Professor, Medicine, Case Western Reserve University School of Medicine
Infectious Disease
Dr. Robert A. Bonomo, MD
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Robert A. Bonomo, MD works in the field of Infectious Disease. He graduated from Case Western Reserve University School of Medicine. Robert Bonomo is a published doctor and has 99 publications published. The lastest was: 'Ertapenem for the treatment of bloodstream infections due to ESBL-producing Enterobacteriaceae: a multinational pre-registered cohort study.'
Publications
- Hospital Readmissions in Patients With Carbapenem-Resistant Klebsiella pneumoniae.
- Ertapenem for the treatment of bloodstream infections due to ESBL-producing Enterobacteriaceae: a multinational pre-registered cohort study.
- Spectrum of excess mortality due to carbapenem-resistant Klebsiella pneumoniae infections.
- The Prevalence and Molecular Epidemiology of Multidrug-Resistant Enterobacteriaceae Colonization in a Pediatric Intensive Care Unit.
- Trousseau's Syndrome in Cholangiocarcinoma: the Risk of Making the Diagnosis.
- Intestinal Carriage of Carbapenemase-Producing Organisms: Current Status of Surveillance Methods.
- The Complex Epidemiology of Carbapenem-Resistant Enterobacter Infections: A Multicenter Descriptive Analysis.
- FOX-4 cephamycinase: an analysis of structure and function.
- SHV-129: A Gateway to Global Suppressors in the SHV β-Lactamase Family?
- Are Staphylococcus intermedius Infections in Humans Cases of Mistaken Identity? A Case Series and Literature Review.
- Fulminant endocarditis and disseminated infection caused by carbapenem-resistant Acinetobacter baumannii in a renal-pancreas transplant recipient.
- SISPA-Seq for rapid whole genome surveys of bacterial isolates.
- Structural Basis of Activity against Aztreonam and Extended Spectrum Cephalosporins for Two Carbapenem-Hydrolyzing Class D β-Lactamases from Acinetobacter baumannii.
- Complete sequence of a blaKPC-harboring co-integrate plasmid isolated from Escherichia coli.
- Variants of the KPC-2 β-lactamase which are resistant to inhibition by avibactam.
- Avibactam and inhibitor resistant SHV β-lactamases.
- Detecting a quasi-stable imine species on the reaction pathway of SHV-1 β-lactamase and 6β-(hydroxymethyl)penicillanic acid sulfone.
- Bloodstream Infection Caused by Extended-Spectrum β-Lactamase-Producing Gram-Negative Bacteria: How to Define the Best Treatment Regimen?
- Unexpected Challenges in Treating Multidrug-resistant Gram-negative Rods: Resistance to Ceftazidime-Avibactam in Archived Isolates of Pseudomonas aeruginosa.
- Salvage microbiology: opportunities and challenges in the detection of bacterial pathogens following initiation of antimicrobial treatment.
- Impact of therapy and strain type on outcomes in urinary tract infections caused by carbapenem-resistant Klebsiella pneumoniae.
- Host Fate Is Rapidly Determined by Innate Effector-Microbial Interactions During Acinetobacter baumannii Bacteremia.
- Biochemical and Structural Analysis of Inhibitors Targeting the ADC-7 Cephalosporinase of Acinetobacter baumannii.
- Biochemical, Mechanistic, and Spectroscopic Characterization of Metallo-β-lactamase VIM-2.
- Antibiotic-resistant gram-negative bacterial infections in patients with cancer.
- Epithelial innate immune response to Acinetobacter baumannii challenge.
- Genomic and transcriptomic analyses of colistin-resistant clinical isolates of Klebsiella pneumoniae reveal multiple pathways of resistance.
- Carbapenemase-producing Klebsiella pneumoniae: molecular and genetic decoding.
- Extensively Drug-Resistant Pseudomonas aeruginosa Isolates Containing blaVIM-2 and Elements of Salmonella Genomic Island 2: a New Genetic Resistance Determinant in Nor...
- Understanding the determinants of substrate specificity in IMP family metallo-β-lactamases: The importance of residue 262.
- Acute respiratory distress caused by Neosartorya udagawae.
- A fluorescent carbapenem for structure function studies of penicillin-binding proteins, β-lactamases, and β-lactam sensors.
- Erratum for Wright et al., Population Structure of KPC-Producing Klebsiella pneumoniae Isolates from Midwestern U.S. Hospitals.
