Professor, Anesthesiology, University of Virginia School of Medicine
Anesthesiology
Dr. Slobodan M. Todorovic, MD
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Doctor Slobodan M. Todorovic, MD is an expert in the field of Anesthesiology. Slobodan Todorovic is also a published doctor. He has 76 paper published. The most recent paper is: Properties of Ba2+ currents arising from human alpha1E and alpha1Ebeta3 constructs expressed in HEK293 cells: physiology, pharmacology, and comparison to native T-type... He accepts Medicare.
Publications
- Hyperexcitability of rat thalamocortical networks after exposure to general anesthesia during brain development.
- Inhibition of CaV3.2 T-type calcium channels in peripheral sensory neurons contributes to analgesic properties of epipregnanolone.
- Targeting of CaV3.2 T-type calcium channels in peripheral sensory neurons for the treatment of painful diabetic neuropathy.
- Reversal of neuropathic pain in diabetes by targeting glycosylation of Ca(V)3.2 T-type calcium channels.
- Redox Regulation of Neuronal Voltage-Gated Calcium Channels.
- Immunohistological demonstration of CaV3.2 T-type voltage-gated calcium channel expression in soma of dorsal root ganglion neurons and peripheral axons of rat and mouse.
- Neuropathic pain: role for presynaptic T-type channels in nociceptive signaling.
- Presynaptic CaV3.2 Channels Regulate Excitatory Neurotransmission in Nociceptive Dorsal Horn Neurons.
- Inhibition of T-type calcium current in rat thalamocortical neurons by isoflurane.
- General Anesthesia Causes Long-term Impairment of Mitochondrial Morphogenesis and Synaptic Transmission in Developing Rat Brain.
- TTA-P2 is a Potent and Selective Blocker of T-type Calcium Channels in Rat Sensory Neurons and a Novel Antinociceptive Agent.
- Are neuronal voltage-gated calcium channels valid cellular targets for general anesthetics?
- Isoflurane modulates neuronal excitability of the nucleus reticularis thalami in vitro.
- A modeling study of T-type Ca2+ channel gating and modulation by L-cysteine in rat nociceptors.
- Mechanisms of inhibition of T-type calcium current in the reticular thalamic neurons by 1-octanol: implication of the protein kinase C pathway.
- Selective T-type calcium channel blockade alleviates hyperalgesia in ob/ob mice.
- Molecular mechanisms of lipoic acid modulation of T-type calcium channels in pain pathway.
- Mechanisms and functional significance of inhibition of neuronal T-type calcium channels by isoflurane.
- Isoflurane-sensitive presynaptic R-type calcium channels contribute to inhibitory synaptic transmission in the rat thalamus.
- Upregulation of the T-type calcium current in small rat sensory neurons after chronic constrictive injury of the sciatic nerve.
- Inhibition of T-type calcium current in the reticular thalamic nucleus by a novel neuroactive steroid.
- Molecular mechanisms of subtype-specific inhibition of neuronal T-type calcium channels by ascorbate.
- Reducing agents sensitize C-type nociceptors by relieving high-affinity zinc inhibition of T-type calcium channels.
- Regulation of T-type calcium channels in the peripheral pain pathway.
- Functional regulation of T-type calcium channels by s-nitrosothiols in the rat thalamus.
- Cell-specific alterations of T-type calcium current in painful diabetic neuropathy enhance excitability of sensory neurons.
- Is there a role for T-type calcium channels in peripheral and central pain sensitization?
- The endogenous redox agent L-cysteine induces T-type Ca2+ channel-dependent sensitization of a novel subpopulation of rat peripheral nociceptors.
- 5beta-reduced neuroactive steroids are novel voltage-dependent blockers of T-type Ca2+ channels in rat sensory neurons in vitro and potent peripheral analgesics in vivo.
- CaV3.2 T-Type Calcium Channels in Peripheral Sensory Neurons Are Important for Mibefradil-Induced Reversal of Hyperalgesia and Allodynia in Rats with Painful Diabetic ...
- Pharmacological characterization of 5-hydroxytryptamine2 and 5-hydroxytryptamine3 receptors in rat dorsal root ganglion cells.
- Hyperkalemic periodic paralysis: rapid molecular diagnosis and relationship of genotype to phenotype in 12 families.
- Molecular genetic and genetic correlations in sodium channelopathies: lack of founder effect and evidence for a second gene.
- Pharmacological properties of T-type Ca2+ current in adult rat sensory neurons: effects of anticonvulsant and anesthetic agents.
- Nitrous oxide (laughing gas) is an NMDA antagonist, neuroprotectant and neurotoxin.
- [What do we know about anesthetic mechanisms?: hypnosis, unresponsiveness to surgical incision and amnesia].
