Professor of Medicine, Professor of Oncology, Johns Hopkins University School of Medicine
Gastroenterology
Dr. Stephen J. Meltzer, MD
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Stephen Meltzer practices Gastroenterology. He studied medicine at University at Buffalo, School of Medicine and Biomedical Sciences. He received awards:"CMS Meaningful Use Stage 1 Certification" and "Elected Member". Stephen J. Meltzer, MD has written publications. He has 87 publications published with PubMed. The lastest publication is: 'Long non-coding antisense RNA KRT7-AS is activated in gastric cancers and supports cancer cell progression by increasing KRT7 expression.' Stephen Meltzer is registered with Medicare.
Publications
- Klotho: a tumor suppressor and modulator of the Wnt/β-catenin pathway in human hepatocellular carcinoma.
- Long non-coding antisense RNA KRT7-AS is activated in gastric Cancers and supports Cancer cell progression by increasing KRT7 expression.
- LINE-1 expression and retrotransposition in Barrett's Esophagus and esophageal carcinoma.
- Differential methylation of the promoter and first exon of the RASSF1A gene in hepatocarcinogenesis.
- Human bile contains microRNA-laden extracellular vesicles that can be used for cholangiocarcinoma diagnosis.
- Effects of Vitamin D3 stimulation of Thioredoxin Interacting Protein in hepatocellular carcinoma.
- Long non-coding RNA HNF1A-AS1 regulates proliferation and migration in oesophageal adenocarcinoma cells.
- MicroRNA-224 Negatively Regulates p21 Expression During Late Neoplastic Progression in Inflammatory Bowel Disease.
- Prohibitin Attenuates Colitis-Associated Tumorigenesis in Mice by Modulating p53 and STAT3 Apoptotic Responses.
- MicroRNAs in Pathogenesis, Diagnosis, and Treatment of Gastroesophageal Cancers.
- MicroRNA-21 inhibits Serpini1, a gene with novel tumour suppressive effects in gastric Cancer.
- ( 32) PATP inhibits the growth of xenografted tumors in nude mice.
- Epigenomic program of Barrett's-associated neoplastic progression reveals possible involvement of insulin signaling pathways.
- MicroRNA involvement in esophageal carcinogenesis.
- Aberrant methylation of the PTPRO gene in peripheral blood as a potential biomarker in esophageal squamous cell carcinoma patients.
- Colorectal cancers with microsatellite instability display unique miRNA profiles.
- Unique patterns of CpG island methylation in inflammatory bowel disease-associated Colorectal cancers.
- Germline mutations in MSR1, ASCC1, and CTHRC1 in patients with Barrett Esophagus and esophageal adenocarcinoma.
- Strong Inhibition of Xenografted Tumor Growth by Low-Level Doses of [32P]ATP.
- Novel candidate Colorectal cancer biomarkers identified by methylation microarray-based scanning.
- A DNA methylation fingerprint of 1,628 human samples.
- Genetic variation in DNA-repair pathways and response to radiochemotherapy in esophageal adenocarcinoma: a retrospective cohort study of the Eastern Cooperative Oncolo...
- Widespread hypomethylation occurs early and synergizes with gene amplification during esophageal carcinogenesis.
- Methylation of the CpG Sites Only on the Sense Strand of the APC Gene Is Specific for Hepatocellular Carcinoma.
- Dynamic changes in the expression of MicroRNA-31 during inflammatory bowel Disease-associated neoplastic transformation.
- Polo-like kinase 1 regulates cell proliferation and is targeted by miR-593* in esophageal Cancer.
- SILAC-based quantitative proteomic approach to identify potential biomarkers from the esophageal squamous cell carcinoma secretome.
- Relation between normal rectal methylation, smoking status, and the presence or absence of Colorectal adenomas.
- Identification of microRNAs associated with ileal and colonic Crohn's Disease.
- Chromosomal abnormalities and novel disease-related regions in progression from Barrett's Esophagus to esophageal adenocarcinoma.
- Honey, I shrunk the telomere: UC speeds aging.
- Epigenetic events in gastrointestinal Cancer.
- A multicenter, double-blinded validation study of methylation biomarkers for progression prediction in Barrett's Esophagus.
- MicroRNA-21 is overexpressed in human cholangiocarcinoma and regulates programmed cell death 4 and tissue inhibitor of metalloproteinase 3.
- The miR-106b-25 polycistron, activated by genomic amplification, functions as an oncogene by suppressing p21 and Bim.
- Screening for microsatellite instability identifies frequent 3'-untranslated region mutation of the RB1-inducible coiled-coil 1 gene in colon tumors.
- Silencing of claudin-11 is associated with increased invasiveness of gastric Cancer cells.
- Promoter hypermethylation of CDH13 is a common, early event in human esophageal adenocarcinogenesis and correlates with clinical risk factors.
- Pituitary tumor-transforming 1 increases cell motility and promotes lymph node metastasis in esophageal squamous cell carcinoma.
- Hypermethylation of the somatostatin promoter is a common, early event in human esophageal carcinogenesis.
- Hypermethylation of the AKAP12 promoter is a biomarker of Barrett's-associated esophageal neoplastic progression.
- Three-tiered risk stratification model to predict progression in Barrett's Esophagus using epigenetic and clinical features.
- Generation of small 32P-labeled peptides as a potential approach to Colorectal cancer therapy.
