Chief, Perinatology Research Branch; Head, Program for Perinatal Research and Obstetrics; NICHD, NIH

Obstetrics & Gynecology

Roberto Romero is an expert in the field of Obstetrics & Gynecology. He received awards:"Elected Member" and "Fellow (FACOG)". Dr. Roberto J. Romero is a published physician. He published 94 publications, including: 'Invariant NKT Cell Activation Induces Late Preterm Birth That Is Attenuated by Rosiglitazone.'

Publications

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• Vaginal progesterone to prevent preterm birth in pregnant women with a sonographic short cervix: clinical and public health implications.
• Invariant NKT Cell Activation Induces Late Preterm Birth That Is Attenuated by Rosiglitazone.
• The frequency of acute atherosis in normal pregnancy and preterm labor, preeclampsia, small-for-gestational age, fetal death and midtrimester spontaneous abortion.
• Intelligent navigation to improve obstetrical sonography.
• Meconium Aspiration Syndrome: A Role for Fetal Systemic Inflammation.
• Prospective Evaluation of the Fetal Heart Using Fetal Intelligent Navigation Echocardiography (FINE): Evaluation of the Fetal Heart using FINE.
• Vaginal progesterone, but not 17α-hydroxyprogesterone caproate, has anti-inflammatory effects at the murine maternal-fetal interface.
• Evidence of Perturbations of the Cytokine Network in Preterm Labor.
• Reduced expression of the epidermal growth factor signaling system in preeclampsia.
• Umbilical cord prostaglandins in term and preterm parturition.
• A rapid interleukin-6 bedside test for the identification of intra-amniotic inflammation in preterm labor with intact membranes.
• A point of care test for interleukin-6 in amniotic fluid in preterm prelabor rupture of membranes: a step toward the early treatment of acute intra-amniotic inflammati...
• Predicting protein phosphorylation from gene expression: top methods from the IMPROVER Species Translation Challenge.
• Inter-species pathway perturbation prediction via data-driven detection of functional homology.
• Identification of a gene in Mycoplasma hominis associated with preterm birth and microbial burden in intraamniotic infection.
• [54-OR]: When is maternal plasma sST2 concentration elevated in patients with preeclampsia?
• [80-OR]: Increased protein network connectivity in preeclampsia.
• [90-OR]: Novel biomarkers for early preeclampsia derived from the use of a new proteomic method.
• Prediction of preterm birth in twin gestations using biophysical and biochemical tests.
• Personalized third-trimester fetal growth evaluation: comparisons of individualized growth assessment, percentile line and conditional probability methods.
• Prevalence and clinical significance of sterile intra-amniotic inflammation in patients with preterm labor and intact membranes.
• Is 17α-hydroxyprogesterone caproate contraindicated in twin gestations?
• Maternal plasma fetuin-A concentration is lower in patients who subsequently developed preterm preeclampsia than in uncomplicated pregnancy: a longitudinal study.
• Age-related increases in long-range connectivity in fetal functional neural connectivity networks in utero.
• Sterile intra-amniotic inflammation in asymptomatic patients with a sonographic short cervix: prevalence and clinical significance.
• A point of care test for the determination of amniotic fluid interleukin-6 and the chemokine CXCL-10/IP-10.
• Sterile and Microbial-associated Intra-amniotic Inflammation in Preterm Prelabor Rupture of Membranes.
• Endocan, A Putative Endothelial Cell Marker, is Elevated in Preeclampsia, Decreased in Acute Pyelonephritis, and Unchanged in Other Obstetrical Syndromes.
• Fetal growth cessation in late pregnancy: its impact on predicted size parameters used to classify small for gestational age neonates.
• A modified prenatal growth assessment score for the evaluation of fetal growth in the third trimester using single and composite biometric parameters.
• Pre-eclampsia part 2: prediction, prevention and management.
• Pre-eclampsia part 1: current understanding of its pathophysiology.
• Apoptosis of Alcohol-Exposed Human Placental Cytotrophoblast Cells is Downstream of Intracellular Calcium Signaling.
• Progesterone to prevent spontaneous preterm birth.
• Evaluation of Utero-placental and Fetal Hemodynamic Parameters Throughout Gestation in Pregnant Mice Using High-Frequency Ultrasound.
• A Novel Molecular Microbiologic Technique for the Rapid Diagnosis of Microbial Invasion of the Amniotic Cavity and Intra-Amniotic Infection in Preterm Labor with Intac...
• In appreciation of the leadership and stewardship of Drs Thomas J. Garite and Moon H. Kim.
• Biodistribution of Fluorescently Labeled PAMAM Dendrimers in Neonatal Rabbits: Effect of Neuroinflammation.
• MR venography of the fetal brain using susceptibility weighted imaging.
• Transcriptome interrogation of human myometrium identifies differentially expressed sense-antisense pairs of protein-coding and long non-coding RNA genes in spontaneou...
• Analysis and correction of crosstalk effects in pathway analysis.
• Individualized fetal growth assessment: critical evaluation of key concepts in the specification of third trimester size trajectories.
• Fetal production of growth factors and inflammatory mediators predicts pulmonary hypertension in congenital diaphragmatic hernia.
• Concurrent Quantification of Tryptophan and Its Major Metabolites.
• The diagnostic performance of the Mass Restricted (MR) score in the identification of microbial invasion of the amniotic cavity or intra-amniotic inflammation is not s...
• Bacteria and Endotoxin in Meconium-Stained Amniotic Fluid at Term: Could Intra-amniotic Infection Cause Meconium Passage?
• Fetal Intelligent Navigation Echocardiography (FINE): a novel method for rapid, simple, and automatic examination of the fetal heart.
