Assistant Professor of Pediatrics, Boston Children's Hospital
Pediatric Cardiology
Dr. Roger Breitbart, MD
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Roger Breitbart works in the field of Pediatric Cardiology. He attended Harvard Medical School. Harvard Medical School is a one of the best medicals schools. Harvard Medical School has a rank of 1 in research and a 12 in primary care He has 2 awards "Regional Top Doctor" and "Fellow (FACC)". Roger Breitbart is a published physician. He published 38 publications, including: 'Differential rescue of visceral and cardiac defects in Drosophila by vertebrate tinman-related genes.'
Publications
- Survival Data and Predictors of Functional Outcome an Average of 15âYears after the Fontan Procedure: The Pediatric Heart Network Fontan Cohort.
- De novo mutations in histone-modifying genes in congenital heart Disease.
- Comparison of thyroxine and 3,3'',5''-triiodothyronine metabolism in rat kidney and liver homogenates.
- Conversion of thyroxine to triiodothyronine in the anterior pituitary gland and the influence of this process on thyroid status.
- Atherosclerosis: a cancer of the blood vessels?
- Atherosclerosis and cancer: common molecular pathways of Disease development and progression.
- Expression of neutrophil collagenase (matrix metalloproteinase-8) in human atheroma: a novel collagenolytic pathway suggested by transcriptional profiling.
- A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9.
- Conservation of sequence and expression of Xenopus and zebrafish dHAND during cardiac, branchial arch and lateral mesoderm development.
- Differential rescue of visceral and cardiac Defects in Drosophila by vertebrate tinman-related genes.
- Zebrafish: genetic and embryological methods in a transparent vertebrate embryo.
- A new tinman-related gene, nkx2.7, anticipates the expression of nkx2.5 and nkx2.3 in zebrafish Heart and pharyngeal endoderm.
- Three zebrafish MEF2 genes delineate somitic and cardiac muscle development in wild-type and mutant embryos.
- Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice.
- Recent advances in the Laboratory of Molecular and Cellular Cardiology.
- A fourth human MEF2 transcription factor, hMEF2D, is an early marker of the myogenic lineage.
- MEF2C, a MADS/MEF2-family transcription factor expressed in a laminar distribution in cerebral cortex.
- Complete nucleotide sequence of the fast skeletal troponin T gene. Alternatively spliced exons exhibit unusual interspecies divergence.
- Developmentally induced, muscle-specific trans factors control the differential splicing of alternative and constitutive troponin T exons.
- Alternative splicing: a ubiquitous mechanism for the generation of multiple protein isoforms from single genes.
- Intricate combinatorial patterns of exon splicing generate multiple regulated troponin T isoforms from a single gene.
- Alternative splicing is an efficient mechanism for the generation of protein diversity: contractile protein genes as a model system.
- Human myocyte-specific enhancer factor 2 comprises a group of tissue-restricted MADS box transcription factors.
- Etiology, management, and outcome of pediatric pericardial effusions.
- Outcome after repair of atrioventricular Septal defect with tetralogy of Fallot.
- Late status of Fontan patients with persistent surgical fenestration.
- Factors Associated with Serum Brain Natriuretic Peptide Levels after the Fontan Procedure.
- The Fontan patient: inconsistencies in medication therapy across seven pediatric Heart network centers.
- Laboratory measures of exercise capacity and ventricular characteristics and function are weakly associated with functional health status after Fontan procedure.
- De novo copy number variants identify new genes and loci in isolated sporadic tetralogy of Fallot.
- Functional status, Heart rate, and rhythm abnormalities in 521 Fontan patients 6 to 18 years of age.
- Contemporary outcomes after the Fontan procedure: a Pediatric Heart Network multicenter study.
- Functional state of patients with heterotaxy syndrome following the Fontan operation.
- Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice.
- Sarcomeric genes involved in reverse remodeling of the Heart during left ventricular assist device support.
- Right ventricular pseudoaneurysm after modified Norwood procedure.
- Heart block, ventricular tachycardia, and sudden death in ACE2 transgenic mice with downregulated connexins.
Schools
Harvard Medical School
Children39s Hospital Boston
Procedures Preformed
- Cardiac Imaging
- Cardioverter-Defibrillator or Pacemaker Insertion, Removal or Repair
Conditions Treated
- Aortic Valve Disease
- Arrhythmias (incl. Atrial Fibrillation)
- Chronic Pulmonary Heart Diseases (incl. Pulmonary Hypertension)
- Coarctation of the Aorta
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Doctors Specialties
- Pediatric Cardiology
Accepted Insurances
Awards
- Regional Top Doctor
- Fellow (FACC)
Education
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Boston Children's Hospital -
Harvard Medical School
Hospital
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Beth Israel Deaconess Medical Center -
Boston Children's Hospital
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