Associate Professor, Laboratory Medicine, University of Washington School of Medicine
Pathology
Dr. David R. Gretch, MD
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Dr. David R. Gretch works in the field of Pathology. He graduated from University of Iowa Carver College of Medicine. University of Iowa Carver College of Medicine is ranked 29 in research and 16 in primary care medicine David R. Gretch, MD is a published doctor as well. He has 34 publications published. The latest was: Fibrosing Cholestatic Hepatitis C After Hematopoietic Cell Transplantation: Report of 3 Fatal Cases.
Publications
- Fibrosing Cholestatic Hepatitis C After Hematopoietic Cell Transplantation: Report of 3 Fatal Cases.
- Advocating the Concept of GBV Biotherapy Against AIDS.
- Genetic and functional heterogeneity of the hepatitis C virus p7 ion channel during natural chronic infection.
- Genetic Diversity of Near Genome-Wide Hepatitis C Virus Sequences during Chronic Infection: Evidence for Protein Structural Conservation Over Time.
- Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity.
- Genetic diversity of hepatitis C virus predicts recurrent disease after liver transplantation.
- Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells.
- Interpretation of positive transcription-mediated amplification test results from polymerase chain reaction-negative samples obtained after treatment of chronic hepati...
- Investigation of putative multisubtype hepatitis C virus infections in vivo by heteroduplex mobility analysis of core/envelope subgenomes.
- Hepatitis C virus envelope glycoprotein co-evolutionary dynamics during chronic hepatitis C.
- Preservation of intrahepatic hepatitis C virus (HCV)-specific CD4+ T cell responses despite global loss of CD4+ T cells in HCV/HIV coinfection.
- Hepatitis C virus dynamics during natural infection are associated with long-term histological outcome of chronic hepatitis C disease.
- Molecular diagnostics of hepatitis C virus infection: a systematic review.
- Hepatitis C virus replication in transfected and serum-infected cultured human fetal hepatocytes.
- Impact of reducing peginterferon alfa-2a and ribavirin dose during retreatment in patients with chronic hepatitis C.
- Social structural and behavioral underpinnings of hyperendemic hepatitis C virus transmission in drug injectors.
- Identification of a specific gene expression pattern associated with HCV-induced pathogenesis in HCV- and HCV/HIV-infected individuals.
- HIV infection and antiretroviral therapy: effect on hepatitis C virus quasispecies variability.
- High rate of spontaneous negativity for hepatitis C virus RNA after establishment of chronic infection in Alaska Natives.
- Productive replication of hepatitis C virus in perihepatic lymph nodes in vivo: implications of HCV lymphotropism.
- High serum hepatitis C virus (HCV) RNA load predicts the presence of HCV RNA in saliva from individuals with chronic and acute HCV infection.
- Intrahepatic hepatitis C virus replication correlates with chronic hepatitis C disease severity in vivo.
- Decreased NK cell frequency in chronic hepatitis C does not affect ex vivo cytolytic killing.
- Estimating the date of hepatitis C virus infection from patient interviews and antibody tests on stored sera.
- Absence of antibodies to cyclic citrullinated peptide in sera of patients with hepatitis C virus infection and cryoglobulinemia.
- Effects of the hepatitis C virus core protein on innate cellular defense pathways.
- Epidemiology and risk factors for hepatitis C in Alaska Natives.
- Strengths and limitations of commercial tests for hepatitis C virus RNA quantification.
- Hepatitis C virus-specific cytolytic T cell responses after antiviral therapy.
- Dynamics of hepatitis C virus replication in human liver.
- Hepatitis C and alcohol: fundamental and translational research directions.
- Prevalence of hepatitis C virus infection and risk factors in an incarcerated juvenile population: a pilot study.
- Hepatitis C virus NS5A colocalizes with the core protein on lipid droplets and interacts with apolipoproteins.
Schools
University of Ia Roy J amp L Carver Com
University Wash Med Center
Doctors Specialties
- Clinical Pathology
- Pathology
Accepted Insurances
Education
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University of Iowa Carver College of Medicine
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