Professor, Pediatrics, LSU School of Medicine New Orleans
Pediatrics
Dr. Seth H. Pincus, MD
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Seth H. Pincus, MD is an expert in the field of Pediatrics. He researched medicine at NYU School of Medicine. Seth H. Pincus is also a published doctor. He has 101 publication published. The most recent publication is: Improved reproducibility of ELISA using a static-discharge pad.
Publications
- Improved guanide compounds which bind the CXCR4 co-receptor and inhibit HIV-1 infection.
- Crystal structure and computational modeling of the fab fragment from a protective anti-ricin monoclonal antibody.
- Anti-HIV Double Variable Domain Immunoglobulins Binding Both gp41 and gp120 for Targeted Delivery of Immunoconjugates.
- Fine specificity and cross-reactions of monoclonal antibodies to group B streptococcal capsular polysaccharide type III.
- Inhibition of protein-protein interaction of HER2-EGFR and HER2-HER3 by a rationally designed peptidomimetic.
- Animal Models of Ricin Toxicosis.
- Novel compounds containing multiple guanide groups that bind the HIV coreceptor CXCR4.
- Human CD1D gene expression is regulated by LEF-1 through distal promoter regulatory elements.
- Post-exposure targeting of specific epitopes on ricin toxin abrogates toxin-induced hypoglycemia, hepatic injury, and lethality in a mouse model.
- Use of tissue culture cell lines to evaluate HIV antiviral resistance.
- Double-blind trial of recombinant gamma-interferon versus placebo in the treatment of rheumatoid arthritis. 1989.
- Peptides selected from a phage display library with an HIV-neutralizing antibody elicit antibodies to HIV gp120 in rabbits, but not to the same epitope.
- Oropharyngeal aspiration of ricin as a lung challenge model for evaluation of the therapeutic index of antibodies against ricin A-chain for post-exposure treatment.
- Comparison of different microarray data analysis programs and description of a database for microarray data management.
- Immunological characteristics associated with the protective efficacy of antibodies to ricin.
- A modified SCID mouse model of HIV infection with utility for testing anti-HIV therapies.
- NMR studies of carbohydrates and carbohydrate-mimetic peptides recognized by an anti-group B Streptococcus antibody.
- In vivo efficacy of anti-glycoprotein 41, but not anti-glycoprotein 120, immunotoxins in a mouse model of HIV infection.
- Identification of immunoreactive material in mammoth fossils.
- Identification of hypoglycemia in mice as a surrogate marker of ricin toxicosis.
- Expression of the Memory Marker CD45RO on Helper T Cells in Macaques.
- Antibody to ricin a chain hinders intracellular routing of toxin and protects cells even after toxin has been internalized.
- Vaccinia virus recombinants expressing either the measles virus fusion or hemagglutinin glycoprotein protect dogs against canine distemper virus challenge.
- Recombinant vaccinia virus producing the prM and E proteins of yellow fever virus protects mice from lethal yellow fever encephalitis.
- A novel approach for the evaluation and treatment of psoriasis. Oral or topical use of 1,25-dihydroxyvitamin D3 can be a safe and effective therapy for psoriasis.
- Repaglinide acutely amplifies pulsatile insulin secretion by augmentation of burst mass with no effect on burst frequency.
- A canarypox vector-expressing cytomegalovirus (CMV) phosphoprotein 65 induces long-lasting cytotoxic T cell responses in human CMV-seronegative subjects.
- Comparison of protective immunity elicited by recombinant vaccinia viruses that synthesize E or NS1 of Japanese encephalitis virus.
- Type-specific monoclonal antibody enhances the local phagocytic response to group B streptococcal infection.
- Molecular events leading to picornavirus genome replication.
- Japanese encephalitis virus-vaccinia recombinants produce particulate forms of the structural membrane proteins and induce high levels of protection against lethal JEV...
- Eosinophil adherence to infective larvae of Trichinella spiralis: quantification and modulation.
- Safety and immunogenicity of recombinants based on the genetically-engineered vaccinia strain, NYVAC.
- Effect of nonprotective vaccination on antibody response to subsequent human immunodeficiency virus infection.
- Increased disorderliness and amplified basal and pulsatile aldosterone secretion in patients with primary aldosteronism.
- Interaction of group B streptococcal opacity variants with the host defense system.
- Interaction of IL 1 and TPA in modulation of eosinophil function.
- Antibody-dependent eosinophil-mediated damage to schistosomula of Schistosoma mansoni: lack of requirement for oxidative metabolism.
- Inhibition of IgG-triggered human eosinophil function by IL-4.
- Effect of H chain V region on complement activation by immobilized immune complexes.
- Increase in titer of the naturally occurring human antibody to neuraminidase-treated lymphocytes after influenza.
- A subpopulation of adherent accessory cells bearing both I-A and I-E or C subregion antigens is required for antigen-specific murine T lymphocyte proliferation.
- Immune responses in patients with T-cell lymphoma treated with an anti-idiotype antibody mimicking a highly restricted T-cell antigen.
- Variable regions of antibodies to synthetic polypeptides--III. Antibodies arising in response to administration of anti-idiotope.
- Phenotypic and genotypic characterization of monoclonal anti-digoxin antibodies.
- Characterization of monoclonal antibodies with specificity for DNA and the synthetic polypeptide antigen (T,G)-A-L.
- Removal of digoxin from the circulation using immobilized monoclonal antibodies.
- Characterization of T cells bearing HLA-DR antigens in rheumatoid arthritis.
