Assistant Professor of Dermatology, UCLA
Dermatology
Dr. Roger S. Lo, MD
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Roger is an expert in the field of Dermatology. He studied medicine at Weill Cornell Medical College of Cornell University. Weill Cornell Medical College of Cornell University is ranked 18/49 in Research/PrimaryCare. He has 3 awards "Top Doctors:LA Area", "Elected Member" and "Top Doctors:Southern California". Roger S. Lo is also published. He has 33 publications published. The lastest publication: "Determinants of specificity in TGF-beta signal transduction.'
Publications
- Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma.
- Phylogenetic analyses of Melanoma reveal complex patterns of metastatic dissemination.
- Therapy-induced tumour secretomes promote resistance and tumour progression.
- Tunable-combinatorial mechanisms of acquired resistance limit the efficacy of BRAF/MEK cotargeting but result in Melanoma drug addiction.
- COX-2 inhibition prevents the appearance of cutaneous squamous Cell carcinomas accelerated by BRAF inhibitors.
- Pharmacodynamic Effects and Mechanisms of Resistance to Vemurafenib in Patients With Metastatic Melanoma.
- Meeting report from the Society for Melanoma Research 2012 Congress, Hollywood, California.
- Polymer nanofiber-embedded microchips for detection, isolation, and molecular analysis of single circulating melanoma Cells.
- Melanoma prognostics and personalized therapeutics at a crossroad.
- Glucose deprivation activates a metabolic and signaling amplification loop leading to Cell death.
- Receptor tyrosine kinases in Cancer escape from BRAF inhibitors.
- Preexisting MEK1 Exon 3 Mutations in V600E/KBRAF Melanomas Do Not Confer Resistance to BRAF Inhibitors.
- The HSP90 Inhibitor XL888 Overcomes BRAF Inhibitor Resistance Mediated through Diverse Mechanisms.
- RAS mutations in cutaneous squamous-Cell carcinomas in patients treated with BRAF inhibitors.
- Combinatorial Treatments That Overcome PDGFR{beta}-Driven Resistance of Melanoma Cells to V600EB-RAF Inhibition.
- Combination therapy with vemurafenib (PLX4032/RG7204) and metformin in melanoma Cell lines with distinct driver mutations.
- Reversing Melanoma Cross-Resistance to BRAF and MEK Inhibitors by Co-Targeting the AKT/mTOR Pathway.
- Transforming growth factor-beta activation promotes genetic context-dependent invasion of immortalized melanocytes.
- Mixed lineage kinases activate MEK independently of RAF to mediate resistance to RAF inhibitors.
- Detecting Mechanisms of Acquired BRAF Inhibitor Resistance in Melanoma.
- The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-beta receptors.
- Epidermal growth factor signaling via Ras controls the Smad transcriptional co-repressor TGIF.
- TGFbeta signaling in growth control, Cancer, and heritable disorders.
- Multiple modes of repression by the Smad transcriptional corepressor TGIF.
- Ubiquitin-dependent degradation of TGF-beta-activated smad2.
- A Smad transcriptional corepressor.
- Determinants of specificity in TGF-beta signal transduction.
- TbetaR-I(6A) is a candidate tumor susceptibility allele.
- Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation.
- Differential sensitivity of melanoma Cell lines with BRAFV600E mutation to the specific Raf inhibitor PLX4032.
- RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E).
- Combinatorial therapies to overcome B-RAF inhibitor resistance in Melanomas.
Schools
Joan Sanford I Weill Medical College Of Cornell University
Ny Med College
UCLA Med CtrUCLA D Geffen School
Procedures Preformed
- Acne Surgery
- Destruction of Benign Skin Lesion
- Excision of Malignant Skin Lesion
Conditions Treated
- Actinic Keratosis
- Basal Cell Carcinoma
- Benign Skin Lesion
- Carcinoma in Situ of Skin
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Doctors Specialties
- Dermatology
Accepted Insurances
Awards
- Top Doctors:LA Area
- Elected Member
- Top Doctors:Southern California
Education
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UCLA Medical Center -
New York Medical College -
Weill Cornell Medical College of Cornell University
Hospital
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Ronald Reagan UCLA Medical Center -
Santa Monica-UCLA Medical Center and Orthopaedic Hospital
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1326070657 |
| Last Name Of The Provider | LO |
| First Name Of The Provider | ROGER |
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