Clinical Fellow in Pediatrics, Boston Children's Hospital
Pediatric Gastroenterology
Jay R. Thiagarajah, MB BS
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Jay R. Thiagarajah, MB BS practices Pediatric Gastroenterology. He studied medicine at St. George's Hospital Medical School. Jay R. Thiagarajah, MB BS is also published. He has 16 publications published. The lastest publication: "Microbial sphingomyelinase induces RhoA-mediated reorganization of the apical brush border membrane and is protective against invasion.'
Publications
- Microbial sphingomyelinase induces RhoA-mediated reorganization of the apical brush border membrane and is protective against invasion.
- Discovery and development of antisecretory drugs for treating diarrheal diseases.
- Chloride channel inhibition by a red wine extract and a synthetic small molecule prevents rotaviral secretory diarrhoea in neonatal mice.
- Chloride channel-targeted therapy for secretory diarrheas.
- Response to "Diffusion versus convection".
- Convective washout reduces the antidiarrheal efficacy of enterocyte surface-targeted antisecretory drugs.
- CFTR Inhibitors.
- Inhibition of Ca2+-activated Cl- channels by gallotannins as a possible molecular basis for health benefits of red wine and green tea.
- Airway surface liquid depth imaged by surface laser reflectance microscopy.
- Impaired enterocyte proliferation in aquaporin-3 deficiency in mouse models of colitis.
- Slowed diffusion in tumors revealed by microfiberoptic epifluorescence photobleaching.
- Noninvasive early detection of brain edema in mice by near-infrared light scattering.
- New drug targets for cholera therapy.
- Submucosal gland dysfunction as a primary defect in cystic fibrosis.
- Altered goblet cell differentiation and surface mucus properties in hirschsprung disease.
Doctors Specialties
- Pediatric Gastroenterology
Accepted Insurances
Education
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Boston Children's Hospital -
Massachusetts General Hospital -
St. George's Hospital Medical School
Hospital
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Boston Children's Hospital
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