Physician
Pathology
Dr. Stefan Costinean, MD
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Stefan Costinean practices Pathology. Stefan Costinean is also a published doctor. He has 36 paper published. The most recent paper is: Pluripotent Stem Cell miRNAs and Metastasis in Invasive Breast Cancer.
Publications
- Pluripotent Stem Cell miRNAs and Metastasis in Invasive Breast Cancer.
- microRNA 29 Targets NKRF and Claudin 1 to Increase Intestinal Permeability.
- Protective role of miR-155 in breast cancer through RAD51 targeting impairs homologous recombination after irradiation.
- Hepatic Loss of miR-122 Predisposes Mice to Hepatobiliary Cyst and HCC upon Diethylnitrosamine Exposure.
- Overexpression of miR-155 causes expansion, arrest in terminal differentiation and functional activation of mouse natural killer cells.
- miR-155 targets histone deacetylase 4 (HDAC4) and impairs transcriptional activity of B-cell lymphoma 6 (BCL6) in the Eμ-miR-155 transgenic mouse model.
- Primary intrathyroidal paraganglioma: histopathology and novel molecular alterations.
- miR-29ab1 Deficiency Identifies a Negative Feedback Loop Controlling Th1 Bias That Is Dysregulated in Multiple Sclerosis.
- Regulation of acute graft-versus-host disease by microRNA-155.
- Hepatic miR-29ab1 expression modulates chronic hepatic injury.
- MicroRNA Profiles Discriminate among Colon Cancer Metastasis.
- Tcl1 interacts with Atm and enhances NF-kB activation in hematological malignancies.
- microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer.
- Mutator activity induced by microRNA-155 (miR-155) links inflammation and cancer.
- Common fragile site tumor suppressor genes and corresponding mouse models of cancer.
- Loss of metallothionein predisposes mice to diethylnitrosamine-induced hepatocarcinogenesis by activating NF-kappaB target genes.
- Aberrant expression of DNA damage response proteins is associated with breast cancer subtype and clinical features.
- Chronic lymphocytic leukemia modeled in mouse by targeted miR-29 expression.
- Reprogramming of miRNA networks in cancer and leukemia.
- Modulation of mismatch repair and genomic stability by miR-155.
- miR-221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation.
- Karyotype-specific microRNA signature in chronic lymphocytic leukemia.
- Src homology 2 domain-containing inositol-5-phosphatase and CCAAT enhancer-binding protein beta are targeted by miR-155 in B cells of Emicro-MiR-155 transgenic mice.
- Fragile histidine triad protein, WW domain-containing oxidoreductase protein Wwox, and activator protein 2gamma expression levels correlate with basal phenotype in bre...
- MicroRNAs, the immune system and rheumatic disease.
- Hmga1 null mice are less susceptible to chemically induced skin carcinogenesis.
- Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock.
- MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B.
- Wwox suppresses prostate cancer cell growth through modulation of ErbB2-mediated androgen receptor signaling.
- Targeted deletion of Wwox reveals a tumor suppressor function.
- Genetic ablation of Ptprj, a mouse cancer susceptibility gene, results in normal growth and development and does not predispose to spontaneous tumorigenesis.
- Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice.
- Effect of rapamycin on mouse chronic lymphocytic leukemia and the development of nonhematopoietic malignancies in Emu-TCL1 transgenic mice.
- Regulation of cell size and contractile function by AKT in cardiomyocytes.
- Chemoembolization in the treatment of metastatic ileocolic carcinoid.
Doctors Specialties
- Pathology
Accepted Insurances
Education
-
Ohio State University Hospital
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