- Following Drug Uptake and Reactions inside Escherichia coli Cells by Raman Microspectroscopy.
- Tigecycline Therapy for Carbapenem-Resistant Klebsiella pneumoniae (CRKP) Bacteriuria Leads to Tigecycline Resistance.
- Infections caused by fluoroquinolone-resistant Escherichia coli following transrectal ultrasound-guided biopsy of the prostate.
- Identification of Occult Fusobacterium nucleatum Central Nervous System Infection Using PCR Electrospray Ionization Mass Spectrometry (PCR/ESI-MS).
- Population Structure of KPC-producing Klebsiella pneumoniae from Midwestern US hospitals.
- Direct Detection of Indirect Transmission of Streptobacillus moniliformis Rat Bite Fever Infection.
- The Deadly Impact of Extreme Drug Resistance in Acinetobacter baumannii*.
- Complex prosthetic joint infections due to carbapenemase-producing Klebsiella pneumoniae: a unique challenge in the era of untreatable infections.
- Multi-Drug-Resistant Klebsiella pneumoniae Pancreatitis: A New Challenge in a Serious Surgical Infection.
- Vaccines for Acinetobacter baumannii: Thinking "out of the box".
- Reclaiming the efficacy of β-lactam-β-lactamase inhibitor combinations: avibactam restores the susceptibility of ceftazidime against CMY-2-producing Escherichia coli.
- Surveillance of Carbapenem-Resistant Klebsiella pneumoniae: Tracking Molecular Epidemiology and Outcomes through a Regional Network.
- Multiplex PCR for identification of two capsular types in epidemic KPC-producing Klebsiella pneumoniae ST258 strains.
- Molecular dissection of the evolution of carbapenem-resistant multilocus sequence type 258 Klebsiella pneumoniae.
- Ureaplasma parvum Prosthetic Joint Infection Detected by PCR.
- Antibacterial Resistance Leadership Group: Open for Business.
- "An epidemic plasmid in an endemic region": comparative genomic analysis of KPC-encoding pKpQIL-like plasmids and their distribution in New Jersey and New York hospitals.
- A molecular survey of the dissemination of two blaKPC-harboring IncFIA plasmids in New Jersey and New York hospitals.
- Pseudo-outbreak of Klebsiella oxytoca spontaneous bacterial peritonitis attributed to contamination of multidose vials of culture medium supplement.
- Penam Sulfones and β-Lactamase Inhibition: SA2-13 and the Importance of the C2 Side Chain Length and Composition.
- Complete sequence of a KPC-producing IncN multidrug-resistant plasmid from an epidemic Escherichia coli ST131 strain in China.
- Structural Origins of Oxacillinase Specificity in Class D β-Lactamases.
- Better tests, better care: improved diagnostics for infectious diseases.
- New β-lactamase inhibitors: A therapeutic renaissance in an "MDR world"!
- β-Lactamase Inhibition by 7-Alkylidenecephalosporin Sulfones: Allylic Transposition and Formation of an Unprecedented Stabilized Acyl-Enzyme.
- A kinetic analysis of the inhibition of FOX-4 β-lactamase, a plasmid-mediated AmpC cephalosporinase, by monocyclic β-lactams and carbapenems.
- OqxAB, a Quinolone and Olaquindox Efflux Pump, Is Widely Distributed among Multidrug-Resistant Klebsiella pneumoniae Isolates of Human Origin.
- Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases.
- Can inhibitor resistant substitutions in the Mycobacterium tuberculosis β-lactamase BlaC lead to clavulanate resistance? A biochemical rationale for the use of β-lacta...
- "Airborne Assault": A New Dimension in Acinetobacter baumannii Transmission*.
- STRUCTURES OF THE CLASS D CARBAPENEMASES OXA-23 AND OXA-146: MECHANISTIC BASIS OF ACTIVITY AGAINST CARBAPENEMS, EXTENDED-SPECTRUM CEPHALOSPORINS AND AZTREONAM.
- PCR and Electrospray Ionization Mass Spectrometry (PCR/ESI-MS): Detection of Persistent Enterococcus faecalis in Cerebrospinal Fluid following Treatment of Post-Operat...
- Complete nucleotide sequence of a blaKPC-harboring IncI2 plasmid and its dissemination in New Jersey and New York hospitals: a hidden threat.
- Class D β-Lactamases: A Reappraisal after Five Decades.
