Professor, Radiology, Georgetown University School of Medicine
Radiology
Dr. Richard C. Reba, MD
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Richard Reba is an expert in the field of Radiology. Richard Reba is also published. He has 101 publications published. The lastest publication: "In vivo competition studies of Z-(-,-)-125IIQNP against 3-quinuclidinyl 2-(5-bromothienyl)-2-thienylglycolate (BrQNT) demonstrating in vivo m2 muscarinic subtype selec...'
Publications
- Modeling [(18)F]-FDG lymphoid tissue kinetics to characterize nonhuman primate immune response to Middle East respiratory syndrome-coronavirus aerosol challenge.
- Whole-body imaging of the immune system reveals discordance in CD4+ lymphoid tissue recovery after transplantation in rhesus macaques.
- Progress using Tc-99m radiopharmaceuticals for measuring high capacity sites and low density sites.
- Evaluation of monkeypox disease progression by molecular imaging.
- Gamma probes and their use in tumor detection in colorectal cancer.
- Targeted imaging: an important biomarker for understanding disease progression in the era of personalized medicine.
- Positron emission tomography in the diagnosis and management of giant cell arteritis.
- Hypoxia: importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy.
- Incorporation of SPECT bone marrow imaging into intensity modulated whole-pelvic radiation therapy treatment planning for gynecologic malignancies.
- A Korean kindred with autosomal dominant nocturnal frontal lobe epilepsy and mental retardation.
- Binary methods for the microdosimetric analysis of cell survival data from alpha-particle irradiation.
- Characterization of an alpha-particle irradiator for individual cell dosimetry measurements.
- Image processing tools for alpha-particle track-etch dosimetry.
- Imaging of ischemic heart disease.
- In vitro and in vivo m2 muscarinic subtype selectivity of some dibenzodiazepinones and pyridobenzodiazepinones.
- Diagnostic imaging and the outcome of acute lower gastrointestinal bleeding.
- In vivo competition studies of Z-(-,-)-125IIQNP against 3-quinuclidinyl 2-(5-bromothienyl)-2-thienylglycolate (BrQNT) demonstrating in vivo m2 muscarinic subtype selec...
- Nuclear medicine physician workforce requirements, Part 2: Benchmarking U.S. nuclear medicine physician workforce requirements based on managed care organization effec...
- Scintigraphic screening prior to visceral arteriography in acute lower gastrointestinal bleeding.
- In vitro and in vivo studies on the development of the alpha-emitting radionuclide bismuth 212 for intraperitoneal use against microscopic ovarian carcinoma.
- Correction of the stereochemical assignment of the benzilic acid center in (R)-(-)-3-quinuclidinyl (S)-(+)-4-iodobenzilate (R,S)-4-IQNB.
- Molecular modeling of the interaction of diagnostic radiopharmaceuticals with receptor proteins: m2 antagonist binding to the muscarinic m2 subtype receptor.
- In vivo autoradiography of radioiodinated (R)-3-quinuclidinyl (S)-4-iodobenzilate (R, S)-IQNB and (R)-3-quinuclidinyl (R)-4-iodobenzilate (R,R)-IQNB. Comparison of the...
- Future nuclear medicine physician requirements.
- Evaluation of 1-azabicyclo2.2.2oct-3-yl alpha-fluoroalkyl-alpha-hydroxy-alpha-phenylacetates as potential ligands for the study of muscarinic receptor density by posit...
- Specific binding component of the "inactive" stereoisomer (S,S)-125I IQNB to rat brain muscarinic receptors in vivo.
- Comparison of technetium-99m sestamibi-gated tomographic perfusion imaging with echocardiography and electrocardiography for determination of left ventricular mass.
- Autoradiographic evidence that 3-quinuclidinyl-4-fluorobenzilate (FQNB) displays in vivo selectivity for the m2 subtype.
- Resolution and in vitro and initial in vivo evaluation of isomers of iodine-125-labeled 1-azabicyclo2.2.2oct-3-yl alpha-hydroxy-alpha-(1-iodo-1-propen-3-yl)-alpha-phen...
- Autoradiographic evidence that quinuclidinyl 4-(bromophenyl)-2-thienylglycolate (QBPTG) displays in vivo selectivity for the muscarinic m2 subtype.
- Tumor receptor imaging: proceedings of the National Cancer Institute workshop, review of current work, and prospective for further investigations.