- Hypermethylation of tachykinin-1 is a potential biomarker in human esophageal Cancer.
- Rare CpG island methylator phenotype in Ulcerative colitis-associated neoplasias.
- Sparse logistic regression with Lp penalty for biomarker identification.
- Urethral stromal tumor with pacemaker cell phenotype.
- Novel decapeptides that bind avidly and deliver radioisotope to colon Cancer cells.
- Rarity of Somatic Mutation and Frequency of Normal Sequence Variation Detected in Sporadic Colon Adenocarcinoma Using High-Throughput cDNA Sequencing.
- Beyond Field Effect: Analysis of Shrunken Centroids in Normal Esophageal Epithelia Detects Concomitant Esophageal Adenocarcinoma.
- Reprimo methylation is a potential biomarker of Barrett's-Associated esophageal neoplastic progression.
- A genome-wide search identifies epigenetic silencing of somatostatin, tachykinin-1, and 5 other genes in colon Cancer.
- RAB32 hypermethylation and microsatellite instability in Gastric and endometrial adenocarcinomas.
- Thapsigargin resistance in human prostate Cancer cells.
- Promoter methylation and response to chemotherapy and radiation in esophageal Cancer.
- Polo-like kinase and survivin are esophageal tumor-specific promoters.
- A review of the genomics of gastric Cancer.
- Aberrant promoter methylation of multiple genes during multistep pathogenesis of Colorectal cancers.
- CpG island hypermethylation in progression of esophageal and gastric Cancer.
- The molecular signature of normal squamous esophageal epithelium identifies the presence of a field effect and can discriminate between patients with Barrett's esophag...
- Aberrant methylation of Reprimo in human malignancies.
- Molecular phenotype of inflammatory bowel disease-associated Neoplasms with microsatellite instability.
- Prediction of survival in patients with esophageal carcinoma using artificial neural networks.
- Prediction of lymph node metastasis with use of artificial neural networks based on gene expression profiles in esophageal squamous cell carcinoma.
- Spermine oxidation induced by Helicobacter pylori results in apoptosis and DNA damage: implications for Gastric carcinogenesis.
- Activin type II receptor restoration in ACVR2-deficient colon Cancer cells induces transforming growth factor-beta response pathway genes.
- Esophagin and proliferating cell nuclear antigen (PCNA) are biomarkers of human esophageal neoplastic progression.
- Transcriptional responses of Intestinal epithelial cells to infection with Vibrio cholerae.
- Identification of genes uniquely involved in frequent microsatellite instability colon carcinogenesis by expression profiling combined with epigenetic scanning.
- Biomarkers of esophageal adenocarcinoma and Barrett's Esophagus.
- An unsupervised approach to identify molecular phenotypic components influencing breast Cancer features.
- Loss of heterozygosity and mutational analyses of the ACTRII gene locus in human Colorectal tumors.
- The impact of microsatellite instability on the molecular phenotype of Colorectal tumors.
- Aberrant methylation of the HPP1 gene in ulcerative colitis-associated Colorectal carcinoma.
- Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma.
- Morphological and molecular heterogeneity within nonmicrosatellite instability-high Colorectal cancer.
- Hypermethylation of HPP1 is associated with hMLH1 hypermethylation in Gastric adenocarcinomas.
- Correspondence re: P. Laiho et al., Low-level microsatellite instability in most Colorectal carcinomas. Cancer Res., 62: 1166-1170, 2002.
- Instabilotyping reveals unique mutational spectra in microsatellite-unstable gastric Cancers.
- Aberrant methylation of the CDH13 (H-cadherin) promoter region in Colorectal cancers and adenomas.
- Artificial neural networks and gene filtering distinguish between global gene expression profiles of Barrett's Esophagus and esophageal cancer.
- Activation of the esophagin promoter during esophageal epithelial cell differentiation.
- Artificial neural networks distinguish among subtypes of neoplastic Colorectal lesions.
- Hypermethylation of the p14(ARF) gene in ulcerative colitis-associated Colorectal carcinogenesis.
- Amplified RNA for gene array hybridizations.
- Genome-wide and gene-specific epigenomic platforms for hepatocellular carcinoma biomarker development trials.
Schools
State University of New York At Buffalo
Tulane University
University Tex Med Br
Lenox Hill Hospital
University Of Colorado
Procedures Preformed
- Colonoscopy, Proctosigmoidoscopy, and Sigmoidoscopy
- Endoscopy (Esophagus, Stomach, Small Intestine)
Conditions Treated
- Abdominal Pain
- Anemia
- Barrett's Esophagus
- Benign Neoplasm of the Digestive System
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Doctors Specialties
- Gastroenterology
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
- Elected Member
Education
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Lenox Hill Hospital -
University of Colorado -
University of Texas Medical Branch Hospitals -
Tulane University -
University at Buffalo, School of Medicine and Biomedical Sciences
Hospital
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Johns Hopkins Hospital
Drug Facts
| NPI NUMBER | 1679511430 | |
| NPPES Provider LastName | MELTZER | |
| NPPES Provider FirstName | STEPHEN | |
| NPPES Provider ZIPCode | 21287 | |
| NPPES Provider State | MD | |
| Specialty Description | Gastroenterology | |
| Total Claim Count | 82.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1679511430 |
| Last Name Of The Provider | MELTZER |
| First Name Of The Provider | STEPHEN |
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