Professor, Laboratory Medicine and Pathology, Mayo Medical School
Pathology
Dr. Rhett P. Ketterling, MD
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Rhett P. Ketterling works in the field of Pathology. He went to medical school at Mayo Medical School. Mayo Medical School is ranked 27/42 in Research/PrimaryCare. Rhett Ketterling has written publications. He has 97 publications published with PubMed. The lastest publication is: 'Transient monosomy 7 in a chronic myelogenous leukemia patient during nilotinib therapy: a case report.'
Publications
- A phase II randomized trial comparing standard and low dose rituximab combined with alemtuzumab as initial treatment of progressive chronic lymphocytic leukemia in old...
- Calreticulin (CALR) variant stratified driver mutational status and prognosis in essential thrombocythemia.
- Azacitidine with or without Entinostat for the treatment of therapy-related myeloid neoplasm: further results of the E1905 North American Leukemia Intergroup study.
- Morphologically Occult Systemic Mastocytosis in Bone Marrow: Clinicopathologic Features and an Algorithmic Approach to Diagnosis.
- Mutations and thrombosis in essential thrombocythemia: prognostic interaction with age and thrombosis history.
- A compendium of cytogenetic abnormalities in myelofibrosis: molecular and phenotypic correlates in 826 patients.
- Genetic determinants of response and survival in momelotinib-treated patients with myelofibrosis.
- Expression of the Chemokine Receptor Gene, CCR8, is Associated With DUSP22 Rearrangements in Anaplastic Large Cell Lymphoma.
- Chromosomal rearrangements and copy number abnormalities of TP63 correlate with p63 protein expression in lung adenocarcinoma.
- Molecular and prognostic correlates of cytogenetic abnormalities in chronic myelomonocytic leukemia: A Mayo Clinic-French Consortium Study.
- Development of an NPM1/MLF1 D-FISH Probe Set for the Detection of t(3;5)(q25;q35) Identified in Patients with Acute Myeloid Leukemia.
- CALR vs JAK2 vs MPL-mutated or triple-negative myelofibrosis: clinical, cytogenetic and molecular comparisons.
- Histiocytoid Sweet syndrome may indicate leukemia cutis: a novel application of fluorescence in situ hybridization.
- ALK-negative anaplastic large cell lymphoma is a genetically heterogeneous disease with widely disparate clinical outcomes.
- Intralymphatic Cutaneous Anaplastic Large Cell Lymphoma/Lymphomatoid Papulosis: Expanding the Spectrum of CD30-positive Lymphoproliferative Disorders.
- Calreticulin mutations and long-term survival in essential thrombocythemia.
- Type 1 versus Type 2 calreticulin mutations in essential thrombocythemia: A collaborative study of 1027 patients.
- Type 1 vs type 2 calreticulin mutations in primary myelofibrosis: differences in phenotype and prognostic impact.
- The number of prognostically detrimental mutations and prognosis in primary myelofibrosis: an international study of 797 patients.
- U2AF1 mutations in primary myelofibrosis are strongly associated with anemia and thrombocytopenia despite clustering with JAK2V617F and normal karyotype.
- Differences in the distribution of cytogenetic subtypes between multiple myeloma patients with and without a family history of monoclonal gammopathy and multiple mye...
- Evaluation of revised IPSS cytogenetic risk stratification and prognostic impact of monosomal karyotype in 783 patients with primary myelodysplastic syndromes.
- Clonally related follicular lymphomas and Langerhans cell neoplasms: expanding the spectrum of transdifferentiation.
- Mayo prognostic model for WHO-defined chronic myelomonocytic leukemia: ASXL1 and spliceosome component mutations and outcomes.
- Chromosomal Rearrangements of 6p25.3 Define a New Subtype of Lymphomatoid Papulosis.
- SETBP1 mutations in 415 patients with primary myelofibrosis or chronic myelomonocytic leukemia (CMML): independent prognostic impact in CMML.
- CSF3R T618I is a highly prevalent and specific mutation in chronic neutrophilic leukemia.
- Atypical generalized eruptive histiocytosis clonally related to chronic myelomonocytic leukemia with loss of Y chromosome.
- Impact of Primary Molecular Cytogenetic Abnormalities and Risk of Progression in Smoldering Multiple Myeloma.
- A Case of Nonleukemic Myeloid Sarcoma With FIP1L1-PDGFRA Rearrangement: An Unusual Presentation of a Rare Disease.
