Professor of Radiology, Massachusetts General Hospital
Radiology
Dr. Ralph Weissleder, MD
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Doctor Ralph Weissleder, MD works in the field of Radiology. He received awards:"Elected Member". Doctor Ralph Weissleder, MD is a published MD. He published 102 publications, including: 'SCS macrophages suppress melanoma by restricting tumor-derived vesicle-B cell interactions.' Ralph Weissleder, MD accepts all Medicare patients.
Publications
- Predicting therapeutic nanomedicine efficacy using a companion magnetic resonance imaging nanoparticle.
- Fluorescence Polarization Based Nucleic Acid Testing for Rapid and Cost-Effective Diagnosis of Infectious Disease.
- Imaging the beating heart in the mouse using intravital microscopy techniques.
- Targeting Interleukin-1β Reduces Leukocyte Production After Acute Myocardial Infarction.
- Imaging Macrophage and Hematopoietic Progenitor Proliferation in Atherosclerosis.
- Lp-PLA2 Antagonizes Left Ventricular Healing After Myocardial Infarction by Impairing the Appearance of Reparative Macrophages.
- Acoustic purification of extracellular microvesicles.
- Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis.
- Interleukin-3 amplifies Acute inflammation and is a potential therapeutic target in sepsis.
- Macrophages retain hematopoietic stem cells in the spleen via VCAM-1.
- Population dynamics of islet-infiltrating cells in autoimmune diabetes.
- Noninvasive mapping of pancreatic inflammation in recent-onset type-1 diabetes patients.
- Combined MEK and PI3K inhibition in a mouse model of pancreatic Cancer.
- Nanotechnology.
- Exploring alternative ovarian Cancer biomarkers using innovative nanotechnology strategies.
- Imaging cellular distribution of bcl inhibitors using small molecule drug conjugates.
- Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin.
- Ischemic Stroke Activates Hematopoietic Bone Marrow Stem Cells.
- 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Enables the Detection of Recurrent Same-Site Deep Vein Thrombosis by Illuminating Recently Form...
- Increased Microvascularization and Vessel Permeability Associate with Active Inflammation in Human Atheromata.
- Magnetic sensing technology for molecular analyses.
- Ultrafluorogenic Coumarin-Tetrazine Probes for Real-Time Biological Imaging.
- Silencing of CCR2 in myocarditis.
- Chronic variable stress activates hematopoietic stem cells.
- Endoscopic photoconversion reveals unexpectedly broad leukocyte trafficking to and from the gut.
- Differential Contribution of Monocytes to Heart Macrophages in Steady-State and After Myocardial Infarction.
- In Vivo Imaging of Multidrug Resistance Using a Third Generation MDR1 Inhibitor.
- Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis.
- Red Si-rhodamine drug conjugates enable imaging in GFP cells.
- Building Blocks for the Construction of Bioorthogonally Reactive Peptides via Solid-Phase Peptide Synthesis.
- Efficient Acid-Catalyzed (18) F/(19) F Fluoride Exchange of BODIPY Dyes.
- Ly-6Chigh Monocytes Depend on Nr4a1 to Balance both Inflammatory and Reparative Phases in the Infarcted Myocardium.
- Extracellular Vesicles Modulate the Glioblastoma Microenvironment via a Tumor Suppression Signaling Network Directed by miR-1.
- Platinum Compounds for High-Resolution In Vivo Cancer Imaging.
- Magnetic Ligation Method for Quantitative Detection of MicroRNAs.
- Effect of Small Molecule Modification on Single Cell Pharmacokinetics of PARP Inhibitors.
- Cancer cell profiling by barcoding allows multiplexed protein analysis in fine-needle aspirates.
- Imaging macrophages with nanoparticles.
- Innate Response Activator B Cells Aggravate Atherosclerosis by Stimulating TH1 Adaptive Immunity.
- Accurate prediction of nodal status in preoperative patients with pancreatic ductal adenocarcinoma using next-gen nanoparticle.
- In vivo silencing of the transcription factor IRF5 reprograms the macrophage phenotype and improves infarct healing.
- Fluorescent Exendin-4 Derivatives for Pancreatic β-Cell Analysis.
- Ascites analysis by a microfluidic chip allows tumor-cell profiling.
- Magnetic Nanosensor for Detection and Profiling of Erythrocyte-Derived Microvesicles.
- Molecular characterization of scant lung tumor cells using iron-oxide nanoparticles and micro-nuclear magnetic resonance.
- A photoactivatable drug-caged fluorophore conjugate allows direct quantification of intracellular drug transport.
- Local proliferation dominates lesional macrophage accumulation in atherosclerosis.
- Bioorthogonal Approach to Identify Unsuspected Drug Targets in Live Cells.
- Nanoparticle PET-CT Detects Rejection and Immunomodulation in Cardiac Allografts.
- Targeting cathepsin E in pancreatic Cancer by a small molecule allows in vivo detection.
- Miniaturized nuclear magnetic resonance platform for detection and profiling of circulating tumor cells.
- A magneto-DNA nanoparticle system for rapid detection and phenotyping of bacteria.
