Physician
Otolaryngology (ENT)
Dr. Richard A. Buckingham, MD
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Richard A. Buckingham practices Otolaryngology (ENT). He researched medicine at University of Illinois College of Medicine. Richard A. Buckingham is a published doctor. He has 79 papers published. The most current publication "A direct estimation of the context effect on the efficiency of termination."
Publications
- No correlation between native and denatured forms of tRNA(Trp) form Escherichia coli and the resistant and sensitive molecules characterised by phosphorolysis. Two cla...
- The effect of an intramolecular cross-link on reversible denaturation in tryptophan transfer ribonucleic acid from Escherichia coli.
- Construction of a UGA suppressor tRNA by modification in vitro of yeast tRNACys.
- Tritium exchange on transfer RNA: slowly exchanging protons sensitive to a change in the dihydrouridine stem.
- An effect of codon context on the mistranslation of UGU codons in vitro.
- Photocrosslinking of thiolated aminoacyl-tRNA to ribosomal RNA and proteins.
- Effect of oligonucleotide AGAGGAGGU on protein synthesis in vitro.
- Characterization of an amber suppressor in Pneumococcus.
- Denaturation of UGA suppressor tRNA-Trp from E. coli.
- Blue dextran Sepharose chromatography of the tryptophanyl-tRNA synthetase of E. coli: a potential application for the purification of the enzyme.
- Does UGA suppressor tRNATrp from Escherichia coli have a unique CCA anticodon sequence?
- Low field nuclear magnetic resonance studies of the structure of UGA suppressor tryptophan tRNA from Escherichia coli; normal and photo-crosslinked species.
- Acylation of Escherichia coli tRNAtrp with 5-methyltryptophan by E. coli tryptophanyl-tRNA ligase.
- Regulation of protein synthesis by minigene expression.
- Anticodon conformation and accessibility in wild-type and suppressor tryptophan tRNA from E. coli.
- The effect of point mutations affecting Escherichia coli tryptophan tRNA on anticodon-anticodon interactions and on UGA suppression.
- Effect of photochemical crosslink S4U(8)-C(13) on suppressor activity of su+ tRNATrp from Escherichia coli.
- The nucleotide sequence of rpsL and its flanking regions in Salmonella typhimurium.
- Codon specificity of UGA suppressor tRNATrp from Escherichia coli.
- Recognition of tRNA Trp by initiation factors from Escherichia coli.
- Does codon composition influence ribosome function?
- Third position base changes in codons 5'' and 3'' adjacent UGA codons affect UGA suppression in vivo.
- Mutants affecting tRNA(Phe) from Escherichia coli. Studies of the suppression of thermosensitive phenylalanyl-tRNA synthetase.
- Codon context.
- Codon context and protein synthesis: enhancements of the genetic code.
- Osmo-expression and fast two-step purification of Escherichia coli translation termination factor RF-3.
- Translational termination comes of age.
- Interaction between dimeric methionyl-tRNA synthetase and methionine accepting tRNAs from E. coli.-- Studies by partial ribonuclease digestion.
- Aminoacylation of tRNA Trp from beef liver, yeast and E. coli by beef pancrease tryptophan-tRNA ligase. Stoichiometry of tRNATrp binding.
- Protection against non-enzymatic deacylation of Met-tRNA Met m by the ribosome : an approach to the measurement of aminoacyl-tRNA : ribosome affinity constants.
- Identification of clones carrying an E. coli tRNAPhe gene by suppression of phenylalanyl-tRNA synthetase thermosensitive mutants.
- Mutant ribosomes can generate dominant kirromycin resistance.
- Missense substitutions lethal to essential functions of EF-Tu.
- Functional mutants of phenylalanine transfer RNA from Escherichia coli.
- Suppression of a double missense mutation by a mutant tRNA(Phe) in Escherichia coli.
- Peptidyl-tRNA hydrolase is involved in lambda inhibition of host protein synthesis.
- A radioactive assay for the physiological activity of the tryptophan synthetase alpha subunit in crude extracts of Escherichia coli.
- Suppression of thermosensitive peptidyl-tRNA hydrolase mutation in Escherichia coli by gene duplication.
- Mutants of pheV in Escherichia coli affecting control by attenuation of the pheS, T and pheA operons. Two distinct mechanisms for de-attenuation.
- Shutdown in protein synthesis due to the expression of mini-genes in bacteria.
