Professor, Pathology, Stanford University Medical Center
Pathology
Dr. Raymond A. Sobel, MD
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Raymond A. Sobel works in the field of Pathology. He studied medicine at University of California San Francisco School of Medicine. University of California San Francisco School of Medicine is one of the top medical schools in the US. University of California San Francisco School of Medicine has a rank of 3 in research and a 3 in primary care Raymond A. Sobel is also a published doctor. He has 65 publication published. The most recent publication is: B-cell very late antigen-4 deficiency reduces leukocyte recruitment and susceptibility to central nervous system autoimmunity.
Publications
- Tim-1 is essential for induction and maintenance of IL-10 in regulatory B cells and their regulation of tissue inflammation.
- B-cell very late antigen-4 deficiency reduces leukocyte recruitment and susceptibility to central nervous system autoimmunity.
- Uncovering Cryptic Glycan Markers in Multiple Sclerosis (MS) and Experimental Autoimmune Encephalomyelitis (EAE).
- MHC class II-dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies.
- Defective sphingosine 1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation.
- Amyloid fibrils composed of hexameric peptides attenuate neuroinflammation.
- Aberrant mitochondrial fission in neurons induced by protein kinase C{delta} under oxidative stress conditions in vivo.
- Peroxisome proliferator-activated receptor delta limits the expansion of pathogenic Th cells during central nervous system autoimmunity.
- Tim-3/galectin-9 pathway: regulation of Th1 immunity through promotion of CD11b+Ly-6G+ myeloid cells.
- Expression of varicella-zoster virus immediate-early regulatory protein IE63 in neurons of latently infected human sensory ganglia.
- Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes.
- Chemokine-like receptor-1 expression by central nervous system-infiltrating leukocytes and involvement in a model of autoimmune demyelinating disease.
- Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1- and TH17-mediated autoimmunity.
- Comparative efficacies of lipid-complexed amphotericin B and liposomal amphotericin B against coccidioidal meningitis in rabbits.
- IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells.
- A novel unifying hypothesis of multiple sclerosis.
- TIM-4 expressed on APCs induces T cell expansion and survival.
- Anti-Ca2+ channel antibody attenuates Ca2+ currents and mimics cerebellar ataxia in vivo.
- Sustained pharmacological inhibition of deltaPKC protects against hypertensive encephalopathy through prevention of blood-brain barrier breakdown in rats.
- Neuropathology--for the living and the future.
- Type II monocytes modulate T cell-mediated central nervous system autoimmune disease.
- Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function.
- I kappa B kinase 2/beta deficiency controls expansion of autoreactive T cells and suppresses experimental autoimmune encephalomyelitis.
- Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation.
- Comparison of itraconazole and fluconazole treatments in a murine model of coccidioidal meningitis.
- Peroxisome proliferator-activated receptor (PPAR)alpha expression in T cells mediates gender differences in development of T cell-mediated autoimmunity.
- Anti-viral T-cell immunity+anti-CNS autoantibody=a model for human acute disseminated encephalomyelitis or multiple sclerosis relapse?
- Heme oxygenase-1 and carbon monoxide suppress autoimmune neuroinflammation.
- Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells.
- Myelin oligodendrocyte glycoprotein-specific T and B cells cooperate to induce a Devic-like disease in mice.
- The autoimmune diabetes locus Idd9 regulates development of type 1 diabetes by affecting the homing of islet-specific T cells.
- Immunomodulatory synergy by combination of atorvastatin and glatiramer acetate in treatment of CNS autoimmunity.
- Monoclonal antibodies to distinct regions of human myelin proteolipid protein simultaneously recognize central nervous system myelin and neurons of many vertebrate spe...
- Lipid microarrays identify key mediators of autoimmune brain inflammation.
- The ICOS molecule plays a crucial role in the development of mucosal tolerance.
- Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite.
- Cutting edge: CD4+CD25+ regulatory T cells contribute to gender differences in susceptibility to experimental autoimmune encephalomyelitis.
- A suppressive oligodeoxynucleotide enhances the efficacy of myelin cocktail/IL-4-tolerizing DNA vaccination and treats autoimmune disease.
- CD226 is specifically expressed on the surface of Th1 cells and regulates their expansion and effector functions.
- Tim-2 regulates T helper type 2 responses and autoimmunity.
- Axon reactive B cells clonally expanded in the cerebrospinal fluid of patients with multiple sclerosis.
- Immunity to the extracellular domain of Nogo-A modulates experimental autoimmune encephalomyelitis.
- Myelin proteolipid protein-specific CD4+CD25+ regulatory cells mediate genetic resistance to experimental autoimmune encephalomyelitis.
- PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells.
- IL-10 plays an important role in the homeostatic regulation of the autoreactive repertoire in naive mice.
- Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis.
- The diabetes susceptibility locus Idd5.1 on mouse chromosome 1 regulates ICOS expression and modulates murine experimental autoimmune encephalomyelitis.
- Cytokine and inducible nitric oxide synthase mRNA expression during experimental murine cryptococcal meningoencephalitis.
- IFN-inducible protein 10/CXC chemokine ligand 10-independent induction of experimental autoimmune encephalomyelitis.
- Somatic instability of the NF2 gene in schwannomatosis.
- Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis.
- Mild hypothermia inhibits nuclear factor-kappaB translocation in experimental stroke.
- Gene therapy and hypothermia for stroke treatment.
- Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination.
- Efficacy of amphotericin B or itraconazole in a murine model of central nervous system Aspergillus infection.
- A murine model of coccidioidal meningitis.
- Levels of matrix metalloproteinase-9 within cerebrospinal fluid in a rabbit model of coccidioidal meningitis and vasculitis.
- Development of a murine model of cerebral aspergillosis.
- Efficacy of intravenous liposomal amphotericin B (AmBisome) against coccidioidal meningitis in rabbits.
- Interferon-beta counteracts inflammatory mediator-induced effects on brain endothelial cell tight junction molecules-implications for multiple sclerosis.
- Cytotoxic T lymphocyte antigen-4 (CTLA-4) limits the expansion of encephalitogenic T cells in experimental autoimmune encephalomyelitis (EAE)-resistant BALB/c mice.
- A Novel CMKLR1 Small Molecule Antagonist Suppresses CNS Autoimmune Inflammatory Disease.
- SJL Mice Infected with Acanthamoeba castellanii Develop Central Nervous System Autoimmunity through the Generation of Cross-Reactive T Cells for Myelin Antigens.
- Aspergillus fumigatus Invasion Increases with Progressive Airway Ischemia.
Schools
University of California At San Francisco
Mass Gen Hospital
Moffitt Hospital University Of Ca
Stanford University Hospital
University Ca Davis Med Center
Doctors Specialties
- Neuropathology
- Pathology
Accepted Insurances
Education
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Massachusetts General Hospital -
Stanford University -
UCSF -
University of California Davis -
University of California San Francisco School of Medicine
Hospital
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VA Palo Alto Health Care System -
Stanford Health Care
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