Associate Professor, Internal Medicine, Washington University in St. Louis School of Medicine
Pathology
Jason C. Mills
Jason C. Mills practices Pathology. He went to medical school at Perelman School of Medicine at the University of Pennsylvania. He over the years received 1 awards: "Elected Member". Jason C. Mills is a published physician as well. He has 48 publications published. The latest was: Identification of Alanyl Aminopeptidase (CD13) as a Surface Marker for Isolation of Mature Gastric Zymogenic Chief Cells.
Publications
- Identification of Alanyl Aminopeptidase (CD13) as a Surface Marker for Isolation of Mature Gastric Zymogenic Chief Cells.
- Establishment of novel in vitro mouse chief cell and SPEM cultures identifies MAL2 as a marker of metaplasia in the stomach.
- RAB26 coordinates lysosome traffic and mitochondrial localization.
- Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium.
- Evolution of the Human Gastrokine Locus and Confounding Factors Regarding the Pseudogenicity of Gkn3.
- Autoimmune Gastritis Mediated by CD4+ T Cells Promotes the Development of Gastric Cancer.
- The hyaluronic acid receptor CD44 coordinates normal and metaplastic gastric epithelial progenitor cell proliferation.
- Helicobacter pylori promotes the expression of krüppel-like factor 5, a mediator of carcinogenesis, in vitro and in vivo.
- Protamine sulfate induced bladder injury protects from distention induced bladder pain.
- Scaling factors: Transcription factors regulating subcellular domains.
- Tamoxifen induces rapid, reversible atrophy and metaplasia in mouse stomach.
- The origin of pre-neoplastic metaplasia in the stomach: Chief cells emerge from the Mist.
- Transcription factor MIST1 in terminal differentiation of mouse and human plasma cells.
- Gastric epithelial stem cells.
- XBP1 controls maturation of gastric zymogenic cells by induction of MIST1 and expansion of the rough endoplasmic reticulum.
- Mature chief cells are cryptic progenitors for metaplasia in the stomach.
- The transcription factor MIST1 is a novel human gastric chief cell marker whose expression is lost in metaplasia, dysplasia, and carcinoma.
- Inducible activation of Cre recombinase in adult mice causes gastric epithelial atrophy, metaplasia, and regenerative changes in the absence of "floxed" alleles.
- Spasmolytic polypeptide-expressing metaplasia and intestinal metaplasia: time for reevaluation of metaplasias and the origins of gastric cancer.
- RAB26 and RAB3D are direct transcriptional targets of MIST1 that regulate exocrine granule maturation.
- Helicobacter pylori immune escape is mediated by dendritic cell-induced Treg skewing and Th17 suppression in mice.
- Mucoepidermoid carcinoma of the cervix: another tumor with the t(11;19)-associated CRTC1-MAML2 gene fusion.
- Bone morphogenetic protein 4 signaling regulates epithelial renewal in the urinary tract in response to uropathogenic infection.
- Regulation of mouse embryonic stem cell neural differentiation by retinoic acid.
- How form follows functional genomics: gene expression profiling gastric epithelial cells with a particular discourse on the parietal cell.
- The gastric epithelial progenitor cell niche and differentiation of the zymogenic (chief) cell lineage.
- IFN-gamma-dependent regulatory circuits in immune inflammation highlighted in diabetes.
- Diverse adult stem cells share specific higher-order patterns of gene expression.
- Minimum information specification for in situ hybridization and immunohistochemistry experiments (MISFISHIE).
- A molecular signature of gastric metaplasia arising in response to acute parietal cell loss.
- Matrix metalloproteinases expressed by astrocytes mediate extracellular amyloid-beta peptide catabolism.
- Molecular properties of adult mouse gastric and intestinal epithelial progenitors in their niches.
- Development of the Minimum Information Specification for In Situ Hybridization and Immunohistochemistry Experiments (MISFISHIE).
- Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury.
- A transgenic mouse model of metastatic carcinoma involving transdifferentiation of a gastric epithelial lineage progenitor to a neuroendocrine phenotype.
- Molecular characterization of mouse gastric zymogenic cells.
- The impact of parietal cells on Helicobacter pylori tropism and host pathology: an analysis using gnotobiotic normal and transgenic mice.
- Molecular features of adult mouse small intestinal epithelial progenitors.
- Molecular characterization of mouse gastric epithelial progenitor cells.
- Vav proteins are necessary for correct differentiation of mouse cecal and colonic enterocytes.
- The gastric mucosa development and differentiation.
- Geminin cooperates with Polycomb to restrain multi-lineage commitment in the early embryo.
- A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity.
- The maturation of mucus-secreting gastric epithelial progenitors into digestive-enzyme secreting zymogenic cells requires Mist1.
- GATA2 functions at multiple steps in hemangioblast development and differentiation.
- GOurmet: a tool for quantitative comparison and visualization of gene expression profiles based on gene ontology (GO) distributions.
- Location, allocation, relocation: isolating adult tissue stem cells in three dimensions.
Schools
Perelman School of Medicine University of Pennsylvania
Doctors Specialties
- Pathology
Accepted Insurances
Awards
- Elected Member
Education
-
Perelman School of Medicine at the University of Pennsylvania
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