Professor, Pathology and Immunology, Washington University School of Medicine
Pathology
Jacques U. Baenziger
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Jacques Baenziger is an expert in the field of Pathology. Jacques Baenziger is also published. He has 101 publications published. The lastest publication: "Induction of cytotoxic T lymphocytes by intramuscular immunization with plasmid DNA is facilitated by bone marrow-derived cells.'
Publications
- Not so sweet malignant transformation.
- Modulation of Mannose- and Asialoglycoprotein-receptor expression determines glycoprotein hormone half-life at critical points in the reproductive cycle.
- O-mannosylation of cadherins.
- Loss of dermatan-4-sulfotransferase 1 (D4ST1/CHST14) function represents the first dermatan sulfate biosynthesis defect, "dermatan sulfate-deficient adducted thumb-clu...
- Loss of dermatan-4-sulfotransferase 1 function results in adducted thumb-clubfoot syndrome.
- The asialoglycoprotein receptor regulates levels of plasma glycoproteins terminating with sialic acid alpha2,6-galactose.
- Ablation of GalNAc-4-sulfotransferase-1 enhances reproduction by altering the carbohydrate structures of luteinizing hormone in mice.
- A necessary and sufficient determinant for protein-selective glycosylation in vivo.
- N-linked oligosaccharides on the low density lipoprotein receptor homolog SorLA/LR11 are modified with terminal GalNAc-4-SO4 in kidney and brain.
- The asialoglycoprotein receptor clears glycoconjugates terminating with sialic acid alpha 2,6GalNAc.
- Closely related mammals have distinct asialoglycoprotein receptor carbohydrate specificities.
- Neuronal-specific synthesis and glycosylation of tenascin-R.
- A major step on the road to understanding a unique posttranslational modification and its role in a genetic disease.
- Rapid clearance of sialylated glycoproteins by the asialoglycoprotein receptor.
- The Man/GalNAc-4-SO4-receptor: relating specificity to function.
- Spatial and temporal regulation of tenascin-R glycosylation in the cerebellum.
- Molecular cloning and characterization of chondroitin-4-O-sulfotransferase-3. A novel member of the HNK-1 family of sulfotransferases.
- Regulation of lutropin circulatory half-life by the mannose/N-acetylgalactosamine-4-SO4 receptor is critical for implantation in vivo.
- Induction of cytotoxic T lymphocytes by intramuscular immunization with plasmid DNA is facilitated by bone marrow-derived cells.
- Effect of rabbit anti-asialo GM1 treatment in vivo or with anti-asialo GM1 plus complement in vitro on cytotoxic T cell activities.
- Deuterium NMR as a monitor of organization and dynamics at the surface of membranes: the glycolipids.
- Induction or prevention of immunopathological disease by cloned cytotoxic T cell lines specific for lymphocytic choriomeningitis virus.
- Clinical, immunologic, and virologic observations related to human immunodeficiency virus (HIV) type 1 infection in a volunteer in an HIV-1 vaccine clinical trial.
- Lack of association between anti-V3 loop antibodies and perinatal transmission of HIV-1 in Kampala, Uganda.
- Relationship between platelet monoamine oxidase B activity and alleles at the MAOB locus.
- Characterization of virus-specific cytotoxic T cell clones from allogeneic bone marrow chimeras.
- Nonenzymatic glycosylation of low density lipoproteins in vitro. Effects on cell-interactive properties.
- Bispecific antibodies that mediate killing of cells infected with human immunodeficiency virus of any strain.
- Molecular analysis of the antigen receptor of virus-specific cytotoxic T cells and identification of a new V alpha family.
- The structure of the glycopeptide of human gamma G myeloma proteins.
- Structure of an antifreeze polypeptide and its precursor from the ocean pout, Macrozoarces americanus.
- Structure of the carbohydrate units of IgA1 immunoglobulin. I. Composition, glycopeptide isolation, and structure of the asparagine-linked oligosaccharide units.