- Insights into β-lactamases from Burkholderia species, two phylogenetically related yet distinct resistance determinants.
- 10 x '20 Progress--Development of New Drugs Active Against Gram-Negative Bacilli: An Update From the Infectious Diseases Society of America.
- Specialty Care Delivery: Bringing Infectious Disease Expertise to the Residents of a Veterans Affairs Long-Term Care Facility.
- "Stormy waters ahead": global emergence of carbapenemases.
- Complete Sequence of a blaKPC-2-Harboring IncFIIK1 Plasmid from a Klebsiella pneumoniae Sequence Type 258 Strain.
- Raman Spectra of Interchanging ?-Lactamase Inhibitor Intermediates on the Millisecond Time Scale.
- Design and Exploration of Novel Boronic Acid Inhibitors Reveals Important Interactions with a Clavulanic Acid-Resistant Sulfhydryl-Variable (SHV) ?-Lactamase.
- Carbapenem-resistant Enterobacteriaceae: a review of treatment and outcomes.
- Acinetobacter baumannii rOmpA vaccine dose alters immune polarization and immunodominant epitopes.
- Complete nucleotide sequence of blaKPC-4 and blaKPC-5 harboring IncN and IncX plasmids from Klebsiella pneumoniae strains isolated in New Jersey.
- Effective Antimicrobial Stewardship in a Long-Term Care Facility through an Infectious Disease Consultation Service: Keeping a LID on Antibiotic Use.
- Structures of SHV-1 β-Lactamase with Penem and Penam Sulfone Inhibitors That Form Cyclic Intermediates Stabilized by Carbonyl Conjugation.
- Early insights into the interactions of different β-lactam antibiotics and β-lactamase inhibitors against soluble forms of Acinetobacter baumannii PBP1a and Acinetob...
- Carboxylation and Decarboxylation of Active Site Lys 84 Controls the Activity of OXA-24 β-Lactamase of Acinetobacter baumannii : Raman Crystallographic and Solution Ev...
- Understanding the molecular determinants of substrate and inhibitor specificity in the carbapenemase, KPC-2: exploring the roles of Arg220 and Glu276.
- The importance of the trans-enamine intermediate as a β-lactamase inhibition strategy probed in inhibitor-resistant SHV β-lactamase variants.
- Active and Passive Immunization Protects against Lethal, Extreme Drug Resistant-Acinetobacter baumannii Infection.
- Partial Excision of blaKPC from Tn4401 in Carbapenem-Resistant Klebsiella pneumoniae.
- In Vitro Activity of Antibiotic Combinations against Multidrug Resistant Strains of Acinetobacter baumannii and the Effects of their Antibiotic Resistance Determinants.
- Inactivation of a class A and a class C β-lactamase by 6β-(hydroxymethyl)penicillanic acid sulfone.
- Can We Really Use ss-Lactam/ss-Lactam Inhibitor Combinations for the Treatment of Infections Caused by Extended-Spectrum ss-Lactamase-Producing Bacteria?
- Resistance Emergence Mechanism and Mechanism of Resistance Suppression by Tobramycin for Cefepime for Pseudomonas aeruginosa.
- Interlaboratory reproducibility of DiversiLab rep-PCR typing and clustering of Acinetobacter baumannii isolates.
- Outcomes and genetic relatedness of carbapenem-resistant enterobacteriaceae at detroit medical center.
- Carbapenems: past, present, and future.
- Longitudinal epidemiology of multidrug-resistant (MDR) Acinetobacter species in a tertiary care hospital.
- Extended-Spectrum AmpC in Acinetobacter baumannii; ADC-56 Confers Resistance to Cefepime.
- Multicenter Evaluation of a New DNA Microarray for the Rapid Detection of Clinically Relevant bla Genes from {beta}-Lactam Resistant Gram-Negative Bacteria.
- Acinetobacter baumannii isolates from pets and horses in Switzerland: molecular characterization and clinical data.
- Analysis of surface motility in Acinetobacter baumannii.
- Increasing prevalence and dissemination of NDM-1 metallo-β-lactamase in India: data from the SMART study (2009).
Schools
Case Western Reserve University School of Medicine
University Hosps
Doctors Specialties
- Geriatric Medicine
- Infectious Disease Medicine
- Infectious Disease
Accepted Insurances
- Medicare MCR
- Tricare
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
Education
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Case Western Reserve University - University Hospitals -
Case Western Reserve University School of Medicine
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