General Surgeon in Superior Medical Care
General Surgery
Dr. Ravi Chari, MD
|
|
Give Review
Dr. Ravi Chari works in the field of General Surgery. He went to University of Cincinnati College of Medicine. He received 1 awards: "Fellow (FACS)". Ravi Chari is also a published MD. He has 30 publication published. The most recent publication is: Folate-maytansinoids: target-selective drugs of low molecular weight.
Publications
- Evaluation of Targets for Maytansinoid ADC Therapy Using a Novel Radiochemical Assay.
- The role of halogen substitution in classical cannabinoids: a CB1 pharmacophore model.
- World Antibody Drug Conjugate Summit Europe: February 21-23, 2011; Frankfurt, Germany.
- Magnetically aligned bicelles to study the orientation of lipophilic ligands in membrane bilayers.
- Pharmacophoric requirements for the cannabinoid side chain. Probing the cannabinoid receptor subsite at C1'.
- The development of antibody delivery systems to target Cancer with highly potent maytansinoids.
- Design of antibody-maytansinoid conjugates allows for efficient detoxification via Liver metabolism.
- The antileukemic efficacy of an immunotoxin composed of a monoclonal anti-Thy-1 antibody disulfide linked to the ribosome-inactivating protein gelonin.
- Maytansinoid-antibody conjugates induce mitotic arrest by suppressing microtubule dynamic instability.
- Maytansine and cellular metabolites of antibody-maytansinoid conjugates strongly suppress microtubule dynamics by binding to microtubules.
- Folate-maytansinoids: target-selective drugs of low molecular weight.
- Eradication of large colon tumor xenografts by targeted deLivery of maytansinoids.
- Immunoconjugates containing novel maytansinoids: promising antiCancer drugs.
- Enhancement of the selectivity and antitumor efficacy of a CC-1065 Analogue through immunoconjugate formation.
- Synthesis and biological evaluation of antibody conjugates of phosphate prodrugs of cytotoxic DNA alkylators for the targeted treatment of Cancer.
- Antibody conjugate therapeutics: challenges and potential.
- A novel pathway for maytansinoid release from thioether linked antibody-drug conjugates (ADCs) under oxidative conditions.
- Synthesis and evaluation of hydrophilic linkers for antibody-maytansinoid conjugates.
- Disulfide-linked antibody-maytansinoid conjugates: optimization of in vivo activity by varying the steric hindrance at carbon atoms adjacent to the disulfide linkage.
- Cantuzumab mertansine, a maytansinoid immunoconjugate directed to the CanAg antigen: a phase I, pharmacokinetic, and biologic correlative study.
- Tumor-specific novel taxoid-monoclonal antibody conjugates.
- Antibody-maytansinoid conjugates designed to bypass multidrug resistance.
- Targeting HER2-positive breast Cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate.
- Targeted Cancer therapy: conferring specificity to cytotoxic drugs.
- Folate receptor-specific antitumor activity of EC131, a folate-maytansinoid conjugate.
- Semisynthetic maytansine Analogues for the targeted treatment of cancer.
- Synthesis and biological evaluation of novel taxoids designed for targeted deLivery to tumors.
- Synthesis of taxoids with improved cytotoxicity and solubility for use in tumor-specific deLivery.
- Synthesis of potent taxoids for tumor-specific deLivery using monoclonal antibodies.
Schools
University of Cincinnati Main Campus
Huron Hospital Cleveland Clinic
Rush Presby St Luke39s M C
Procedures Preformed
- Appendectomy, Laparoscopic
- Appendectomy, Open
- Biopsy of Breast
- Breast Reconstruction
- View All
Conditions Treated
- Abdominal Pain
- Anal and Rectal Cancer
- Anal Fissure
- Anorectal Abscess
- View All
Doctors Specialties
- General Surgery
Accepted Insurances
Awards
- Fellow (FACS)
Education
-
Rush University Medical Center -
University of Cincinnati College of Medicine
Hospital
-
St. John Medical Center
Drug Facts
| NPI NUMBER | 1093779639 | |
| NPPES Provider LastName | CHARI | |
| NPPES Provider FirstName | RAVI | |
| NPPES Provider ZIPCode | 440351469 | |
| NPPES Provider State | OH | |
| Specialty Description | General Surgery | |
| Total Claim Count | 499.0 | |
| Distinct Opioid Count | 2.0 | |
| Opioid Claim Count | 75.0 | |
| Percent Opioid Claims | 15.03 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1093779639 |
| Last Name Of The Provider | CHARI |
| First Name Of The Provider | RAVI |
| View All |
Similar Doctors
|
|
Dr. Keith Warner, MD
 This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Robert C. Warren, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. John Costin, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Ramon Malaya, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Carl M. Yood, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. J Poblete, MD |
|
|
Dr. Daniel P. Donato, MD |