• Mirror Artifacts in Obstetric Ultrasound: Case Presentation of a Ghost Twin during the Second-Trimester Ultrasound Scan.
• Secreted Phospholipase A2 is Increased in Meconium-Stained Amniotic Fluid of Term Gestations: Potential Implications for the Genesis of Meconium Aspiration Syndrome.
• The anti-aging factor α-klotho during human pregnancy and its expression in pregnancies complicated by small-for-gestational-age neonates and/or preeclampsia.
• Detection of Anti-HLA Antibodies in Maternal Blood in the Second Trimester to Identify Patients at Risk of Antibody-Mediated Maternal Anti-Fetal Rejection and Spontane...
• Maternal Floor Infarction/Massive Perivillous Fibrin Deposition: A Manifestation of Maternal Antifetal Rejection?
• Strengths and limitations of microarray-based phenotype prediction: Lessons learned from the IMPROVER Diagnostic Signature Challenge.
• A Novel ERAP2 Haplotype Structure in a Chilean Population: Implications for ERAP2 Protein Expression and Preeclampsia Risk.
• Transdermal nitroglycerin for the treatment of preterm labor: a systematic review and metaanalysis.
• Characterization of the Fetal Blood Transcriptome and Proteome in Maternal Anti-Fetal Rejection: Evidence of a Distinct and Novel Type of Human Fetal Systemic Inflamma...
• Prolactin Receptor Gene Polymorphisms Are Associated with Gestational Diabetes.
• Soluble ST2, a Modulator of the Inflammatory Response, in Preterm and Term Labor.
• Maternal Plasma Soluble TRAIL is Decreased in Preeclampsia.
• Plasma Concentrations of Angiogenic/Anti-Angiogenic Factors Have Prognostic Value in Women Presenting With Suspected Preeclampsia to the Obstetrical Triage Area: A Pro...
• "Trophoblast islands of the chorionic connective tissue" (TICCT): a novel placental histologic feature.
• Soluble ST2 in the Fetal Inflammatory Response Syndrome: In-vivo Evidence of Activation of the Anti-inflammatory Limb of the Immune Response.
• Maternal Plasma Concentrations of sST2 and Angiogenic/Anti-angiogenic Factors in Preeclampsia.
• Soluble TRAIL in Normal Pregnancy and Acute Pyelonephritis: a Potential Explanation for the Susceptibility of Pregnant Women to Microbial Products and Infection.
• The maternal HLA-G 1597?C null mutation is associated with increased risk of pre-eclampsia and reduced HLA-G expression during pregnancy in African-American women.
• Cross-hemispheric functional connectivity in the human fetal brain.
• Endoglin in amniotic fluid as a risk factor for the subsequent development of bronchopulmonary dysplasia.
• Magnetic resonance diffusion-weighted imaging: reproducibility of regional apparent diffusion coefficients for the normal fetal brain.
• Prospective validation of fetal weight estimation using fractional limb volume.
• Evidence of an imbalance of angiogenic/antiangiogenic factors in massive perivillous fibrin deposition (maternal floor infarction): a placental lesion associated with ...
• Maternal plasma concentrations of angiogenic/antiangiogenic factors in the third trimester of pregnancy to identify the patient at risk for stillbirth at or near term ...
• Comparison of the mechanisms responsible for cervical remodeling in preterm and term labor.
• Progesterone to prevent preterm birth in twin gestations: what is the next step forward?
• Vaginal progesterone vs. cervical cerclage for the prevention of preterm birth in women with a sonographic short cervix, previous preterm birth, and singleton gestatio...
• Transient hypothyroidism at 3-year follow-up among cases of congenital hypothyroidism detected by newborn screening.
• The fetal cardiovascular response to increased placental vascular impedance to flow determined with four-dimensional ultrasound using spatiotemporal image correlation ...
• Are infants born by elective cesarean delivery without labor at risk for developing immune disorders later in life?
• Screening for congenital hypothyroidism in newborns transferred to neonatal intensive care.
• Interleukin-33 in the human placenta.
• Evaluation of cervical stiffness during pregnancy using semiquantitative ultrasound elastography.
• Methylome of fetal and maternal monocytes and macrophages at the feto-maternal interface.
• Clinical chorioamnionitis is characterized by changes in the expression of the alarmin HMGB1 and one of its receptors, sRAGE.
• Elephant transcriptome provides insights into the evolution of eutherian placentation.
• Dendrimer-based postnatal therapy for neuroinflammation and cerebral palsy in a rabbit model.
• A dendrimer-based immunosensor for improved capture and detection of tumor necrosis factor-α cytokine.
• Transcriptomics of Maternal and Fetal Membranes Can Discriminate between Gestational-Age Matched Preterm Neonates with and without Cognitive Impairment Diagnosed at 18...
• In Vivo Experiments Reveal the Good, the Bad and the Ugly Faces of sFlt-1 in Pregnancy.
• The vaginal microbiota of pregnant women who subsequently have spontaneous preterm labor and delivery and those with a normal delivery at term.
• The evolution of embryo implantation.
• Intrinsic functional brain architecture derived from graph theoretical analysis in the human fetus.
• Correction: The composition and stability of the vaginal microbiota of normal pregnant women is different from that of non-pregnant women.
• The composition and stability of the vaginal microbiota of normal pregnant women is different from that of non-pregnant women.
• A comparison of gene set analysis methods in terms of sensitivity, prioritization and specificity.

Doctors Specialties

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• Maternal-Fetal Medicine
• Obstetrics
• Gynecology

Accepted Insurances

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Awards

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• Elected Member
• Fellow (FACOG)

Education

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• Yale-New Haven Hospital

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