- Redox modulation of T-type calcium channels in rat peripheral nociceptors.
- Properties of Ba2+ currents arising from human alpha1E and alpha1Ebeta3 constructs expressed in HEK293 cells: physiology, pharmacology, and comparison to native T-type...
- Variation in IH, IIR, and ILEAK between acutely isolated adult rat dorsal root ganglion neurons of different size.
- Effect of nitrous oxide on excitatory and inhibitory synaptic transmission in hippocampal cultures.
- Cationic modulation of 5-HT2 and 5-HT3 receptors in rat sensory neurons: the role of K+, Ca2+ and Mg2+.
- Anticonvulsants but not general anesthetics have differential blocking effects on different T-type current variants.
- The anesthetic steroid (+)-3alpha-hydroxy-5alpha-androstane-17beta-carbonitrile blocks N-, Q-, and R-type, but not L- and P-type, high voltage-activated Ca2+ current i...
- The role of T-type calcium channels in epilepsy and pain.
- Enantioselective blockade of T-type Ca2+ current in adult rat sensory neurons by a steroid that lacks gamma-aminobutyric acid-modulatory activity.
- Ca(v)3.2 channel is a molecular substrate for inhibition of T-type calcium currents in rat sensory neurons by nitrous oxide.
- 5alpha-reduced neuroactive steroids alleviate thermal and mechanical hyperalgesia in rats with neuropathic pain.
- Targeted next-generation sequencing of a 12.5 Mb homozygous region reveals ANO10 mutations in patients with autosomal-recessive cerebellar ataxia.
- Clinical case report atypical myopathy in a young girl with 91 CTG repeats in DM1 locus and a positive DM1 family history.
- Proximal dystrophin gene deletions and protein alterations in becker muscular dystrophy.
- Epidemiology of myotonic dystrophy type 1 (Steinert disease) in Belgrade (Serbia).
- Eosinophilic myositis as presenting symptom in gamma-sarcoglycanopathy.
- [Epidemiology of myotonic dystrophy type 1 in the population of central Serbia].
- The recurrence risk of ischemic stroke in childhood.
- 250 CTG repeats in DMPK is a threshold for correlation of expansion size and age at onset of juvenile-adult DM1.
- [Clinical course and prognosis in hypoxic-ischemic encephalopathy].
- [Duchenne''s and Becker''s muscular dystrophy: analysis of phenotype-genotype correlation in 28 patients] ].
- Mechanical and thermal antinociception in rats following systemic administration of mibefradil, a T-type calcium channel blocker.
- Redox modulation of peripheral T-type Ca2+ channels in vivo: alteration of nerve injury-induced thermal hyperalgesia.
- Mechanical and thermal anti-nociception in rats after systemic administration of verapamil.
- Potent analgesic effects of anticonvulsants on peripheral thermal nociception in rats.
- Different kinetic properties of two T-type Ca2+ currents of rat reticular thalamic neurones and their modulation by enflurane.
- New evidence that both T-type calcium channels and GABAA channels are responsible for the potent peripheral analgesic effects of 5alpha-reduced neuroactive steroids.
- Contrasting anesthetic sensitivities of T-type Ca2+ channels of reticular thalamic neurons and recombinant Ca(v)3.3 channels.
- Role of voltage-gated calcium channels in ascending pain pathways.
- Differential effects of endogenous cysteine analogs on peripheral thermal nociception in intact rats.
- The role of peripheral T-type calcium channels in pain transmission.
- CaV3.2 is the major molecular substrate for redox regulation of T-type Ca2+ channels in the rat and mouse thalamus.
- Are neuroactive steroids promising therapeutic agents in the management of acute and chronic pain?
- In vivo silencing of the Ca(V)3.2 T-type calcium channels in sensory neurons alleviates hyperalgesia in rats with streptozocin-induced diabetic neuropathy.
- Mechanisms of inhibition of CaV3.1 T-type calcium current by aliphatic alcohols.
- Free radical signalling underlies inhibition of CaV3.2 T-type calcium channels by nitrous oxide in the pain pathway.
- T-type voltage-gated calcium channels as targets for the development of novel pain therapies.
- The role of T-type calcium channels in peripheral and central pain processing.
- Molecular and biophysical basis of glutamate and trace metal modulation of voltage-gated Cav2.3 calcium channels.
Schools
University of Illinois At Chicago College of Medicine
Northwestern University
Wash University Barnes Hospital
Wash University
Doctors Specialties
- Anesthesiology
Accepted Insurances
Education
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Washington University - Barnes-Jewish Hospital -
University of Belgrade Faculty of Medicine
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1417090267 |
| Last Name Of The Provider | TODOROVIC |
| First Name Of The Provider | SLOBODAN |
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