Physician
Infectious Disease
Dr. Purnell W. Choppin, MD
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Purnell Choppin practices Infectious Disease. He went to medical school at Louisiana State University School of Medicine in New Orleans. He over the years received 2 awards: "Elected Member" and "Whos Who in Medicine and Healthcare". Purnell Choppin is a published physician. He published 101 publications, including: 'The J.I.M. interview. Purnell W. Choppin, MD.'
Publications
- STUDIES OF TWO KINDS OF VIRUS PARTICLES WHICH COMPRISE INFLUENZA A2 VIRUS STRAINS : I. CHARACTERIZATION OF STABLE HOMOGENEOUS SUBSTRAINS IN REACTIONS WITH SPECIFIC ANT...
- Inactivation of enteroviruses by 2,3-dimercaptopropanol (BAL).
- MULTIPLICATION OF A MYXOVIRUS (SV5) WITH MINIMAL CYTOPATHIC EFFECTS AND WITHOUT INTERFERENCE.
- THE MORPHOLOGY OF SV5 VIRUS.
- INTERACTIONS OF ETHER-DISRUPTED INFLUENZA A2 VIRUS WITH ERYTHROCYTES, INHIBITORS, AND ANTIBODIES.
- MULTIPLICATION OF TWO KINDS OF INFLUENZA A2 VIRUS PARTICLES IN MONKEY KIDNEY CELLS.
- ON THE EMERGENCE OF INFLUENZA VIRUS FILAMENTS FROM HOST CELLS.
- PNEUMONIA CAUSED BY TETRACYCLINE-RESISTANTPNEUMOCOCCI.
- Attachment and penetration of influenza virus.
- Plaque formation by influenza A2 virus in monkey kidney cells.
- Heterogeneity of Coxsackie B4 virus: two kinds of particles which differ in antibody sensitivity, growth rate, and plaque size.
- Two kinds of particles with contrasting properties in influenza A virus strains from the 1957 pandemic.
- On the role of virus sulfhydryl groups in the attachment of enteroviruses to erythrocytes.
- Studies of two kinds of virus particles which comprise influenza A2 virus strains. II. Reactivity with virus inhibitors in normal sera.
- The inactivation of enterovirus infectivity by the sulfhydryl reagent p-chloromercuribenzoate.
- Studies of two kinds of virus particles which comprise influenza A2 virus strains. III. Morphological characteristics: independence to morphological and functional tra...
- The surface structure of influenza virus filaments.
- Immunological characteristics of N.Y. strains of influenza A virus from the 1957 pandemic.
- The J.I.M. interview. Purnell W. Choppin, MD.
- The Howard Hughes Medical Institute and science in Central Europe, the Baltics and the former Soviet Union.
- The Howard Hughes Medical Institute.
- Immunological studies of the functions of paramyxovirus glycoproteins.
- Specific inhibition of paramyxovirus and myxovirus replication by oligopeptides with amino acid sequences similar to those at the N-termini of the F1 or HA2 viral poly...
- Role of paramyxovirus glycoproteins in the interactions between viral and cell membranes.
- The polypeptides of canine distemper virus: synthesis in infected cells and relatedness to the polypeptides of other morbilliviruses.
- Identification of a second protein (M2) encoded by RNA segment 7 of influenza virus.
- Influenza B virus RNA segment 8 codes for two nonstructural proteins.
- Isolation of paramyxoviruses from patients with chronic neurologic diseases.
- The functions and inhibition of the membrane glycoproteins of paramyxoviruses and myxoviruses and the role of the measles virus M protein in subacute sclerosing panenc...
- Measles-virus proteins in the brain tissue of patients with subacute sclerosing panencephalitis: absence of the M protein.
- Measles virus and chronic neurological diseases.
- Enhanced yields of measles virus from cultured cells.
- Studies on the helical nucleocapsid of influenza virus.
- Function of cytoplasmic fibers in syncytia.
- The role of viral glycoproteins in adsorption, penetration, and pathogenicity of viruses.
- Sequences of mRNAs derived from genome RNA segment 7 of influenza virus: colinear and interrupted mRNAs code for overlapping proteins.
- Effect of vanadate on intracellular distribution and function of 10-nm filaments.
- Functions of surface glycoproteins of myxoviruses and paramyxoviruses and their inhibition.
- Importance of antibodies to the fusion glycoprotein of paramyxoviruses in the prevention of spread of infection.
- Oligopeptides that specifically inhibit membrane fusion by paramyxoviruses: studies on the site of action.
- Tumorigenicity of cell lines with altered lipid composition.
- Studies on the synthesis of the influenza V virus NB glycoprotein.
- Membrane proteins and virus virulence.
- The gene structure and replication of influenza virus.
- Enhancement of membrane-fusing activity of sendai virus by exposure of the virus to basic pH is correlated with a conformational change in the fusion protein.
- A previously unrecognized influenza B virus glycoprotein from a bicistronic mRNA that also encodes the viral neuraminidase.
- Fusion of Sendai virus with liposomes: dependence on the viral fusion protein (F) and the lipid composition of liposomes.
- Complete nucleotide sequence of the neuraminidase gene of influenza B virus.
- In vitro assembly of the nonglycosylated membrane protein (M) of Sendai virus.