- Characterization of in vivo brain muscarinic acetylcholine receptor subtype selectivity by competition studies against (R,S)-125IIQNB.
- Autoradiographic evidence that QNB displays in vivo selectivity for the m2 subtype.
- Comparison of the in vivo rat brain regional pharmacokinetics of 3HQNB, (R,S)-125I-4IQNB, and (R,R)-125I-4IQNB binding to the muscarinic acetylcholine receptor in rela...
- Kinetic analysis of rat exocrine gland muscarinic receptors in vivo.
- Lines from the president.
- 3-alpha-Chlorimperialine: an M2-selective muscarinic receptor antagonist that penetrates into brain.
- Muscarinic receptor selectivities of 3-Quinuclidinyl 8-xanthenecarboxylate (QNX) in rat brain.
- 3HQNB displays in vivo selectivity for the m2 subtype.
- A malignant melanoma imaging agent: synthesis, characterization, in vitro binding and biodistribution of iodine-125-(2-piperidinylaminoethyl)4-iodobenzamide.
- PET and SPECT: opportunities and challenges for psychiatry.
- Nuclear medicine.
- Evaluation of reconstruction algorithms in SPECT neuroimaging: II. Computation of deterministic and statistical error components.
- Evaluation of reconstruction algorithms in SPECT neuroimaging: I. Comparison of statistical noise in SPECT neuroimages with ''naive'' and ''realistic'' predictions.
- Kinetic analysis of rat parotid gland muscarinic receptors in vivo: comparison with brain and heart.
- Synthesis and structure-activity relationship of some 5-(dialkylamino)alkyl-1-piperidinylacetyl-10,11-dihydro-5H- benzob,e1,4diazepin-11-ones as M2-selective antimusca...
- Estimation of relative regional neuroreceptor concentration by PET or SPECT: Theoretical comparisons of using a single late image or a late plus early image.
- An improved synthesis of 125IN-(diethylaminoethyl)-4-iodobenzamide: a potential ligand for imaging malignant melanoma.
- A novel muscarinic receptor ligand which penetrates the blood brain barrier and displays in vivo selectivity for the m2 subtype.
- Two antigens detected on human ocular melanomas with the mouse monoclonal antibodies 2/10SN and 10/12SN.
- Radiolabeled products in rat liver and serum after administration of antibody-amide-DTPA-indium-111.
- Use of ex vivo binding to measure the brain concentrations of putative radioligands.
- A novel m2-selective muscarinic antagonist: binding characteristics and autoradiographic distribution in rat brain.
- Compensation for three-dimensional detector response, attenuation and scatter in SPECT grey matter imaging using an iterative reconstruction algorithm which incorporat...
- Synthesis and receptor affinities of new 3-quinuclidinyl alpha-heteroaryl-alpha-aryl-alpha-hydroxyacetates.
- Synthesis, characterization and biodistribution of a new hexadentate aminethiol ligand labeled with Tc-99m.
- In vivo imaging of cerebral muscarinic receptors with I-123 QNB and SPECT: studies in normal subjects and patients with dementia.
- 3-D SPECT simulations of a complex 3-D mathematical brain model: effects of 3-D geometric detector response, attenuation, scatter, and statistical noise.
- Pharmacokinetic simulations of SPECT quantitation of the M2 muscarinic neuroreceptor subtype in disease states using radioiodinated (R,R)-4IQNB.
- The in vitro dissociation kinetics of (R,R)-[125I]4IQNB is reflected in the in vivo washout of the radioligand from rat brain.
- A comparison of FDG PET and IQNB SPECT in normal subjects and in patients with dementia.
- Synthesis and muscarinic cholinergic receptor affinities of 3-quinuclidinyl alpha-(alkoxyalkyl)-alpha-aryl-alpha-hydroxyacetates.
- Three-dimensional SPECT simulations of a complex three-dimensional mathematical brain model and measurements of the three-dimensional physical brain phantom.
- Binding of radioiodinated SPECT ligands to transfected cell membranes expressing single muscarinic receptor subtypes.
- Urinary fibrinopeptide A in evaluation of patients with suspected acute pulmonary embolism. A prospective pilot study.
- In vivo dissociation kinetics of 3Hquinuclidinyl benzilate: relationship to muscarinic receptor concentration and in vitro kinetics.
