Physician
Pathology
Dr. Scott B. Shappell, MD
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Scott B. Shappell practices Pathology. He studied medicine at Baylor College of Medicine. Scott Shappell is a published doctor as well. He has 73 publications published. The latest was: Therapist interventions in early sessions of brief supportive-expressive psychotherapy for depression.
Publications
- Comparative analysis of whole mount processing and systematic sampling of radical prostatectomy specimens: pathological outcomes and risk of biochemical recurrence.
- PCA3 urine mRNA testing for prostate carcinoma: patterns of use by community urologists and assay performance in reference laboratory setting.
- Androgen regulated genes in human prostate xenografts in mice: relation to BPH and prostate cancer.
- Incidence and location of prostate and urothelial carcinoma in prostates from cystoprostatectomies: implications for possible apical sparing surgery.
- Clinical utility of prostate carcinoma molecular diagnostic tests.
- Bioluminescence imaging of vascular endothelial growth factor promoter activity in murine mammary tumorigenesis.
- Expression and role of Foxa proteins in prostate cancer.
- Significance of atypical and suspicious small acinar proliferations, and high grade prostatic intraepithelial neoplasia on prostate biopsy: implications for cancer det...
- Use of tissue recombination to predict phenotypes of transgenic mouse models of prostate carcinoma.
- Development and characterization of efficient xenograft models for benign and malignant human prostate tissue.
- Detection and subcellular localization of two 15S-lipoxygenases in human cornea.
- Overexpression of 12/15-lipoxygenase, an ortholog of human 15-lipoxygenase-1, in the prostate tumors of TRAMP mice.
- NE-10 neuroendocrine cancer promotes the LNCaP xenograft growth in castrated mice.
- Adverse prognostic significance of capsular incision with radical retropubic prostatectomy.
- 15-Lipoxygenase-2 expression in benign and neoplastic lung: an immunohistochemical study and correlation with tumor grade and proliferation.
- Prostate pathology of genetically engineered mice: definitions and classification. The consensus report from the Bar Harbor meeting of the Mouse Models of Human Cancer...
- Approaches to understanding the importance and clinical implications of peroxisome proliferator-activated receptor gamma (PPARgamma) signaling in prostate cancer.
- An allograft model of androgen independent prostatic neuroendocrine carcinoma derived from a large probasin promoter-T antigen transgenic mouse line.
- Subcellular localization and tumor-suppressive functions of 15-lipoxygenase 2 (15-LOX2) and its splice variants.
- Primary culture model of peroxisome proliferator-activated receptor gamma activity in prostate cancer cells.
- Elevated expression of 12/15-lipoxygenase and cyclooxygenase-2 in a transgenic mouse model of prostate carcinoma.
- The loss of TGF-beta signaling promotes prostate cancer metastasis.
- Recurrent lupus nephritis in renal transplant recipients revisited: it is not rare.
- Reduced 15S-lipoxygenase-2 expression in esophageal cancer specimens and cells and upregulation in vitro by the cyclooxygenase-2 inhibitor, NS398.
- Peroxisome proliferator-activated receptor gamma and transforming growth factor-beta pathways inhibit intestinal epithelial cell growth by regulating levels of TSC-22.
- Transgenic mouse models for prostate cancer. Identification of an androgen-dependent promoter and creation and characterization of the long probasin promoter-Large T a...
- The free/total prostate-specific antigen ratio (%fPSA) is the best predictor of tumor involvement in the radical prostatectomy specimen among men with an elevated PSA.
- Pathological parameters of radical prostatectomy for clinical stages T1c versus T2 prostate adenocarcinoma: decreased pathological stage and increased detection of tra...
- ET-1 receptor gene expression and distribution in L1 and L2 cells from hypertensive sheep pulmonary artery.
- Percent of cancer in the biopsy set predicts pathological findings after prostatectomy.
- Therapist interventions in early sessions of brief supportive-expressive psychotherapy for depression.
- Nephrotic range proteinuria and hematuria in a white bisexual male.
- Posttransplantation lymphoproliferative disorder in a renal allograft recipient.
- A selective cyclooxygenase-2 inhibitor decreases proteinuria and retards progressive renal injury in rats.
- Primary renal carcinoid tumor.