- Spliceosome mutations involving SRSF2, SF3B1, and U2AF35 in chronic myelomonocytic leukemia: Prevalence, clinical correlates, and prognostic relevance.
- Trisomies in multiple myeloma: impact on survival in patients with high-risk cytogenetics.
- SF3B1 mutations are prevalent in myelodysplastic syndromes with ring sideroblasts but do not hold independent prognostic value.
- Clinicopathologic and genetic characterization of follicular lymphomas presenting in the ovary reveals 2 distinct subgroups.
- Microgranular variant of acute promyelocytic leukemia with normal conventional cytogenetics, negative PML/RARA FISH and positive PML/RARA transcripts by RT-PCR.
- Correlation of CYP2B6, CYP2C19, ABCC4 and SOD2 genotype with outcomes in allogeneic blood and marrow transplant patients.
- A Case of Hairy Cell Leukemia With CCND1-IGH@ Translocation: Indolent Non-nodal Mantle Cell Lymphoma Revisited.
- Application of thrombolytic drugs on clotted blood and bone marrow specimens to generate usable cells for cytogenetic analyses.
- Clonally related histiocytic/dendritic cell sarcoma and chronic lymphocytic leukemia/small lymphocytic lymphoma: a study of seven cases.
- The B cell antigen receptor in atypical chronic lymphocytic leukemia with t(14;19)(q32;q13) demonstrates remarkable stereotypy.
- Establishment and characterization of a novel Waldenstrom macroglobulinemia cell line, MWCL-1.
- Chronic lymphocytic leukemia with t(14;19)(q32;q13) is characterized by atypical morphologic and immunophenotypic features and distinctive genetic features.
- Isolated del(5q) in myeloid malignancies: clinicopathologic and molecular features in 143 consecutive patients.
- Autologous transplantation gives encouraging results for young adults with favorable-risk acute myeloid leukemia but is not improved with gemtuzumab ozogamicin.
- Reflex fluorescent in situ hybridization testing for unsuccessful product of conception cultures: A retrospective analysis of 5555 samples attempted by conventional cy...
- Successful treatment of a child with T/myeloid acute bilineal leukemia associated with TLX3/BCL11B fusion and 9q deletion.
- C-MYC alterations and association with patient outcome in early-stage HER2-positive breast cancer from the north central cancer treatment group N9831 adjuvant trastuzu...
- Pediatric histiocytic sarcoma clonally related to precursor B-cell acute lymphoblastic leukemia with homozygous deletion of CDKN2A encoding p16INK4A.
- Zosuquidar, a novel modulator of P-glycoprotein, does not improve the outcome of older patients with newly diagnosed acute myeloid leukemia: a randomized, placebo-cont...
- Nearly identical near-haploid karyotype in a peritoneal mesothelioma and a retroperitoneal malignant peripheral nerve sheath tumor.
- HER2 and chromosome 17 effect on patient outcome in the N9831 adjuvant trastuzumab trial.
- Development of a dual-color, double fusion FISH assay to detect RPN1/EVI1 gene fusion associated with inv(3), t(3;3), and ins(3;3) in patients with myelodysplasia and ...
- Development of five dual-color, double-fusion fluorescence in situ hybridization assays for the detection of common MLL translocation partners.
- Evidence for cytogenetic and fluorescence in situ hybridization risk stratification of newly diagnosed multiple myeloma in the era of novel therapie.
- Chromosome 8p11.2 translocations: prevalence, FISH analysis for FGFR1 and MYST3, and clinicopathologic correlates in a consecutive cohort of 13 cases from a single ins...
- Isochromosome 12p and polysomy 12 in primary central nervous system germ cell tumors: frequency and association with clinicopathologic features.
- Comparison of fluorescence in situ hybridization, p57 immunostaining, flow cytometry, and digital image analysis for diagnosing molar and nonmolar products of conception.
- Impact of American Society of Clinical Oncology/College of American Pathologists guideline recommendations on HER2 interpretation in breast cancer.
- T-cell acute lymphoblastic leukemia in adults: clinical features, immunophenotype, cytogenetics, and outcome from the large randomized prospective trial (UKALL XII/ECO...
- Rearrangements and amplification of IER3 (IEX-1) represent a novel and recurrent molecular abnormality in myelodysplastic syndromes.
