Inherited diseases of Platelet glycoproteins: considerations for rapid molecular characterization.
- Immobilized Platelets support human colon carcinoma cell tethering, rolling, and firm adhesion under dynamic flow conditions.
- Ex vivo cultured megakaryocytes express functional glycoprotein IIb-IIIa receptors and are capable of adenovirus-mediated transgene expression.
- Rapid genotyping of the five major Platelet alloantigens by reverse dot-blot hybridization.
- Human megakaryocytes and Platelets contain the estrogen receptor beta and androgen receptor (AR): testosterone regulates AR expression.
- Localization of a binding site for phosphatidylinositol 4,5-bisphosphate on human profilin.
- Human Platelets contain a glycosylated estrogen receptor beta.
- Platelet FcgammaRIIA His131Arg polymorphism and Platelet function: antibodies to Platelet-bound fibrinogen induce Platelet activation.
- Platelet glycoprotein receptor IIIa polymorphism P1A2 and ischemic stroke risk: the Stroke Prevention in Young Women Study.
- Platelet hyperreactivity generalizes to multiple forms of stimulation.
- Higher prevalence of GPIIIa PlA2 polymorphism in siblings of patients with premature coronary heart disease.
- A polymorphism of a platelet glycoprotein receptor as an inherited risk factor for coronary Thrombosis.
Schools
University of Utah
Baylor College Of Med
Conditions Treated
- Anemia
- Antiphospholipid Syndrome (APS)
- Coagulation Disorders (incl. Hemophilia)
- Deep Vein Thrombosis (DVT)
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Doctors Specialties
- Hematology
- Medical Oncology
- Oncology
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
- Super Doctor
Education
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UCSF -
Baylor College of Medicine -
University of Utah School of Medicine
Hospital
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Thomas Jefferson University Hospital
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1144333097 |
| Last Name Of The Provider | BRAY |
| First Name Of The Provider | PAUL |
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