University of Oklahoma Health Sciences Center
Rheumatology
Dr. R H. Scofield, MD
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Doctor R H. Scofield, MD works in the field of Rheumatology. He attended University of Texas Southwestern Medical School. R H. Scofield is a published doctor and has 100 publications published. The lastest was: 'Previous diagnosis of Sjgren's Syndrome as rheumatoid arthritis or systemic lupus erythematosus.'
Publications
- Interaction between innate immunity and Ro52-induced antibody causes Sjögren's syndrome-like disorder in mice.
- Biological therapy and dentistry: a review paper.
- Passive transfer of antibodies to the linear epitope 60 kD Ro 273-289 induces features of Sjögren's syndrome in naïve mice.
- Preferential association of a functional variant in complement receptor 2 With antibodies to double-stranded DNA.
- Antibody-secreting cell specificity in labial salivary Glands reflects clinical presentation and serology in sjögren's syndrome patients.
- The IRF5-TNPO3 association with systemic lupus erythematosus (SLE) has two components that other autoimmune Disorders variably share.
- Two Functional Lupus-Associated BLK Promoter Variants Control Cell-Type- and Developmental-Stage-Specific Transcription.
- Genome-Wide DNA Methylation Patterns in Naive CD4+ T Cells From Patients With Primary Sjögren's Syndrome.
- Prolidase deficiency breaks tolerance to lupus-associated antigens.
- Variants at multiple loci implicated in both innate and adaptive immune responses are associated With Sjögren's syndrome.
- Genome-wide DNA methylation patterns in naïve CD4(+) T cells from patients With primary Sjögren's syndrome.
- Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression.
- The CCR5 delta 32 polymorphism (rs333) is not associated with Sjögren's syndrome or Type 1 Diabetes in Colombians.
- Comparison of the American-European Consensus Group Sjogren's syndrome classification criteria to newly proposed American College of Rheumatology criteria in a large, ...
- Autoimmunity and infection in Sjögren's syndrome.
- Variable Association of Reactive Intermediate Genes With Systemic Lupus Erythematosus in Populations With Different African Ancestry.
- Immunization With 60 kD Ro peptide produces different stages of pre-clinical autoimmunity in a Sjögren's syndrome-model among multiple strains of inbred mice.
- MicroRNA-3148 Modulates Allelic Expression of Toll-Like Receptor 7 Variant Associated With Systemic Lupus Erythematosus.
- Admixture Mapping in Lupus Identifies Multiple Functional Variants Within IFIH1 Associated With Apoptosis, Inflammation, and Autoantibody Production.
- Excess Female Siblings and Male Fetal Loss in Families With Systemic Lupus Erythematosus.
- Comparison of autoantibody specificities between traditional and bead-based assays in a large, diverse collection of patients With systemic lupus erythematosus and fam...
- Mapping susceptibility gene in systemic lupus erythematosus.
- Two independent functional risk haploTypes in TNIP1 are associated with systemic lupus erythematosus.
- Induction of anti-Ro60/anti-La by immunisation With spectrin and induction of anti-spectrin by immunisation With Ro60 and 4-hydroxy-2-nonenal-modified Ro60 immunisation.
- Common artifacts and mistakes made in electrophoresis.
- A brief review of other notable protein detection methods on acrylamide gels.
- Spicy SDS-PAGE Gels: Curcumin/Turmeric as an Environment-Friendly Protein Stain.
- Accelerated Coomassie Blue Staining and Destaining of SDS-PAGE Gels With Application of Heat.
- Long-Term, Buffer-Less, Wet Gel Storage in Non-sealed Polyethylene Bags.
- Extraction of proteins from gels: a brief review.
- Native flatbed isoelectric focusing for determining antibody clonoType distribution.
- Sex-specific differences in the relationship between genetic susceptibility, T cell DNA demethylation and lupus flare severity.
- Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men With systemic lupus erythematosus.
- Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as Susceptibility Loci for Systemic Lupus Erythematosus in a Large-Scale Multiracial Replication Study.
- A functional haploType of UBE2L3 confers risk for systemic lupus erythematosus.
- Putative sequences on Ro60 three-dimensional structure accessible for 4-hydroxy-2-nonenal (HNE) modification compared to in vitro HNE modification of Ro60 sequences.
- Vitamin D deficiency is associated With an increased autoimmune response in healthy individuals and in patients With systemic lupus erythematosus.
- Degree of modification of Ro60 by the Lipid peroxidation by-product 4-hydroxy-2-nonenal may differentially induce Sjögren syndrome or systemic lupus eryth...
- Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort.
- Curcumin does not bind or intercalate into DNA and a note on the gray side of curcumin.
- A novel modular antigen delivery system for immuno targeting of human 6-sulfo LacNAc-positive blood dendritic cells (SlanDCs).
- An overview of Western blotting for determining antibody specificities for immunohistochemistry.
- Problems With multiple use of transfer buffer in protein electrophoretic transfer.
- The place of William Osler in the description of systemic lupus erythematosus.
- Oral administration of heat-solubilized curcumin for potentially increasing curcumin bioavailability in experimental animals.
- Bubbling hookah smoke through heat-solubilized curcumin/turmeric and incorporation of the curry spice as an additive or filter in cigarettes to minimize tobacco smoke-...
- Genetics of systemic lupus erythematosus and Sjögren's syndrome.
- High-density genotyping of STAT4 reveals multiple haplotypic associations With systemic lupus erythematosus in different racial groups.
