Charles S. Davidson Professor of Medicine, Mt. Auburn Hospital
Infectious Disease
Dr. Stephen Zinner, MD
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Dr. Stephen Zinner works in the field of Infectious Disease. He went to Perelman School of Medicine at the University of Pennsylvania. He received awards:"Elected Member". Doctor Stephen Zinner, MD is a published physician as well. He has 101 publications published. The latest was: Relevant aspects in the Infectious Diseases Society of America (IDSA) guidelines for the use of antimicrobial agents in neutropenic patients with unexplained fever.
Publications
- In Vitro Resistance Studies with Bacteria that Exhibit Low Mutation Frequencies: the Prediction of "Antimutant" Linezolid Concentrations Using a Mixed Inoculum Contain...
- Predicting bacterial resistance using the time inside the mutant selection window: Possibilities and limitations.
- Concentration-resistance relationships with Pseudomonas aeruginosa exposed to doripenem and ciprofloxacin in an in vitro model.
- [ICAAC (Interscience Conference on Antimicrobial Agents and Chemotherapy): the viewpoint of an American leader in Infectiology. Interview by E. Bergogne-Bérézin].
- The effects of sodium, chloride, and calcium concentration on the response of melanophores to melanocyte-stimulating hormone (MSH).
- Relevant aspects in the Infectious Diseases Society of America (IDSA) guidelines for the use of antimicrobial agents in neutropenic patients with unexplained fever.
- Factors associated with bacteraemia in febrile, granulocytopenic cancer patients. The International Antimicrobial Therapy Cooperative Group (IATCG) of the European Org...
- Opsonization of serum-sensitive and serum-resistant Escherichia coli by rough mutant (Re) antisera.
- New and unusual infections in neutropenic patients.
- Synergistic combinations of antibiotics in gram-negative bacillary infections.
- Serum inhibitory and bactericidal activity of ciprofloxacin following intravenous administration.
- Antistaphylococcal activity of rifampin with other antibiotics.
- Three antibiotic regimens in the treatment of infection in febrile granulocytopenic patients with cancer. The EORTC international antimicrobial therapy project group.
- Bacterial pathogens of increasing significance in hospital-acquired infections.
- Isolation of Eikenella corrodens in a general hospital.
- Efficacy of standard disc-diffusion test as applied to susceptibility of Staphylococcus aureus to tetracycline and minocycline.
- Synergism of trimethoprim combined with aminoglycosides in vitro and in serum of volunteers.
- Laboratory support for choosing and monitoring antimicrobial therapy in severely ill patients.
- Pharmacokinetics and bioavailability of intravenous-to-oral enoxacin in elderly patients with complicated urinary tract infections.
- Prospective randomized comparison of three antibiotic regimens for empirical therapy of suspected bacteremic infection in febrile granulocytopenic patients.
- Two compartment kinetic model with multiple artificial capillary units.
- Review of amikacin usage in the EORTC trials.
- Infection with Chlamydia trachomatis in female college students.
- Vaginal colonization with mycoplasma hominis and ureaplasma urealyticum.
- Stability of blood pressure rank and urinary kallikrein concentration in childhood: an eight-year follow-up.
- Vaginal colonization with group B streptococcus: a study in college women.
- Vaginal colonization with Corynebacterium vaginale (Haemophilus vaginalis).
- Chlamydia trachomatis in women: antibody in cervical secretions as a possible indicator of genital infection.
- Familial aggregation of urinary kallikrein concentration in childhood: relation to blood pressure, race and urinary electrolytes.
- Studies on the origin of human hypertension.
- Sexually transmitted conditions among women college students.
- A longitudinal study of blood pressure in childhood.
- Prophylaxis of bacterial infections with oral antibiotics in neutropenic patients. Lessons from the last two EORTC trials and prospects for the future.
- Single daily dosing of amikacin in an in-vitro model.
- An artificial capillary in vitro kinetic model of antibiotic bactericidal activity.
- Synergistic activity of trimethoprim and amikacin against gram-negative bacilli.
- In vitro models for the study of antibiotic activities.