- BODIPY-Tetrazine Derivatives as Superbright Bioorthogonal Turn-on Probes.
- A Pretargeted PET Imaging Strategy Based on Bioorthogonal Diels-Alder Click Chemistry.
- Monocyte-Directed RNAi Targeting CCR2 Improves Infarct Healing in Atherosclerosis-Prone Mice.
- Magnetic barcode assay for genetic detection of pathogens.
- Comparison of select Cancer biomarkers in human circulating and bulk tumor cells using magnetic nanoparticles and miniaturized micro-NMR system.
- ?Hall Chip for Sensitive Detection of Bacteria.
- Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo.
- Nano-SAR Development for Bioactivity of Nanoparticles with Considerations of Decision Boundaries.
- Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells.
- Angiotensin II Drives the Production of Tumor-Promoting Macrophages.
- Polymeric Nanoparticle PET/MR Imaging Allows Macrophage Detection in Atherosclerotic Plaques.
- Painting blood vessels and atherosclerotic plaques with an adhesive drug depot.
- The Histone Deacetylase SIRT6 Is a Tumor Suppressor that Controls Cancer Metabolism.
- Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy.
- Implantable microenvironments to attract hematopoietic stem/Cancer cells.
- Photocleavable DNA barcode-antibody conjugates allow sensitive and multiplexed protein analysis in single cells.
- Inflammation modulates murine venous Thrombosis resolution in vivo: assessment by multimodal fluorescence molecular imaging.
- Selective Factor XIIa Inhibition Attenuates Silent Brain Ischemia: Application of Molecular Imaging Targeting Coagulation Pathway.
- Motion compensation using a suctioning stabilizer for intravital microscopy.
- Improved intravital microscopy via synchronization of respiration and holder stabilization.
- Dual Imaging and Photoactivated Nanoprobe for Controlled Cell Tracking.
- Noise suppressed, multifocus image fusion for enhanced intraoperative navigation.
- Efficient (18)F-Labeling of Synthetic Exendin-4 Analogues for Imaging Beta Cells.
- Mechanism of Magnetic Relaxation Switching Sensing.
- Ultrasensitive Clinical Enumeration of Rare Cells ex Vivo Using a Micro-Hall Detector.
- On-chip bioorthogonal chemistry enables immobilization of in situ modified nanoparticles and small molecules for label-free monitoring of protein binding and reaction ...
- Bioorthogonal imaging of aurora kinase A in live cells.
- Microfluidic Cell Sorter (üFCS) for On-chip Capture and Analysis of Single Cells.
- Multifunctional nanoagent for thrombus-targeted fibrinolytic therapy.
- A Magnetic Gram Stain for Bacterial Detection.
- Myocardial infarction accelerates atherosclerosis.
- Molecular imaging of fibrin deposition in Deep vein thrombosis using fibrin-targeted near-infrared fluorescence.
- Sensitive and direct detection of circulating tumor cells by multimarker µ-nuclear magnetic resonance.
- Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism.
- Regulation of monocyte functional heterogeneity by miR-146a and Relb.
- Mapping molecular agents distributions in whole mice hearts using born-normalized optical projection tomography.
- In vivo imaging of drug-induced mitochondrial outer membrane permeabilization at single cell resolution.
- Establishment and characterization of a novel chordoma cell line: CH22.
- Reactive polymer enables efficient in vivo bioorthogonal chemistry.
- Demyelinating Diseases: myeloperoxidase as an imaging biomarker and therapeutic target.
- Orthogonal Amplification of Nanoparticles for Improved Diagnostic Sensing.
- Single reporter for targeted multimodal in vivo imaging.
- Imaging Therapeutic PARP Inhibition In Vivo through Bioorthogonally Developed Companion Imaging Agents.
- Molecular imaging of innate immune cell function in transplant rejection.
- Arterial and Aortic valve calcification abolished by elastolytic cathepsin S deficiency in chronic renal disease.
- SCS macrophages suppress melanoma by restricting tumor-derived vesicle-B cell interactions.
- Integrated Magneto-Electrochemical Sensor for Exosome Analysis.
- Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy.
- The use of (18)F-2-fluorodeoxyglucose (FDG) to label antibody fragments for immuno-PET of pancreatic Cancer.
Schools
RuprechtKarlsUniversitaet Heidelberg Medizinische Gesamtfakultat
Massachusetts General Hospital
Procedures Preformed
- Bile Duct Procedure
- Bile Duct Surgery
- Biopsy
- Gastric Tube Insertion
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Conditions Treated
- Abdominal Aortic Aneurysm (AAA)
- Acute Deep Vein Thrombosis (DVT)
- Acute Venous Embolism Thrombosis
- Biliary Disorders
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Doctors Specialties
- Diagnostic Radiology
- Radiology
Accepted Insurances
- Great West Healthcare-Cigna PPO
- MultiPlan PPO
- PHCS Network PPO
- Tufts PPO
Awards
- Elected Member
Education
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Massachusetts General Hospital -
Ruprecht Karl University Faculty of Medicine
Hospital
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Massachusetts General Hospital
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1417948498 |
| Last Name Of The Provider | WEISSLEDER |
| First Name Of The Provider | RALPH |
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