- Deficient uridine diphosphate-N-acetylglucosamine:glycoprotein N-acetylglucosaminyltransferase activity in a clone of Chinese hamster ovary cells with altered surface ...
- Structure of the carbohydrate units of IgA1 immunoglobulin. II. Structure of the O-glycosidically linked oligosaccharide units.
- Structure of the carbohydrate units of IgE immunoglobulin. II. Sequence of the sialic acid-containing glycopeptides.
- Structure of the carbohydrate units of IgE immunoglobulin. I. Over-all composition, glycopeptide isolation, and structure of the high mannose oligosaccharide unit.
- Metabolic labeling of lutropin with [35S]sulfate.
- GLUT-4 NH2 terminus contains a phenylalanine-based targeting motif that regulates intracellular sequestration.
- Human platelet-derived growth factor. Purification and resolution into two active protein fractions.
- Oligosaccharide specific endocytosis by isolated rat hepatic reticuloendothelial cells.
- Rapid separation of anionic oligosaccharide species by high performance liquid chromatography.
- Photoactivatable glycopeptide reagents for site-specific labeling of lectins.
- Structural studies of the phosphorylated high mannose-type oligosaccharides on human beta-glucuronidase.
- Characterization of a mannose and N-acetylglucosamine-specific lectin present in rat hepatocytes.
- Isolation and structural characterization of the polypeptide subunits of membrane glycoprotein IIb-IIIa from human platelets.
- Structural studies of the endoglycosidase H-resistant oligosaccharides present on human beta-glucuronidase.
- Synthesis, processing, and secretion of the core-specific lectin by rat hepatocytes and hepatoma cells.
- Preparation of glycopeptide and oligosaccharide probes for receptor studies.
- Size fractionation of anionic oligosaccharides and glycopeptides by high-performance liquid chromatography.
- Structures of the O-glycosidically linked oligosaccharides of human IgD.
- Structures of the oligosaccharides present at the three asparagine-linked glycosylation sites of human IgD.
- Sulfation of lutropin oligosaccharides with a cell-free system.
- Recognition and receptor-mediated uptake of phosphorylated high mannose-type oligosaccharides by cultured human fibroblasts.
- Recycling of the hepatocyte asialoglycoprotein receptor does not require delivery of ligand to lysosomes.
- Evidence for transmembrane modulation of the ligand-binding site of the hepatocyte galactose/N-acetylgalactosamine-specific receptor.
- The role of glycosylation in protein recognition. Warner-Lambert Parke-Davis Award lecture.
- Cell-free sulfation of human and bovine pituitary hormones. Comparison of the sulfated oligosaccharides of lutropin, follitropin, and thyrotropin.
- Structural requirements for sulfation of asparagine-linked oligosaccharides of lutropin.
- Biosynthesis and secretion of the rat core-specific lectin. Relationship of post-translational modification and assembly to attainment of carbohydrate binding activity.
- Separation of anionic oligosaccharides by high-performance liquid chromatography.
- Intracellular transport and processing of secretory component in cultured rat hepatocytes.
- Lectin affinity high-performance liquid chromatography. Interactions of N-glycanase-released oligosaccharides with Ricinus communis agglutinin I and Ricinus communis a...
- Oligosaccharide specificities of Phaseolus vulgaris leukoagglutinating and erythroagglutinating phytohemagglutinins. Interactions with N-glycanase-released oligosaccha...
- Identification of the post-translational modifications of the core-specific lectin. The core-specific lectin contains hydroxyproline, hydroxylysine, and glucosylgalact...
- Isolation and characterization of the receptor on human neutrophils that mediates cellular adherence.
- Lectin affinity high-performance liquid chromatography: interactions of N-glycanase-released oligosaccharides with leukoagglutinating phytohemagglutinin, concanavalin ...
- Cleavage of membrane secretory component to soluble secretory component occurs on the cell surface of rat hepatocyte monolayers.
- Purification and characterization of the core-specific lectin from human serum and liver.