- Piperacillin-tazobactam plus amikacin versus ceftazidime plus amikacin as empiric therapy for fever in granulocytopenic patients with cancer. The International Antimic...
- Monotherapy with meropenem versus combination therapy with ceftazidime plus amikacin as empiric therapy for fever in granulocytopenic patients with cancer. The Interna...
- In vitro models in the study of antibiotic therapy of infections in neutropenic patients.
- In vitro models for the study of combination antibiotic therapy in neutropenic patients.
- Effect of clindamycin on the in vitro activity of amikacin and gentamicin against gram-negative bacilli.
- Effect of mixing on rifampin bactericidal activity against staphylococci.
- In vitro antimicrobial activity of moxifloxacin against bacterial strains isolated from blood of neutropenic cancer patients.
- In-vitro activity of aztreonam in combination with four other antibiotics against gram-negative bacilli and Staphylococcus aureus.
- Blood pressure in infancy.
- Factors affecting blood pressures in newborn infants.
- Significance of blood pressure in infancy. Familial aggregation and predictive effect on later blood pressure.
- The antistaphylococcal pharmacodynamics of linezolid alone and in combination with doxycycline in an in vitro dynamic model.
- Maternal prenatal dietary potassium, calcium, magnesium, and infant blood pressure.
- Vancomycin versus placebo for treating persistent fever in patients with neutropenic cancer receiving piperacillin-tazobactam monotherapy.
- Prospective randomized evaluation of ciprofloxacin versus piperacillin plus amikacin for empiric antibiotic therapy of febrile granulocytopenic cancer patients with ly...
- Effect of dose on serum pharmacokinetics of intravenous ciprofloxacin with identification and characterization of extravascular compartments using noncompartmental and...
- Serum bactericidal activity of moxalactam and cefotaxime with and without tobramycin against Pseudomonas aeruginosa and Staphylococcus aureus.
- Efficacy of intermittent versus continuous administration of netilmicin in a two-compartment in vitro model.
- Cefotaxime and amikacin: results of in vitro and in vivo studies against Gram-negative bacteria and Staphylococcus aureus. EORTC International Antimicrobial Therapy Pr...
- Enhancement of leucocyte killing of resistant bacteria selected during exposure to aminoglycosides or quinolones.
- Use of an in-vitro kinetic model to study antibiotic combinations.
- In vitro and in vivo studies of three antibiotic combinations against gram-negative bacteria and Staphylococcus aureus.
- Comparison of tube dilution and microtitre methods for the detection of antibiotic tolerance in strains of Staphylococcus aureus.
- In-vitro studies of antibiotic combinations with special emphasis on the evaluation of newly developed methods.
- Impact of netilmicin regimens on the activities of ceftazidime-netilmicin combinations against Pseudomonas aeruginosa in an in vitro pharmacokinetic model.
- Bactericidal activity of ciprofloxacin alone and in combination with azlocillin in an in-vitro capillary model.
- Comparative study with enoxacin and netilmicin in a pharmacodynamic model to determine importance of ratio of antibiotic peak concentration to MIC for bactericidal act...
- Effect of dose and schedule on cefoperazone pharmacodynamics in an in vitro model of infection in a neutropenic host.
- New pathogens in neutropenic patients with cancer: an update for the new millennium.
- Pharmacokinetics and pharmacodynamics of intravenous ciprofloxacin. Studies in vivo and in an in vitro dynamic model.
- Combination therapy with ciprofloxacin plus azlocillin against Pseudomonas aeruginosa: effect of simultaneous versus staggered administration in an in vitro model of i...
- Predictors of effect of ampicillin-sulbactam against TEM-1 beta-lactamase-producing Escherichia coli in an in vitro dynamic model: enzyme activity versus MIC.
- Simulated in vitro quinolone pharmacodynamics at clinically achievable AUC/MIC ratios: advantage of I E over other integral parameters.
- Changing epidemiology of infections in patients with neutropenia and cancer: emphasis on gram-positive and resistant bacteria.
- Significance of "extravascular" protein binding for antimicrobial pharmacodynamics in an in vitro capillary model of infection.
- Pharmacodynamics of piperacillin alone and in combination with tazobactam against piperacillin-resistant and -susceptible organisms in an in vitro model of infection.
