Professor of Pathology, University S Fla College of Medicine
Pathology
Dr. Santo V. Nicosia, MD
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Santo V. Nicosia practices Pathology. He over the years received 2 awards: "America's Top Doctors" and "America's Top Doctors for Cancer". Santo Nicosia is a published doctor and has 101 publications published. The lastest was: 'Effects of raloxifene in a guinea pig model for leiomyomas.'
Publications
- Suppression of epithelial ovarian cancer invasion into the omentum by 1α,25-dihydroxyvitamin D3 and its receptor.
- HDAC6 Deacetylates and Ubiquitinates MSH2 to Maintain Proper Levels of MutSα
- Association Between IHC and MSI Testing to Identify Mismatch Repair-Deficient Patients with Ovarian Cancer.
- Extracellular Signal-regulated Kinase (ERK) Phosphorylates Histone Deacetylase 6 (HDAC6) at Serine 1035 to Stimulate Cell Migration.
- One mouse, one patient paradigm: New avatars of personalized cancer therapy.
- Frequency of mutations in mismatch repair genes in a population-based study of women with ovarian cancer.
- An autoradiographic study of rabbit ovarian surface epithelium before and after ovulation.
- Isolation and ultrastructure of rabbit ovarian mesothelium (surface epithelium).
- Characterization of the Ca2+ responses evoked by ATP and other nucleotides in mammalian brain astrocytes.
- Ofloxacin for the treatment of urinary tract infections and biofilms in spinal cord injury.
- Surface morphology of ovarian mesothelium (surface epithelium) and of other pelvic and extrapelvic mesothelial sites in the rabbit.
- Solubilization and separation of the glucagon receptor and adenylate cyclase in guanine nucleotide-sensitive states.
- Properties of cytosolic proteins that confer vasoactive intestinal polypeptide-sensitivity to rat brain adenylate cyclase.
- Lower efficacy: interaction with an inhibitory receptor or partial agonism?
- Effect of the new calcium antagonist lercanidipine and its enantiomers on the migration and proliferation of arterial myocytes.
- Leukotriene D4-induced activation of smooth-muscle cells from human bronchi is partly Ca2+-independent.
- Identification and characterization of two cysteinyl-leukotriene high affinity binding sites with receptor characteristics in human lung parenchyma.
- Internalization and down-regulation of the prostacyclin receptor in human platelets.
- Effect of estradiol-17 beta on endocervical cytodifferentiation and glycoprotein biosynthesis in the ovariectomized rabbit.
- Luteinization of rabbit preovulatory granulosa cells cultured in vitro in presence of follicular oocytes. I. Growth characteristics and progestin biosynthesis.
- Growth effects of protein hormones on cultured rabbit ovarian surface epithelial cells.
- Role of DNA image cytometry in the follow-up of patients with urinary tract transitional cell carcinoma.
- Metastatic seminoma simulating malignant lymphoma in an HIV infected hemophiliac.
- Evaluation of a frozen section protocol in endometrial carcinoma.
- Cytological analysis of the urn cell complex of Sipunculus nudus before and after serum-induced secretion.
- myc-immortalized microglial cells express a functional platelet-activating factor receptor.
- Effects of GTP on binding of (3H) glucagon to receptors in rat hepatic plasma membranes.
- Scoring acute spinal cord injury: a study of the utility and limitations of five different grading systems.
- Gonadal effects of cancer therapy in girls.
- Gonadal effects of cancer therapy in boys.
- Vascular endothelial growth factor, platelet-derived growth factor, and insulin-like growth factor-1 promote rat aortic angiogenesis in vitro.
- Effects of two international union against cancer standard reference samples of asbestos on cultured rabbit ovarian surface epithelial cells.
- Functional glucocorticoid receptor modulates pancreatic carcinoma growth through an autocrine loop.
- Growth characteristics of rabbit ovarian mesothelial (surface epithelial) cells.
- Predictability of PSA failure in prostate cancer by computerized cytometric assessment of tumoral cell proliferation.
- High serum and ascitic soluble interleukin-2 receptor alpha levels in advanced epithelial ovarian cancer.
- Isolation and characterization of rabbit peritoneal mesothelial cells.
- Regulation and temporal sequence of surface epithelium morphogenesis in the postovulatory rabbit ovary.
- Ancillary techniques in the followup of transitional cell carcinoma: a comparison of cytology, histology and deoxyribonucleic acid image analysis cytometry in 91 patie...
- Vascular endothelial growth factor levels in ovarian cyst fluid correlate with malignancy.
- Fine needle aspiration biopsy of palpable breast lesions. Review and statistical analysis of 1875 cases.
- Loss of p21WAF1/CIP1 accelerates Ras oncogenesis in a transgenic/knockout mammary cancer model.
- Phosphatidylinositol-3-OH Kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha...
- Cell proliferation and apoptosis during development and aging of the rabbit corpus luteum.
- Influence of growth factors on proliferation and morphogenesis of rabbit ovarian mesothelial cells in vitro.
- Experience with the EndoPap device for the cytologic detection of uterine cancer and its precursors: a comparison of the EndoPap with fractional curettage or hysterect...
- Uterine junctional zone: correlation between histologic findings and MR imaging.
- Ovarian mesothelial and extramesothelial cells in interactive culture.
- Estrogen-induced guinea pig model for uterine leiomyomas: do the ovaries protect?