- G(alpha)i2-deficient mice with colitis exhibit a local increase in memory CD4+ T cells and proinflammatory Th1-type cytokines.
- Adhesion molecules as markers of acute cellular rejection of renal allografts.
- Nephrotic syndrome in a young postpartum woman.
- Monoclonal gammopathy: significance and possible causality in renal disease.
- Thin basement membrane disease with heavy proteinuria or nephrotic syndrome at presentation.
- Cell apoptosis and proliferation in experimental chronic obstructive uropathy.
- TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia.
- Identification of extracellular delta-catenin accumulation for prostate cancer detection.
- Increased expression of delta-catenin/neural plakophilin-related armadillo protein is associated with the down-regulation and redistribution of E-cadherin and p120ctn ...
- Primary neuroendocrine carcinoma of the urethra.
- Disruption of PPARgamma signaling results in mouse prostatic intraepithelial neoplasia involving active autophagy.
- Chronic obstructive uropathy in severe combined immunodeficient (SCID) mice: lymphocyte infiltration is not required for progressive tubulointerstitial injury.
- An adolescent with relapsing nephrotic syndrome: minimal-change disease versus focal-segmental glomerulosclerosis versus C1q nephropathy.
- LFA-1 is sufficient in mediating neutrophil emigration in Mac-1-deficient mice.
- Susceptibility to local and systemic bacterial infections in intercellular adhesion molecule 1-deficient transgenic mice.
- No evidence for reactive oxygen damage in ischemia-reflow injury.
- Glutathione disulfide formation and lipid peroxidation during cardiac ischemia and reflow in the dog in vivo.
- Mac-1 (CD11b/CD18) mediates adherence-dependent hydrogen peroxide production by human and canine neutrophils.
- Comparison of antioxidant and nonantioxidant lipoxygenase inhibitors on neutrophil function. Implications for pathogenesis of myocardial reperfusion injury.
- Neutrophil adherence to isolated adult canine myocytes. Evidence for a CD18-dependent mechanism.
- Neutrophil induced oxidative injury of cardiac myocytes. A compartmented system requiring CD11b/CD18-ICAM-1 adherence.
- Prediction of tumour volume and pathological stage in radical prostatectomy specimens is not improved by taking more prostate needle-biopsy cores.
- Alterations in lipoxygenase and cyclooxygenase-2 catalytic activity and mRNA expression in prostate carcinoma.
- Small intestinal submucosa as a urethral coverage layer.
- Clinical under staging of high risk nonmuscle invasive urothelial carcinoma treated with radical cystectomy.
- 15-Lipoxygenase-2 expression in benign and neoplastic sebaceous glands and other cutaneous adnexa.
- A probasin-large T antigen transgenic mouse line develops prostate adenocarcinoma and neuroendocrine carcinoma with metastatic potential.
- 15S-Hydroxyeicosatetraenoic acid activates peroxisome proliferator-activated receptor gamma and inhibits proliferation in PC3 prostate carcinoma cells.
- Ratio of free-to-total prostate specific antigen correlates with tumor volume in patients with increased prostate specific antigen.
- Reduced 15-lipoxygenase-2 immunostaining in prostate adenocarcinoma: correlation with grade and expression in high-grade prostatic intraepithelial neoplasia.
- Enhanced expression of cyclooxygenase-2 in high grade human transitional cell bladder carcinomas.
- Expression of adhesion molecules in kidney with experimental chronic obstructive uropathy: the pathogenic role of ICAM-1 and VCAM-1.
- Investigation of a second 15S-lipoxygenase in humans and its expression in epithelial tissues.
- 15-lipoxygenase-2 (15-LOX-2) is expressed in benign prostatic epithelium and reduced in prostate adenocarcinoma.
- Forkhead box A1 regulates prostate ductal morphogenesis and promotes epithelial cell maturation.
- Conditional expression of human 15-lipoxygenase-1 in mouse prostate induces prostatic intraepithelial neoplasia: the FLiMP mouse model.
- Tumour volume is an independent predictor of prostate-specific antigen recurrence in patients undergoing radical prostatectomy for clinically localized prostate cancer.
Schools
Baylor University
Doctors Specialties
- Anatomic Pathology
- Pathology
Accepted Insurances
Education
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Baylor College of Medicine
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