- Sequence of RNA segment 7 of the influenza B virus genome: partial amino acid homology between the membrane proteins (M1) of influenza A and B viruses and conservation...
- the relationship of conformational changes in the Sendai virus nucleocapsid to proteolytic cleavage of the NP polypeptide.
- Inhibition of the neuraminidase of paramyxoviruses by halide ions: a possible means of modulating the two activities of the HN protein.
- Activation of the Sendai virus fusion protein (f) involves a conformational change with exposure of a new hydrophobic region.
- Conformation of the helical nucleocapsids of paramyxoviruses and vesicular stomatitis virus: reversible coiling and uncoiling induced by changes in salt concentration.
- Mapping of the two overlapping genes for polypeptides NS1 and NS2 on RNA segment 8 of influenza virus genome.
- In vitro synthesis of structural and nonstructural proteins of Sendai and SV5 viruses.
- Failure to detect measles virus proteins in brain tissue of patients with multiple sclerosis.
- A ninth unique influenza virus-coded polypeptide.
- Analysis of Sendai virus mRNAs with cDNA clones of viral genes and sequences of biologically important regions of the fusion protein.
- The length of the helical nucleocapsid of Newcastle disease virus.
- The RNAs of infective and incomplete influenza virions grown in MDBK and HeLa cells.
- Influenza virus structural and nonstructural proteins in infected cells and their plasma membranes.
- Proteins and glycoproteins of paramyxoviruses: a comparison of simian virus 5, Newcastle disease virus, and Sendai virus.
- Replication of influenza virus in a continuous cell line: high yield of infective virus from cells inoculated at high multiplicity.
- Cell-fusing activity of visna virus particles.
- Plaque assay of Visna virus using a secondary cellular overlay as an indicator.
- Proteolytic cleavage by plasmin of the HA polypeptide of influenza virus: host cell activation of serum plasminogen.
- Isolation and purification of the envelope proteins of Newcastle disease virus.
- The proteins of visna virus.
- Proteolytic cleavage of subunits of the nucleocapsid of the paramyxovirus simian virus 5.
- Identification of biological activities of paramyxovirus glycoproteins. Activation of cell fusion, hemolysis, and infectivity of proteolytic cleavage of an inactive pr...
- Organization of the lipid phase in viral membranes. Effects of independent variation of the lipid and the protein composition.
- The sense of the helix of paramyxovirus nucleocapsids.
- Possible mechanisms in the pathogenesis of "postinfectious" encephalomyelitis.
- Parainfluenza virus surface projections: glycoproteins with haemagglutinin and neuraminidase activities.
- Glycolipid content of vesicular stomatitis virus grown in baby hamster kidney cells.
- The proteins of the parainfluenza virus SV5. II. The carbohydrate content and glycoproteins of the virion.
- Nucleocapsid protein subunits of simian virus 5, Newcastle disease virus, and Sendai virus.
- Glycosphingolipids of plasma membranes of cultured cells and an enveloped virus (SV5) grown in these cells.
- Plasma membrane lipids and parainfluenza virus assembly.
- Phenotypic mixing of envelope proteins of the parainfluenza virus SV5 and vesicular stomatitis virus.
- The proteins of the parainfluenza virus SV5. 1. Separation of virion polypeptides by polyacrylamide gel electrophoresis.
- A comparison of immune cytolysis and virus-induced fusion of sensitive and resistant cell types.
- Lipids of plasma membranes of monkey and hamster kidney cells and of parainfluenza virions grown in these cells.
- Metabolism of lecithin and virus-induced cell fusion.
- Chemical composition of the parainfluenza virus SV5.
- On the role of microtubules in movement and alignment of nuclei in virus-induced syncytia.
- The nucleic acid of the parainfluenza virus SV5.
- Isolation and properties of the helical nucleocapsid of the parainfluenza virus SV5.
- On the role of the response of the cell membrane in determining virus virulence. Contrasting effects of the parainfluenza virus SV5 in two cell types.
- An electron microscopic study of moderate and virulent virus-cell interactions of the parainfluenza virus SV5.
- Effect of actinomycin D and halogenated deoxyuridines on the replication of simian virus 5.
- Adsorption of attenuated and neurovirulent strains of poliovirus to central nervous system tissues.
- Adsorption of attenuated and neurovirulent poliovirus strains to central nervous system tissues of primates.
- Replication of SV5 RNA and the effects of superinfection with poliovirus.
- Studies on pneumonia virus of mice (PVM) in cell culture. II. Structure and morphogenesis of the virus particle.
- Studies on pneumonia virus of mice (PVM) in cell culture. I. Replication in baby hamster kidney cells and properties of the virus.
- Proteolytic cleavage of the hemagglutinin polypeptide of influenza virus. Function of the uncleaved polypeptide HA.
- The hemagglutinating and neuraminidase protein of a paramyxovirus: interaction with neuraminic acid in affinity chromatography.
- Isolation of paramyxovirus glycoproteins. Association of both hemagglutinating and neuraminidase activities with the larger SV5 glycoprotein.
Doctors Specialties
- Internal Medicine
- Infectious Disease
Accepted Insurances
Awards
- Elected Member
- Whos Who in Medicine and Healthcare
Education
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Louisiana State University School of Medicine in New Orleans
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