- The distribution of cerebral muscarinic acetylcholine receptors in vivo in patients with dementia. A controlled study with 123IQNB and single photon emission computed ...
- Three-dimensional simulations of multidetector point-focusing SPECT imaging.
- 3-D computer simulations of resolution effects of multidetector point focusing SPECT imaging.
- Muscarinic receptor subtype selectivity of novel heterocyclic QNB analogues.
- Kinetic analysis of 3-quinuclidinyl 4-125Iiodobenzilate transport and specific binding to muscarinic acetylcholine receptor in rat brain in vivo: implications for huma...
- Specific in vivo binding of 125I-iodomelatonin to melatonin receptors in rat brain.
- Immunoreactivity affects the biodistribution and tumor targeting of radiolabeled anti-P97 Fab fragment.
- Single photon emission computed tomography in phencyclidine and related drug abuse.
- Theoretical investigation of the estimation of relative regional neuroreceptor concentration from a single SPECT or PET image.
- Quantification of the dopamine D2 receptor in the living human caudate nucleus by PET: comparison of in vivo and in vitro kinetic parameters.
- Optimization of biodistribution by introducing different chemical linkages between antibody and an indium-111 chelate.
- Cerebral muscarinic receptors in primary degenerative dementia as evaluated by SPECT with iodine-123-labeled QNB.
- The use of indium-111 labeled platelet scanning for the detection of asymptomatic deep venous thrombosis in a high risk population.
- Reduction of background activities by introduction of a diester linkage between antibody and a chelate in radioimmunodetection of tumor.
- Preparation and properties of (R)-(-)-1-azabicyclo2.2.2oct-3-yl- (R)-(+)-alpha-hydroxy-alpha-(4-125Iiodophenyl)-alpha-phenyl acetate and (R)-(-)-1-azabicyclo2.2.2oct-3...
- In vitro and in vivo characteristics of [iodine-125] 3-(R)-quinuclidinyl (S)-4-iodobenzilate.
- Platelet survival and turnover: important factors in predicting response to splenectomy in immune thrombocytopenic purpura.
- Clinical and hemodynamic significance of left ventricular diastolic volume changes by exercise radionuclide ventriculography in coronary artery disease.
- Interposition of different chemical linkages between antibody and 111In-DTPA to accelerate clearance from non-target organs and blood.
- Gallbladder visualization during technetium-99m RBC blood pool imaging. Case report and literature review.
- Elevated D2 dopamine receptors in drug-naïve schizophrenics.
- Accuracy of in vivo neuroreceptor quantification by PET and review of steady-state, transient, double injection, and equilibrium models.
- Theoretical effects of radioligand diffusional gradients and microscopic neuroreceptor distribution in in vivo kinetic studies.
- Synthesis and structure-activity relationships of new muscarinic antagonists.
- 125I17-alpha-iodovinyl 11-beta-methoxyestradiol interaction in vivo with estrogen receptors in hormone-independent MCF-7 human breast cancer transfected with the v-ras...
- Binding characteristics and biological activity of 17 alpha-125Iiodovinyl-11 beta-methoxyestradiol, an estrogen receptor-binding radiopharmaceutical, in human breast c...
- Transchelation of 99mTc from low affinity sites to high affinity sites of antibody.
- Muscarinic acetylcholine receptors in Alzheimer''s disease. In vivo imaging with iodine 123-labeled 3-quinuclidinyl-4-iodobenzilate and emission tomography.
- Use of 3-quinuclidinyl 4-iodobenzilate as a receptor binding radiotracer.
- Relative reactivity of DTPA, immunoreactive antibody-DTPA conjugates, and nonimmunoreactive antibody-DTPA conjugates toward indium-111.
- The labeling of high affinity sites of antibodies with 99mTc.
- Receptor-selective localization in pancreas.
- Exercise radionuclide ventriculographic responses in hypertensive patients with chest pain.
- Synthesis and evaluation of (17 alpha,20E)-21-125Iiodo-19-norpregna-1,3,5(10),20-tetraene-3,17 -diol and (17 alpha,20E)-21-125Iiodo-11 beta-methoxy-19-norpregna-1,3,5(...
Schools
University of Maryland At Baltimore Professional Schools
Tripler Army Med Center
University MD Hospital
Johns Hopkins Hospital
Doctors Specialties
- Internal Medicine
- Nuclear Medicine
- Radiology
Accepted Insurances
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