- Rapid and precise chromosomal mapping of genomic probes in Escherichia coli using the digital physical map.
- Purification of active Escherichia coli ribosome recycling factor (RRF) from an osmo-regulated expression system.
- Polypeptide chain release factors.
- Sequestration of specific tRNA species cognate to the last sense codon of an overproduced gratuitous protein.
- Bacterial polypeptide release factor RF2 is structurally distinct from eukaryotic eRF1.
- A posttermination ribosomal complex is the guanine nucleotide exchange factor for peptide release factor RF3.
- Cleavage of colicin D is necessary for cell killing and requires the inner membrane peptidase LepB.
- Origins of minigene-dependent growth inhibition in bacterial cells.
- The accuracy of codon recognition by polypeptide release factors.
- Localization and characterization of the gene encoding release factor RF3 in Escherichia coli.
- A direct estimation of the context effect on the efficiency of termination.
- Initiation factors IF1 and IF2 synergistically remove peptidyl-tRNAs with short polypeptides from the P-site of translating Escherichia coli ribosomes.
- Ribosome release factor RF4 and termination factor RF3 are involved in dissociation of peptidyl-tRNA from the ribosome.
- Release factor RF3 abolishes competition between release factor RF1 and ribosome recycling factor (RRF) for a ribosome binding site.
- Fast recycling of Escherichia coli ribosomes requires both ribosome recycling factor (RRF) and release factor RF3.
- A post-translational modification in the GGQ motif of RF2 from Escherichia coli stimulates termination of translation.
- Novel roles for classical factors at the interface between translation termination and initiation.
- Release factor RF3 in E.coli accelerates the dissociation of release factors RF1 and RF2 from the ribosome in a GTP-dependent manner.
- The growth defect in Escherichia coli deficient in peptidyl-tRNA hydrolase is due to starvation for Lys-tRNA(Lys).
- Function of polypeptide chain release factor RF-3 in Escherichia coli. RF-3 action in termination is predominantly at UGA-containing stop signals.
- Mechanism of activation of methyltransferases involved in translation by the Trm112 ''hub'' protein.
- Novel Escherichia coli RF1 mutants with decreased translation termination activity and increased sensitivity to the cytotoxic effect of the bacterial toxins Kid and RelE.
- HemK2 protein, encoded on human chromosome 21, methylates translation termination factor eRF1.
- Dual roles of the central domain of colicin D tRNase in TonB-mediated import and in immunity.
- Methylation of bacterial release factors RF1 and RF2 is required for normal translation termination in vivo.
- The zinc finger protein Ynr046w is plurifunctional and a component of the eRF1 methyltransferase in yeast.
- The SAXS solution structure of RF1 differs from its crystal structure and is similar to its ribosome bound cryo-EM structure.
- Molecular basis for bacterial class I release factor methylation by PrmC.
- Import of the transfer RNase colicin D requires site-specific interaction with the energy-transducing protein TonB.
- The N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase PrmC/HemK in Chlamydia trachomatis methylates class 1 release factors.
- The glutamine residue of the conserved GGQ motif in Saccharomyces cerevisiae release factor eRF1 is methylated by the product of the YDR140w gene.
- Structural inhibition of the colicin D tRNase by the tRNA-mimicking immunity protein.
- Stop codon recognition and interactions with peptide release factor RF3 of truncated and chimeric RF1 and RF2 from Escherichia coli.
- The essential role of the invariant GGQ motif in the function and stability in vivo of bacterial release factors RF1 and RF2.
- Importation of nuclease colicins into E coli cells: endoproteolytic cleavage and its prevention by the immunity protein.
- Release of peptide promoted by the GGQ motif of class 1 release factors regulates the GTPase activity of RF3.
- Peptidyl-tRNA hydrolase in Bacillus subtilis, encoded by spoVC, is essential to vegetative growth, whereas the homologous enzyme in Saccharomyces cerevisiae is dispens...
- The hemK gene in Escherichia coli encodes the N(5)-glutamine methyltransferase that modifies peptide release factors.
Schools
University of Illinois At Chicago College of Medicine
Cook Co Hospital
Doctors Specialties
- Ear, Nose, and Throat
- Otolaryngology (ENT)
Accepted Insurances
Education
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John H. Stroger Hospital of Cook County -
University of Illinois College of Medicine
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