Professor, Neurology, UCSF School of Medicine
Neurology
Dr. Stephen M. Massa, MD
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Stephen M. Massa practices Neurology. He went to University of Rochester School of Medicine and Dentistry. Dr. Stephen M. Massa is also published. He has 68 publications published. The lastest publication: "Deficient LAR expression decreases basal forebrain cholinergic neuronal size and hippocampal cholinergic innervation.'
Publications
- Amelioration of cisplatin-induced experimental Peripheral neuropathy by a small molecule targeting p75(NTR.)
- Small Molecule p75NTR Ligands Reduce Pathological Phosphorylation and Misfolding of Tau, Inflammatory Changes, Cholinergic Degeneration, and Cognitive Deficits in AβPP...
- A Small Molecule TrkB Ligand Reduces Motor Impairment and Neuropathology in R6/2 and BACHD Mouse Models of Huntington's Disease.
- A Small Molecule P75(NTR) Ligand Protects Neurogenesis after Traumatic Brain Injury.
- A small molecule p75(NTR) ligand prevents cognitive deficits and neurite degeneration in an Alzheimer's mouse model.
- Oral administration of a small molecule targeted to block proNGF binding to p75 promotes myelin sparing and functional recovery after Spinal cord injury.
- Delayed Administration of a Small Molecule Tropomyosin-Related Kinase B Ligand Promotes Recovery After Hypoxic-Ischemic Stroke.
- Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents.
- The p75 neurotrophin receptor promotes amyloid-beta(1-42)-induced neuritic dystrophy in vitro and in vivo.
- Small molecule, non-peptide p75 ligands inhibit Abeta-induced neurodegeneration and synaptic impairment.
- LAR protein tyrosine phosphatase receptor associates with TrkB and modulates neurotrophic signaling pathways.
- Protein-tyrosine phosphatase (PTP) wedge domain peptides: a novel approach for inhibition of PTP function and augmentation of protein-tyrosine kinase function.
- Small, nonpeptide p75NTR ligands induce survival signaling and inhibit proNGF-induced death.
- Clioquinol down-regulates mutant huntingtin expression in vitro and mitigates pathology in a Huntington's Disease mouse model.
- Neuroprotective strategies in Alzheimer's Disease.
- A candidate chimeric mammalian mRNA transcript is derived from distinct chromosomes and is associated with nonconsensus splice junction motifs.
- Leukocyte antigen-related protein tyrosine phosphatase receptor: a small ectodomain isoform functions as a homophilic ligand and promotes neurite outgrowth.
- Alzheimer's therapeutics: neurotrophin domain small molecule mimetics.
- Alzheimer's therapeutics: neurotrophin small molecule mimetics.
- Signaling through Rho GTPase pathway as viable drug target.
- Injury-induced neurogenesis in Bax-deficient mice: evidence for regulation by voltage-gated potassium channels.
- Small molecule neurotrophin receptor ligands: novel strategies for targeting Alzheimer''s Disease mechanisms.
- Small molecule modulation of p75 neurotrophin receptor functions.
- Anti-cancer drug induced neurotoxicity and identification of Rho pathway signaling modulators as potential neuroprotectants.
- Neurotrophin receptor-based strategies for Alzheimer''s Disease.
- Modulation of p75-dependent motor neuron death by a small non-peptidyl mimetic of the neurotrophin loop 1 domain.
- Small molecule approaches for promoting neurogenesis.
- Neurotrophin-based strategies for neuroprotection.
- Adaptable modification of adenoviral tropism using a bifunctional ligand protein.
- The leukocyte common antigen-related protein tyrosine phosphatase receptor regulates regenerative neurite outgrowth in vivo.
- Leukocyte common antigen-related tyrosine phosphatase receptor: increased expression and neuronal-type splicing in breast cancer Cells and tissue.
- Leukocyte common-antigen-related tyrosine phosphatase receptor: altered expression of mRNA and protein in the New England Deaconess Hospital rat line exhibiting sponta...
- Deficient LAR expression decreases basal forebrain cholinergic neuronal size and hippocampal cholinergic innervation.
- cDNA cloning and expression of stress-inducible rat hsp70 in normal and injured rat brain.
- Cloning of rat grp75, an hsp70-family member, and its expression in normal and ischemic brain.
