Deputy Director, Radiology and Imaging Sciences, NIH
Nuclear Medicine
Dr. Ronald D. Neumann, MD
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Ronald Neumann practices Nuclear Medicine. He went to medical school at Yale University School of Medicine. Yale University School of Medicine is a top medical university. Yale University School of Medicine has a rank of 7 in research and a 57 in primary care He received 1 awards: "Whos Who in Medicine and Healthcare". Doctor Ronald D. Neumann, MD is a published doctor and has 99 publications published. The lastest was: 'Phase I study of the pharmacokinetics of a radioimmunoconjugate, 90Y-T101, in patients with CD5-expressing leukemia and lymphoma.'
Publications
- G-Quadruplex Formation Between G-Rich PNA and Homologous Sequences in Oligonucleotides and Supercoiled Plasmid DNA.
- Changes in human pluripotent stem cell gene expression after genotoxic stress exposures.
- PPG Peptide Nucleic Acids that Promote DNA Guanine Quadruplexes.
- Perspective, the one most responsive to change.
- Human embryonic stem cell responses to ionizing radiation exposures: current state of knowledge and future challenges.
- Effect of 5-(125)Iiodo-2'-deoxyuridine uptake on the proliferation and pluripotency of human embryonic stem cells.
- Study of charge transport mechanisms in (125)I-induced DNA damage at various temperatures.
- Targeting DNA g-quadruplex structures with Peptide nucleic acids.
- Quadruplex formation is necessary for stable PNA invasion into duplex DNA of BCL2 promoter region.
- Systems-related facts and consequences in assessing risk from low-level irradiation.
- Base damage immediately upstream from double-strand break ends is a more severe impediment to nonhomologous end joining than blocked 3'-termini.
- Intracellular traffic of oligodeoxynucleotides in and out of the nucleus: effect of exportins and DNA structure.
- Low-level ionizing radiation from noninvasive cardiac imaging: can we extrapolate estimated risks from epidemiologic data to the clinical setting?
- Low-dose cancer risk modeling must recognize up-regulation of protection.
- Assessing DNA structures with 125I radioprobing.
- Tracking radiation exposure from diagnostic imaging devices at the NIH.
- Coincident In Vitro Analysis of DNA-PK-Dependent and -Independent Nonhomologous End Joining.
- Radiation-induced bystander effects in cultured human stem cells.
- Duplex formation at the 5' end affects the quadruplex conformation of the human telomeric repeat overhang in sodium but not in potassium.
- Two principal considerations are needed after low doses of ionizing radiation.
- Phosphorylation of histone H2AX in radiation-induced micronuclei.
- Determination and analysis of site-specific 125I decay-induced DNA double-strand break end-group structures.
- An in vitro nonhomologous end-joining assay using linear duplex oligonucleotides.
- Molecular analysis of base damage clustering associated with a site-specific radiation-induced DNA double-strand break.
- DNA damage produced by 125I-triplex-forming oligonucleotides as a measure of their successful delivery into cell nuclei.
- Characterization of complex apurinic/apyrimidinic-site clustering associated with an authentic site-specific radiation-induced DNA double-strand break.
- DNA uptake and repair enzyme access to transfected DNA is under reported by gene expression.
- A protocol for separation and isolation of small and/or large DNA fragments with high yield using CL4B Sepharose.
- Repair of radiation-induced DNA double-strand breaks is dependent upon radiation quality and the structural complexity of double-strand breaks.
- Iodine-125 radioprobing of E. coli RNA polymerase transcription elongation complexes.
- Repair of sequence-specific 125I-induced double-strand breaks by nonhomologous DNA end joining in mammalian cell-free extracts.
- Absorbed dose and the quantification of physical events at low-dose irradiation of tissue.
- Effects of low doses of ionizing radiation exposures on stress-responsive gene expression in human embryonic stem cells.
- Lessons Learned about Human Stem Cell Responses to Ionizing Radiation Exposures: A Long Road Still Ahead of Us.
- Survival of tumor cells in stem cell preparations and bone marrow of patients with high-risk or metastatic breast cancer after receiving dose-intensive or high-dose ch...
- Repeat unit sequence variation in minisatellites: a novel source of DNA polymorphism for studying variation and mutation by single molecule analysis.
- A malignant melanoma imaging agent: synthesis, characterization, in vitro binding and biodistribution of iodine-125-(2-piperidinylaminoethyl)4-iodobenzamide.
- Detection of pulmonary embolism in man with 111In-labeled autologous platelets.
- Neuropathy associated with acrodermatitis chronica atrophicans. Clinical and morphological features.
- Minisatellite mutation rate variation associated with a flanking DNA sequence polymorphism.
- Transferrin dependence of Ga (NO3)3 inhibition of growth in human-derived small cell lung cancer cells.
- Isolation of human simple repeat loci by hybridization selection.
- Recurrent 2-bp deletion in exon 10c of the NF1 gene in two cases of von Recklinghausen neurofibromatosis.
- Viruses as tools for studies on the molecular biology of mammalian cells.
- Cloned fragments of human adenovirus type-12 DNA.
- Minisatellite mutation frequency in human sperm following radiotherapy.
- Serum HER-2 extracellular domain: relationship with clinicobiological presentation and prognostic value before and after primary treatment in 701 breast cancer patients.
- A simple method for affinity purification of radiolabeled monoclonal antibodies.