- CCND1 rearrangements and cyclin D1 overexpression in renal oncocytomas: frequency, clinicopathologic features, and utility in differentiation from chromophobe renal ce...
- Chronic lymphocytic leukemia With t(2;14)(p16;q32) involves the BCL11A and IgH genes and is associated with atypical morphologic features and unmutated IgVH genes.
- Rosette-forming glioneuronal tumor: report of a chiasmal-optic nerve example in neurofibromatosis type 1: special pathology report.
- Translocation t(11;14) and survival of patients with light chain (AL) amyloidosis.
- Trisomy 13: prevalence and clinicopathologic correlates of another potentially lenalidomide-sensitive cytogenetic abnormality.
- Pituitary blastoma.
- A novel report of cig-FISH and cytogenetics in POEMS syndrome.
- Biologic and genetic characterization of the novel amyloidogenic lambda light chain-secreting human cell lines, ALMC-1 and ALMC-2.
- Isolated trisomy 15: a clonal chromosome abnormality in bone marrow with doubtful hematologic significance.
- Evaluation of a commercially available focused aCGH platform for the detection of constitutional chromosome anomalies.
- Comprehensive validation of array comparative genomic hybridization platforms: how much is enough?
- Extending Jak2V617F and MplW515 mutation analysis to single hematopoietic colonies and B and T lymphocytes.
- Clinical correlates of JAK2V617F allele burden in essential thrombocythemia.
- Automated Duet spot counting system and manual technologist scoring using dual-fusion fluorescence in situ hybridization (D-FISH) strategy: comparison and application ...
- Utility of ALK-1 protein expression and ALK rearrangements in distinguishing inflammatory myofibroblastic tumor from malignant spindle cell lesions of the urinary blad...
- Analysis of HER2 gene amplification using an automated fluorescence in situ hybridization signal enumeration system.
- Analysis of genetic abnormalities provides insights into genetic evolution of hyperdiploid myeloma.
- Lenalidomide therapy in myelofibrosis with myeloid metaplasia.
- Splenic small B-cell lymphoma with IGH/BCL3 translocation.
- Preclinical validation of fluorescence in situ hybridization assays for clinical practice.
- Functioning paraganglioma and gastrointestinal stromal tumor of the jejunum in three women: syndrome or coincidence.
- Analysis of intratumoral heterogeneity and amplification status in breast carcinomas with equivocal (2+) HER-2 immunostaining.
- Molecular diagnosis of Ewing's sarcoma/primitive neuroectodermal tumor in formalin-fixed paraffin-embedded tissues by RT-PCR and fluorescence in situ hybridization.
- Leukemic transformation in myelofibrosis with myeloid metaplasia: a single-institution experience with 91 cases.
- FIP1L1-PDGFRA fusion: prevalence and clinicopathologic correlates in 89 consecutive patients with moderate to severe eosinophilia.
- Familial 22q11.2 deletions in DiGeorge/velocardiofacial syndrome are predominantly smaller than the commonly observed 3Mb.
- Histologic and immunohistochemical study of bone marrow monocytic nodules in 21 cases with myelodysplasia.
- CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib mesylate therapy.
- Microduplication 22q11.2, an emerging syndrome: clinical, cytogenetic, and molecular analysis of thirteen patients.
- New highly sensitive fluorescence in situ hybridization method to detect PML/RARA fusion in acute promyelocytic leukemia.
- Utility of subtelomeric fluorescent DNA probes for detection of chromosome anomalies in 425 patients.
- Somatic rearrangement of the TP63 gene preceding development of mycosis fungoides with aggressive clinical course.
- Occurrence and prognostic significance of cytogenetic evolution in patients with multiple myeloma.
- Racial differences in primary cytogenetic abnormalities in multiple myeloma: a multi-center study.
- Novel recurrent mutations in ethanolamine kinase 1 (ETNK1) gene in systemic mastocytosis with eosinophilia and chronic myelomonocytic leukemia.
- Transient monosomy 7 in a chronic myelogenous leukemia patient during nilotinib therapy: a case report.
Schools
Mayo Medical School
Mayo Grad School MedMayo Fndn
Doctors Specialties
- Clinical Cytogenetics
- Pathology
Accepted Insurances
Education
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Mayo School of Graduate Medical Education -
Mayo Medical School
Hospital
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Mayo Clinic - Rochester, Minnesota
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