- Phencyclidine induction of the hsp 70 stress gene in injured pyramidal neurons is mediated via Multiple receptors and voltage gated calcium channels.
- Heat-shock protein protection.
- Global ischemia induces apoptosis-associated genes in hippocampus.
- Heme-oxygenase-1 induction in glia throughout rat brain following experimental subarachnoid hemorrhage.
- Focal hyperexpression of hemeoxygenase-1 protein and messenger RNA in rat brain caused by Cellular stress following subarachnoid injections of lysed blood.
- Sequence and mapping of galectin-5, a beta-galactoside-binding lectin, found in rat erythrocytes.
- Isolation and expression of a gene encoding L-14-II, a new human soluble lactose-binding lectin.
- Apoptosis associated genes are induced in gerbil hippocampus following global ischemia.
- Neuronal injury produced by NMDA antagonists can be detected using heat shock proteins and can be blocked with antipsychotics.
- The stress gene response in brain.
- Patterns of cognitive recovery in sudden cardiac arrest survivors: the pilot study.
- Effects of transient global ischemia and kainate on poly(ADP-ribose) polymerase (PARP) gene expression and proteolytic cleavage in gerbil and rat brains.
- Acute neurologic and psychiatric complications associated with cocaine abuse.
- Endogenous muscle lectin inhibits myoblast adhesion to laminin.
- Heme oxygenase-1 (HO-1) protein induction in rat brain following focal ischemia.
- Pyrrolobenzodiazepines and related systems. 2. Synthesis and biological properties of isonoraptazepine derivatives.
- 5-Alkyl-2-(alkylthio)-6-(2,6-dihalophenylmethyl)-3, 4-dihydropyrimidin-4(3H)-ones: novel potent and selective dihydro-alkoxy-benzyl-oxopyrimidine derivatives.
- B Cell development and immunoglobulin gene transcription in the absence of Oct-2 and OBF-1.
- [[[(Thienylcarbonyl)alkyl]oxy]phenyl]- and [[[(pyrrylcarbonyl)alkyl]oxy]phenyl]oxazoline derivatives with potent and selective antihuman rhinovirus activity.
- Exploiting the plant secretory pathway to improve the anticancer activity of a plant-derived HPV16 E7 vaccine.
- Structure-based design, synthesis, and biological evaluation of conformationally restricted novel 2-alkylthio-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimi...
- 3-(4-aroyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides, a new class of synthetic histone deacetylase inhibitors.
- Structure-based design, synthesis, and biological evaluation of novel pyrrolyl aryl sulfones: HIV-1 non-nucleoside reverse transcriptase inhibitors active at nanomolar...
- Computer-assisted design, synthesis and biological evaluation of novel pyrrolyl heteroaryl sulfones targeted at HIV-1 reverse transcriptase as non-nucleoside inhibitors.
- [Heterocyclic systems. IV. Synthesis and CNS activity of derivatives of 4H,6H-pyrrolo[1,2-a][4,1]-benzoxazepine].
- Cloning and characterization of the hsp 18.55 gene, a new member of the small heat shock gene family isolated from wine Lactobacillus plantarum.
- Immunomodulatory activity of a plant extract containing human papillomavirus 16-E7 protein in human monocyte-derived dendritic Cells.
- L-29, an endogenous lectin, binds to glycoconjugate ligands with positive cooperativity.
- Structure-activity relationship studies on new DABOS: effect of substitutions at pyrimidine C-5 and C-6 positions on anti-HIV-1 activity.
- Synthesis and biological evaluation of 2-, 3-, and 4-acylaminocinnamyl-N-hydroxyamides as novel synthetic HDAC inhibitors.
- Beneficial effects of minocycline and botulinum toxin-induced constraint physical therapy following experimental traumatic brain injury.
- The BDNF Valine 68 to Methionine Polymorphism Increases Compulsive Alcohol Drinking in Mice That Is Reversed by Tropomyosin Receptor Kinase B Activation.
Conditions Treated
- Anterior Horn Disease
- Ataxia
- Carpal Tunnel Syndrome
- Convulsions
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Doctors Specialties
- Neurology
Accepted Insurances
Education
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UCSF -
University of Rochester School of Medicine and Dentistry
Hospital
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San Francisco VA Medical Center -
UCSF Medical Center
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