- Heat-solubilized curcumin should be considered in clinical trials for increasing bioavailability.
- Detection of La/SS-B by western blot using nanogold-tagged antibodies and silver enhancement.
- A brief review of other notable protein detection methods on blots.
- Introduction to protein blotting.
- Tryptic peptide purification using polyvinylidene difluoride membrane for matrix-assisted laser desorption ionization time of flight mass spectrometry.
- Affinity immunoblotting for analysis of antibody clonoType distribution in a lupus patient developing anti-Ro 60 over time.
- Nonelectrophoretic bidirectional transfer of a single SDS-PAGE gel With multiple antigens to obtain 12 immunoblots.
- A miniaturized blotting system for simultaneous detecting of different autoantibodies.
- Ultrarapid electrophoretic transfer of high and low molecular weight proteins using heat.
- Grid-immunoblotting.
- A brief review of other notable protein blotting methods.
- Phosphoprotein detection on protein electroblot using a phosphate-specific fluorophore.
- Whole and strip nitrocellulose membrane as well as a new-line-immunoblotting of antigen using the chemiluminescence technique.
- Protein stains to detect antigen on membranes.
- Chronic lymphocytic leukemia cells recognize conserved epitopes associated With apoptosis and oxidation.
- Klinefelter's syndrome (47,XXY) in male systemic lupus erythematosus patients: support for the notion of a gene-dose effect from the X chromosome.
- Autoantibody prevalence and lupus characteristics in a unique African American population.
- Oral Manifestations of Sjögren's syndrome.
- Common variants Within MECP2 confer risk of systemic lupus erythematosus.
- 13-cis-Retinoic acid (isotretinoin) unmasking of clinical polycystic ovary syndrome.
- Improving the solubility and pharmacological efficacy of curcumin by heat treatment.
- Oral glucosamine in doses used to treat osteoarthritis worsens insulin resistance.
- Horizons in Sjögren's syndrome genetics.
- Epstein-Barr virus and systemic lupus erythematosus.
- Milk-alkali syndrome in pre-eclamptic pregnancy: report of a patient and evaluation of albumin-corrected Calcium in pre-eclamptic pregnancies.
- Oxidatively modified autoantigens in autoimmune Diseases.
- Milk-alkali syndrome: a historical review and description of the modern version of the syndrome.
- Western blotting.
- A nonsense mutation of PEPD in four Amish children With prolidase deficiency.
- Prolidase deficiency and the biochemical assays used in its diagnosis.
- Immunization With short peptides from the 60-kDa Ro antigen recapitulates the serological and pathological findings as well as the salivary gland dysfunction of Sjogre...
- Linkage at 5q14.3-15 in multiplex systemic lupus erythematosus pedigrees stratified by autoimmune thyroid Disease.
- Modification of lupus-associated 60-kDa Ro protein With the lipid oxidation product 4-hydroxy-2-nonenal increases antigenicity and facilitates epitope spreading.
- Determination of prolidase activity using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
- Mechanized syringe homogenization of human and animal tissues.
- A candidate region on 11p13 for systemic lupus erythematosus: a linkage identified in African-American families.
- Mapping the systematic lupus erythematosus susceptibility genes.
- Development of autoantibodies before the clinical onset of systemic lupus erythematosus.
- The genetics of primary Sjögren's syndrome.
- Thrombocytopenia identifies a severe familial phenoType of systemic lupus erythematosus and reveals genetic linkages at 1q22 and 11p13.
- Evidence for a susceptibility gene (SLEH1) on chromosome 11q14 for systemic lupus erythematosus (SLE) families With hemolytic anemia.
- Hashimoto's Thyroiditis presenting as bilateral knee arthropathy.
- Extraction of nucleic acid fragments from gels.
- Evidence for a susceptibility gene, SLEV1, on chromosome 17p13 in families With vitiligo-related systemic lupus erythematosus.
- Non-surgical therapy of primary Hyperparathyroidism.
- Pellet pestle homogenization of agarose gel slices at 45 degrees C for deoxyribonucleic acid extraction.
- Role of viruses in systemic lupus erythematosus and Sjögren syndrome.
- Immunization as a model for systemic lupus erythematosus.
- Immunization of mice With human 60-kd Ro peptides results in epitope spreading if the peptides are highly homologous between human and mouse.
- Induction of autoimmunity by multivalent immunodominant and subdominant T cell determinants of La (SS-B).
- Previous diagnosis of Sjögren's Syndrome as rheumatoid arthritis or systemic lupus erythematosus.
Schools
University of Texas Southwestern Medical Center At Dallas
University Okla Health Scis Center
Conditions Treated
- Adrenal Incidentaloma
- Adrenal Insufficiency
- Calcium Metabolism Disorders
- Diabetes Type 1
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Doctors Specialties
- Rheumatology
Accepted Insurances
Education
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University of Oklahoma Health Sciences Center -
University Hospital & Clinics -
University of Texas Southwestern Medical School
Drug Facts
| NPI NUMBER | 1821067562 | |
| NPPES Provider LastName | SCOFIELD | |
| NPPES Provider FirstName | R | |
| NPPES Provider ZIPCode | 731043252 | |
| NPPES Provider State | OK | |
| Specialty Description | Endocrinology | |
| Total Claim Count | 574.0 | |
| Distinct Opioid Count | 1.0 | |
| Opioid Claim Count | 12.0 | |
| Percent Opioid Claims | 2.09 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1821067562 |
| Last Name Of The Provider | SCOFIELD |
| First Name Of The Provider | R |
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