- Abdominal wall metastases from ovarian cancer after laparoscopy.
- Serum soluble interleukin-2 receptor alpha levels in patients with gynecologic cancers: early effect of surgery.
- The medical legal implications of following mammographic breast masses.
- Effects of raloxifene in a guinea pig model for leiomyomas.
- The anatomy of missed breast cancers.
- Lymphatic mapping and sentinel node biopsy in the patient with breast cancer.
- Growth stimulation of ovarian and extraovarian mesothelial cells by corpus luteum extract.
- Imprint cytology of needle-localized breast lesions.
- Estrogen stimulation of ovarian surface epithelial cell proliferation.
- Influence of a corpus luteum tissue extract on rabbit ovarian mesothelial cells.
- Antagonism between PTEN/MMAC1/TEP-1 and androgen receptor in growth and apoptosis of prostatic cancer cells.
- Role of fine needle aspiration cytology after lumpectomy.
- Analysis of p53, p21WAF1, and TGF-beta1 in human ductal adenocarcinoma of the pancreas: TGF-beta1 protein expression predicts longer survival.
- AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells.
- Deacetylation of cortactin by SIRT1 promotes cell migration.
- Chemotherapy plus sequential hormonal therapy for advanced and recurrent endometrial carcinoma: a phase II study.
- Differential diagnosis of endometrial hyperplasia and carcinoma by computerized image cytometry of cell proliferation, apoptosis and Bcl-2 expression.
- Expression of interleukin-2 receptor alpha (IL-2R alpha) mRNA and protein in advanced epithelial ovarian cancer.
- CD44V6 expression in human colorectal carcinoma.
- Cytology of lumpectomy specimens.
- Natural history and clinical evaluation of the lumpectomy scar.
- Antiproliferative and apoptotic effect of ascorbyl stearate in human glioblastoma multiforme cells: modulation of insulin-like growth factor-I receptor (IGF-IR) expres...
- AKT2, a member of the protein kinase B family, is activated by growth factors, v-Ha-ras, and v-src through phosphatidylinositol 3-kinase in human ovarian epithelial ca...
- Local recurrence of breast cancer after cytological evaluation of lumpectomy margins.
- MEKK1 activation of human estrogen receptor alpha and stimulation of the agonistic activity of 4-hydroxytamoxifen in endometrial and ovarian cancer cells.
- Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer.
- Successful therapy of metastatic embryonal carcinoma coexisting with gonadoblastoma in a patient with 46,XY pure gonadal dysgenesis (Swyer's syndrome).
- Touch preparation cytology of breast lumpectomy margins with histologic correlation.
- Analysis of residual cancer after diagnostic breast biopsy: an argument for fine-needle aspiration cytology.
- The phosphoinositide 3-OH kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosis.
- Expression of insulin-like growth factor-1 receptor in human colorectal cancer.
- The insulin-like growth factor 1 receptor induces transformation and tumorigenicity of ovarian mesothelial cells and down-regulates their Fas-receptor expression.
- Prognostic significance of p53, bcl-2, vimentin, and S100 protein-positive Langerhans cells in endometrial carcinoma.
- Cytologic evaluation of lumpectomy margins in patients with ductal carcinoma in situ: clinical outcome.
- Argyrophilic nucleolar organizer regions in breast carcinoma. Correlation with DNA flow cytometry, histopathology, and lymph node status.
- Inhibition of androgen receptor activity by histone deacetylase 4 through receptor SUMOylation.
- Cytokeratin staining for intraoperative evaluation of sentinel lymph nodes in patients with invasive lobular carcinoma.
- Local recurrence in lumpectomy patients after imprint cytology margin evaluation.
- Estradiol-induced hyperplasia in endometrial biopsies from women on hormone replacement therapy.
- Accuracy of intraoperative imprint cytology for sentinel lymph node evaluation in the treatment of breast carcinoma.
- Benign mechanical transport of breast epithelial cells to sentinel lymph nodes.
- BRCA1 and BRCA2 mutations account for a large proportion of ovarian carcinoma cases.
- Survival outcomes in node-negative breast cancer patients evaluated with complete axillary node dissection versus sentinel lymph node biopsy.
- Sampling strategies for tissue microarrays to evaluate biomarkers in ovarian cancer.
- The coupling of epidermal growth factor receptor down regulation by 1alpha,25-dihydroxyvitamin D3 to the hormone-induced cell cycle arrest at the G1-S checkpoint in ov...
- FoxO1 mediates PTEN suppression of androgen receptor N- and C-terminal interactions and coactivator recruitment.
- Urinary levels of Bcl-2 are elevated in ovarian cancer patients.
- Ascorbyl stearate inhibits cell proliferation and tumor growth in human ovarian carcinoma cells by targeting the PI3K/AKT pathway.
- The Akt/PKB pathway: molecular target for cancer drug discovery.
- Expression of thyroid transcription factor-1 in malignant pleural effusions.
- Urinary angiostatin levels are elevated in patients with epithelial ovarian cancer.
Schools
University of Illinois At Chicago College of Medicine
Catholic University Hosps
Michael Reese Hospital and Med Center
University Of Pennsylvania
Doctors Specialties
- Cytopathology
- Pathology
Accepted Insurances
Awards
- America's Top Doctors
- America's Top Doctors for Cancer
Education
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University of Pennsylvania Health System -
University of Cattolica del Sacro Cuore
Hospital
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Tampa General Hospital
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