- Pituitary glycoprotein hormone oligosaccharides: structure, synthesis and function of the asparagine-linked oligosaccharides on lutropin, follitropin and thyrotropin.
- Asparagine-linked oligosaccharides on lutropin, follitropin, and thyrotropin. II. Distributions of sulfated and sialylated oligosaccharides on bovine, ovine, and human...
- Asparagine-linked oligosaccharides on lutropin, follitropin, and thyrotropin. I. Structural elucidation of the sulfated and sialylated oligosaccharides on bovine, ovin...
- Post-translational modifications of the core-specific lectin. Relationship to assembly, ligand binding, and secretion.
- Differential processing of Asn-linked oligosaccharides on pituitary glycoprotein hormones: implications for biologic function.
- In vivo and in vitro tyrosine sulfation of a membrane glycoprotein.
- Proteolytic processing of rat liver membrane secretory component. Cleavage activity is localized to bile canalicular membranes.
- Sulphation of proteins secreted by a human hepatoma-derived cell line. Sulphation of N-linked oligosaccharides on alpha 2HS-glycoprotein.
- Separation of two populations of endocytic vesicles involved in receptor-ligand sorting in rat hepatocytes.
- Structural elucidation of the disulfated oligosaccharide from bovine lutropin.
- The asparagine-linked oligosaccharides on bovine fetuin. Structural analysis of N-glycanase-released oligosaccharides by 500-megahertz 1H NMR spectroscopy.
- A pituitary N-acetylgalactosamine transferase that specifically recognizes glycoprotein hormones.
- The sialylated oligosaccharides of recombinant bovine lutropin modulate hormone bioactivity.
- Recognition by the glycoprotein hormone-specific N-acetylgalactosaminetransferase is independent of hormone native conformation.
- The minor components of the rat asialoglycoprotein receptor are apically located in neonatal enterocytes.
- Characterization of a sulfotransferase responsible for the 4-O-sulfation of terminal beta-N-acetyl-D-galactosamine on asparagine-linked oligosaccharides of glycoprotei...
- A microplate assay for analysis of solution-phase glycosyltransferase reactions: determination of kinetic constants.
- Circulatory half-life but not interaction with the lutropin/chorionic gonadotropin receptor is modulated by sulfation of bovine lutropin oligosaccharides.
- Wheat germ agglutinin is selectively transported to multivesicular bodies.
- Ligand-specific isolation of endosomes and lysosomes using superparamagnetic colloidal iron dextran glycoconjugates and high gradient magnetic affinity chromatography.
- A hepatic reticuloendothelial cell receptor specific for SO4-4GalNAc beta 1,4GlcNAc beta 1,2Man alpha that mediates rapid clearance of lutropin.
- Pro-opiomelanocortin synthesized by corticotrophs bears asparagine-linked oligosaccharides terminating with SO4-4GalNAc beta 1,4GlcNAc beta 1,2Man alpha.
- The asparagine-linked oligosaccharides on tissue factor pathway inhibitor terminate with SO4-4GalNAc beta 1, 4GlcNAc beta 1,2 Mana alpha.
- Differential sorting of lutropin and the free alpha-subunit in cultured bovine pituitary cells.
- Abnormal surface distribution of the human asialoglycoprotein receptor in cirrhosis.
- Molecular basis of recognition by the glycoprotein hormone-specific N-acetylgalactosamine-transferase.
- Structural determinants of Ricinus communis agglutinin and toxin specificity for oligosaccharides.
- Structure of the oligosaccharide of human J chain.
- Structural determinants of concanavalin A specificity for oligosaccharides.
- Structure of the complex oligosaccharides of fetuin.
- Oligosaccharides containing beta 1,4-linked N-acetylgalactosamine, a paradigm for protein-specific glycosylation.
- Glycosylation: to what end for the glycoprotein hormones?
Schools
Washington Center School of Medicine
Doctors Specialties
- Pathology
Accepted Insurances
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