- Integration of adenovirus type 2 DNA at a limited number of cellular sites in productively infected cells.
- Radiolabeled peptides and other ligands for receptors overexpressed in tumor cells for imaging neoplasms.
- Streptavidin distribution in metastatic tumors pretargeted with a biotinylated monoclonal antibody: theoretical and experimental pharmacokinetics.
- Radionuclide renography predicts functional changes in patients with renal artery involvement by Takayasu's arteritis.
- Amplification of human minisatellites by the polymerase chain reaction: towards DNA fingerprinting of single cells.
- STS for minisatellite 33.1 (D9S49): direct typing by PCR.
- Determination of the nucleotide sequence for the penton-base gene of human adenovirus type 5.
- The role of gallium-67 tumour scintigraphy in patients with small, non-cleaved cell lymphoma.
- Two-step targeting of experimental lung metastases with biotinylated antibody and radiolabeled streptavidin.
- Pulmonary and oxygen transport effects of intravenously administered endotoxin in normal humans.
- Correspondence Re: Timothy S. Loy, Paul L. Gelven, Dawn Mullins, and Alberto A. Diaz-Arias. Immunostaining for P-glycoprotein in the diagnosis of thyroid carcinomas. M...
- Two unusual cases of metastatic osteosarcoma detected by Tc-99m MDP bone scintigraphy.
- The U.S. Advisory Committee on Human Radiation Experiments.
- Targeting cancer micrometastases with monoclonal antibodies: a binding-site barrier.
- The role of positron emission tomography imaging in early assessment of the antitumor impact of biologics and cytotoxics.
- Iodine-131-metaiodobenzylguanidine scintigraphy in preoperative and postoperative evaluation of paragangliomas: comparison with CT and MRI.
- Pulmonary lymphangioleiomyomatosis: correlation of ventilation-perfusion scintigraphy, chest radiography, and CT with pulmonary function tests.
- Localization of Tc-99m MDP in cystosarcoma phyllodes.
- DNA methylation and viral gene expression in adenovirus-transformed and -infected cells.
- Micropharmacology of monoclonal antibodies in solid tumors: direct experimental evidence for a binding site barrier.
- Gene radiotherapy; gene targeted versus targeted by gene product.
- Radiolabeled products in rat liver and serum after administration of antibody-amide-DTPA-indium-111.
- Evaluation of different methods for the detection of minimal residual disease in blood and bone marrow of patients with primary breast cancer: importance for clinical ...
- Phase I study of the pharmacokinetics of a radioimmunoconjugate, 90Y-T101, in patients with CD5-expressing leukemia and lymphoma.
- Measurement of local Mr 97,000 and 250,000 protein antigen concentration in sections of human melanoma tumor using in vitro quantitative autoradiography.
- Monoclonal antibodies for radioimmunoscintigraphy of breast cancer.
- In vitro complex formation and biodistribution of mouse antitumor monoclonal antibody in cancer patients.
- Collecting duct carcinoma of the kidney.
- Anti-murine antibody response to mouse monoclonal antibodies: clinical findings and implications.
- Comparison of bone marrow dosimetry and toxic effect of high dose 131I-labeled monoclonal antibodies administered to man.
- Quantitation of triple-helix formation using a photo-cross-linkable aryl azide/biotin/oligonucleotide conjugate.
- Development of DNA-based radiopharmaceuticals carrying Auger-electron emitters for antigene radiotherapy.
- Distribution of the 72-kd type IV collagenase in nonneoplastic and neoplastic thyroid tissue.
- Local distribution and concentration of intravenously injected 131I-9.2.27 monoclonal antibody in human malignant melanoma.
- Scintigraphic findings and follow up in Erdheim-Chester disease.
- Parathyroid imaging by Tc/Tl scintigraphy.
- Value of gross cystic disease fluid protein-15 in distinguishing metastatic breast carcinomas among poorly differentiated neoplasms involving the ovary.
- Positive gallium-67 citrate scintigraphy in Wiskott-Aldrich syndrome with malignant lymphoma.
- P-glycoprotein expression is increased in human secretory and gestational endometrium.
- Immunohistochemical detection of P-glycoprotein in endometrial adenocarcinoma.
- Ultrastructural histology correlates with results of thallium-201/technetium-99m parathyroid subtraction scintigraphy.
- Effect of metabolism on retention of indium-111-labeled monoclonal antibody in liver and blood.
- Application of high affinity binding concept to radiolabel avidin with Tc-99m labeled biotin and the effect of pI on biodistribution.
- Targeting of transferrin receptors in nude mice bearing A431 and LS174T xenografts with [18F]holo-transferrin: permeability and receptor dependence.
- Monitoring responses to antiangiogenic agents using noninvasive imaging tests.
- Differential cellular catabolism of 111In, 90Y and 125I radiolabeled T101 anti-CD5 monoclonal antibody.
- Kinetic analysis of muscarinic receptors in human brain and salivary gland in vivo.
- What is new in nuclear medicine imaging?
- Radiotoxicity of iodine-125-labeled oligodeoxyribonucleotides in mammalian cells.
- Genome-wide gene expression changes in normal human fibroblasts in response to low-LET gamma-radiation and high-LET-like 125IUdR exposures.
Doctors Specialties
- Nuclear Medicine
Accepted Insurances
Awards
- Whos Who in Medicine and Healthcare
Education
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Yale University School of Medicine
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