- Net effect of inoculum size on antimicrobial action of ampicillin-sulbactam: studies using an in vitro dynamic model.
- Activity of trovafloxacin (with or without ampicillin-sulbactam) against enterococci in an in vitro dynamic model of infection.
- Influence of medium and method on the in vitro susceptibility of Pseudomonas aeruginosa and other bacteria to ciprofloxacin and enoxacin.
- In vitro dynamic model for determining the comparative pharmacology of fluoroquinolones.
- Comparative pharmacodynamics of gatifloxacin and ciprofloxacin in an in vitro dynamic model: prediction of equiefficient doses and the breakpoints of the area under th...
- Comparative anti-staphylococcal effects of gemifloxacin and trovafloxacin in an in vitro dynamic model in terms of AUC/MIC and dose relationships.
- Dose ranging and fractionation of intravenous ciprofloxacin against Pseudomonas aeruginosa and Staphylococcus aureus in an in vitro model of infection.
- Prediction of the antimicrobial effects of trovafloxacin and ciprofloxacin on staphylococci using an in-vitro dynamic model.
- Prediction of the effects of inoculum size on the antimicrobial action of trovafloxacin and ciprofloxacin against Staphylococcus aureus and Escherichia coli in an in v...
- MIC-based interspecies prediction of the antimicrobial effects of ciprofloxacin on bacteria of different susceptibilities in an in vitro dynamic model.
- A new approach to in vitro comparisons of antibiotics in dynamic models: equivalent area under the curve/MIC breakpoints and equiefficient doses of trovafloxacin and c...
- Inter- and intraquinolone predictors of antimicrobial effect in an in vitro dynamic model: new insight into a widely used concept.
- Relationships of the area under the curve/MIC ratio to different integral endpoints of the antimicrobial effect: gemifloxacin pharmacodynamics in an in vitro dynamic m...
- Gemifloxacin and ciprofloxacin pharmacodynamics in an in-vitro dynamic model: prediction of the equivalent AUC/MIC breakpoints and doses.
- Comparative pharmacodynamics of moxifloxacin and levofloxacin in an in vitro dynamic model: prediction of the equivalent AUC/MIC breakpoints and equiefficient doses.
- Comparative activities of ciprofloxacin and levofloxacin against Streptococcus pneumoniae in an In vitro dynamic model.
- The pharmacodynamics of gatifloxacin and ciprofloxacin for pneumococci in an in vitro dynamic model: prediction of equiefficient doses.
- Comparative Pharmacodynamics and Antimutant Potentials of Doripenem and Imipenem with Ciprofloxacin-Resistant Pseudomonas aeruginosa in an In Vitro Model.
- Emergence of resistant Streptococcus pneumoniae in an in vitro dynamic model that simulates moxifloxacin concentrations inside and outside the mutant selection window:...
- In vitro pharmacodynamic evaluation of the mutant selection window hypothesis using four fluoroquinolones against Staphylococcus aureus.
- The impact of duration of antibiotic exposure on bacterial resistance predictions using in vitro dynamic models.
- Linezolid pharmacodynamics with Staphylococcus aureus in an in vitro dynamic model.
- Enrichment of resistant Staphylococcus aureus at ciprofloxacin concentrations simulated within the mutant selection window: bolus versus continuous infusion.
- Telavancin and vancomycin pharmacodynamics with Staphylococcus aureus in an in vitro dynamic model.
- Enrichment of fluoroquinolone-resistant Staphylococcus aureus: oscillating ciprofloxacin concentrations simulated at the upper and lower portions of the mutant selecti...
- Selection of linezolid-resistant Enterococcus faecium in an in vitro dynamic model: protective effect of doxycycline.
- Antibiotic use: present and future.
Schools
Perelman School of Medicine University of Pennsylvania
University Chicago Hosps
Boston City Hospital
Doctors Specialties
- Infectious Disease Medicine
- Infectious Disease
Accepted Insurances
Awards
- Elected Member
Education
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Boston University Medical Center -
University of Chicago -
Perelman School of Medicine at the University of Pennsylvania
Hospital
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Mount Auburn Hospital
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