- Variable regions of antibodies to synthetic polypeptides--I. Characterization of an idiotope expressed on antibodies and T-cell factors.
- Differential impact of age, sex steroid hormones, and obesity on basal versus pulsatile growth hormone secretion in men as assessed in an ultrasensitive chemiluminesce...
- Characterization of monoclonal antidigoxin antibodies immobilized to a solid support.
- Monoclonal anti-(T,G)-A--L antibodies: characterization of fine specificity and idiotype expression.
- Induction of human cytomegalovirus (HCMV)-glycoprotein B (gB)-specific neutralizing antibody and phosphoprotein 65 (pp65)-specific cytotoxic T lymphocyte responses by ...
- Recombinant vaccinia viruses co-expressing dengue-1 glycoproteins prM and E induce neutralizing antibodies in mice.
- 11 Targeting HIV-Infected Cells.
- A simple and sensitive solid-phase radioimmunoassay for the assay of human TSH antibody. Use in screening hybridoma cell lines.
- Human immunoglobulin heavy-chain-variable (VH) region gene families defined by hybridization with cloned human and murine VH-genes.
- Variants selected by treatment of human immunodeficiency virus-infected cells with an immunotoxin.
- Differences in the antibody response to human immunodeficiency virus-1 envelope glycoprotein (gp160) in infected laboratory workers and vaccinees.
- Improved reproducibility of ELISA using a static-discharge pad.
- Experimental support for an immunological approach to the search for life on other planets.
- Anti-human immunodeficiency virus immunoconjugates.
- Temporal analysis of the antibody response to HIV envelope protein in HIV-infected laboratory workers.
- Absolute requirement for complement in monoclonal IgM antibody-mediated protection against experimental infection with type III group B streptococci.
- Treatment of experimental group B streptococcal infection with hybridoma antibody.
- The effect of hybridoma antibody administration upon neutrophil kinetics during experimental type III group B streptococcal sepsis.
- Alteration in H chain V region affects complement activation by chimeric antibodies.
- Studies on antigen binding by intact and hinge-deleted chimeric antibodies.
- Variable regions of antibodies to synthetic polypeptides. II. Analysis of variable region genes encoding antibodies specific for (T,G)-A--L.
- Secretory process regularity monitors neuroendocrine feedback and feedforward signaling strength in humans.
- AZT demonstrates anti-HIV-1 activity in persistently infected cell lines: implications for combination chemotherapy and immunotherapy.
- Variable region differences affect antibody binding to immobilized but not soluble antigen.
- Production of antisera specific for idiotype(s) of murine anti-(T,G)-A--L antibodies.
- Mechanisms of bacterial opsonization by immune globulin intravenous: correlation of complement consumption with opsonic activity and protective efficacy.
- Idiotypic analysis of hybridoma antibodies to branched synthetic polymer (Tyr, Glu)-Ala-Lys: idiotypic relationship with antibodies to linear random polymer (Glu60, Al...
- Protective efficacy of hybridoma type-specific antibody against experimental infection with group-B Streptococcus.
- Immunologic cross-reaction between HIV type 1 p17 and Mycoplasma hyorhinis variable lipoprotein.
- Soluble CD4 enhances the efficacy of immunotoxins directed against gp41 of the human immunodeficiency virus.
- Use of a focal infectivity assay for testing susceptibility of HIV to antiviral agents.
- Molecular preservation in Late Cretaceous sauropod dinosaur eggshells.
- Humoral immune responses to homologous envelope peptides in vaccinees and lab workers infected with HIV.
- Protective efficacy of nonneutralizing monoclonal antibodies in acute infection with murine leukemia virus.
- Immunoselection of B cell hybridomas with anti-idiotypic antisera to study the role of heavy and light chains for idiotype expression and antibody activity.
- Unique insertion sequence and pattern of CD4 expression in variants selected with immunotoxins from human immunodeficiency virus type 1-infected T cells.
- Processing of the envelope glycoprotein gp160 in immunotoxin-resistant cell lines chronically infected with human immunodeficiency virus type 1.
- Epitope mapping and topology of baculovirus-expressed HIV-1 gp160 determined with a panel of murine monoclonal antibodies.
- Therapeutic potential of anti-HIV immunotoxins.
- In vitro efficacy of anti-HIV immunotoxins targeted by various antibodies to the envelope protein.
- Treatment of HIV tissue culture infection with monoclonal antibody-ricin A chain conjugates.
- In vivo administration of interferon-gamma to patients with rheumatoid arthritis decreases numbers of circulating B cells.
- Protective effects of anti-ricin A-chain antibodies delivered intracellularly against ricin-induced cytotoxicity.
- Preclinical toxicity and efficacy testing of RiVax, a recombinant protein vaccine against ricin.
- Protective efficacy of IgM monoclonal antibodies in experimental group B streptococcal infection is a function of antibody avidity.
- Vaccine-specific antibody responses induced by HIV-1 envelope subunit vaccines.
- Influence of endosome-destabilizing peptides on efficacy of anti-HIV immunotoxins.
- Spontaneous activation of human immunodeficiency virus type 1 in an immunotoxin-resistant variant T cell line.
- Initial studies of the molecular basis of peptide mimicry of group B streptococcal type III capsular polysaccharide.
- Double-blind trial of recombinant gamma-interferon versus placebo in the treatment of rheumatoid arthritis.
- In vivo testing of anti-HIV immunotoxins.
- Peptide ligands that bind IgM antibodies and block interaction with antigen.
Schools
New York University
Doctors Specialties
- Pediatrics
Accepted Insurances
Education
-
University of Utah -
NYU School of Medicine
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