Professor of Medicine, University Wash
Oncology
Dr. Frederick R. Appelbaum, MD
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Frederick Appelbaum is an expert in the field of Oncology. He received awards:"Fellow (FASCO)". Frederick R. Appelbaum is also published. He has 101 publications published. The lastest publication: "Relationhip between event-free survival and overall survival in acute myeloid leukemia: A report from SWOG, HOVN/SAKK, and MRC/NCRI.'
Publications
- Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia: Time to Move Toward a Minimal Residual Disease-Based Definition of Complete Remission?
- Hematopoietic Cell Transplantation after Solid Organ Transplantation.
- Cytogenetic prioritization with inclusion of molecular markers predicts outcome in previously untreated patients with chronic lymphocytic Leukemia treated with fludara...
- Relation of Clinical Response and Minimal Residual Disease and Their Prognostic Impact on Outcome in Acute Myeloid Leukemia.
- Low Platelet count reduces subsequent complete remission rate despite marrow with <5% blasts after AML induction therapy.
- Resistance prediction in AML: analysis of 4601 patients from MRC/NCRI, HOVON/SAKK, SWOG and MD Anderson Cancer Center.
- Recommendations for donor human leukocyte antigen assessment and matching for allogeneic stem Cell transplantation: consensus opinion of the Blood and Marrow Transplan...
- G-CSF priming, clofarabine, and high dose cytarabine (GCLAC) for upfront treatment of Acute myeloid leukemia, advanced myelodysplastic syndrome or advanced myeloprolif...
- Blood and Marrow Transplant Clinical Trials Network State of the Science Symposium 2014.
- Number of Courses of Induction Therapy Independently Predicts Outcome after Allogeneic Transplantation for AML in First Morphological Remission.
- Value of Routine 'Day 14' Marrow Exam in Newly-Diagnosed AML.
- Comparison of minimal residual Disease as outcome predictor for AML patients in first complete remission undergoing myeloablative or nonmyeloablative allogeneic hemato...
- Multicenter Biologic Assignment Trial Comparing Reduced-Intensity Allogeneic Hematopoietic Cell Transplant to Hypomethylating Therapy or Best Supportive Care in Patien...
- Pre-transplant comorbidities predict severity of Acute graft-versus-host disease and subsequent mortality.
- Prognostic factors and outcomes of severe gastrointestinal GVHD after allogeneic hematopoietic Cell transplantation.
- Heterogeneity of clonal expansion and maturation-linked mutation acquisition in hematopoietic progenitors in human Acute myeloid leukemia.
- Declining rates of treatment-related mortality in patients with newly diagnosed AML given 'intense' induction regimens: a report from SWOG and MD Anderson.
- Myeloablative I-131-ToSitumomab with Escalating Doses of Fludarabine and Autologous Hematopoietic Transplantation for Adults Age ≥ 60 Years with B Cell Lymphoma.
- Treosulfan, Fludarabine, and 2-Gy Total Body Irradiation Followed by Allogeneic Hematopoietic Cell Transplantation in Patients with Myelodysplastic Syndrome and Acute ...
- Risk assessment before allogeneic hematopoietic cell transplantation for older adults with Acute myeloid leukemia.
- Acute Myeloid Leukemia, Version 2.2013.
- The NCI common toxicity criteria and treatment-associated mortality in Acute myeloid leukemia.
- Implementing a Death with Dignity program at a comprehensive Cancer center.
- The impact of initial fludarabine therapy on transformation to Richter syndrome or prolymphocytic Leukemia in patients with chronic lymphocytic Leukemia: analysis of a...
- Impact of age on outcomes after initial therapy with chemotherapy and different chemoimmunotherapy regimens in patients with chronic lymphocytic Leukemia: results of s...
- Who is the better donor for older hematopoietic transplant recipients: an older-aged sibling or a young, matched unrelated volunteer?
- Retrospective comparison of clofarabine versus fludarabine in combination with high-dose cytarabine with or without granulocyte colony-stimulating factor as salvage th...
- Improved outcomes with allogeneic hematopoietic Cell transplantation.
- Retrospective. E. Donnall Thomas (1920-2012).
- To transplant or not to transplant for adult Acute myeloid leukemia: an ever-evolving decision.
- Prognostic and therapeutic implications of minimal residual disease at the time of transplantation in Acute leukemia.
- Mutations in the DNMT3A exon 23 independently predict poor outcome in older patients with Acute myeloid leukemia: a SWOG report.
- Haematological Cancer: The rule of three in AML induction-is cladribine the answer?
- Success of allogeneic marrow transplantation for children with severe aplastic anaemia.
- Pre-Transplant Therapy with Azacitidine Versus Induction Chemotherapy and Post-Transplant Outcome in Patients with MDS.
- The Dynamic International Prognostic Scoring System for myelofibrosis predicts outcomes after hematopoietic Cell transplantation.
- Anti-T Cell antibodies as part of the preparative regimen in hematopoietic Cell transplantation-a debate.
- Phase 2 trial of vorinostat and gemtuzumab ozogamicin as induction and post-remission therapy in older adults with previously untreated Acute myeloid leukemia.
- Prediction of early death after induction therapy for newly diagnosed Acute myeloid leukemia with pretreatment risk scores: a novel paradigm for treatment assignment.
- Prognostic impact of discordant results from cytogenetics and flow cytometry in patients with Acute myeloid leukemia undergoing hematopoietic cell transplantation.
- Impact of residual normal metaphases in core binding factor Acute myeloid leukemia.
- Prognostic implications of the IDH1 synonymous SNP rs11554137 in pediatric/adult AML: a report from the Children's Oncology Group and SWOG.
- Clofarabine with high dose cytarabine and granulocyte colony-stimulating factor (G-CSF) priming for relapsed and refractory Acute myeloid leukaemia.
- Preparative Regimens and Ageism.
- Incidence of Therapy-related Myeloid Neoplasia after Initial Therapy for CLL with Fludarabine-Cyclophosphamide versus Fludarabine: Long-Term Follow-up of US Intergroup...
- Indications for and current results with allogeneic hematopoietic Cell transplantation in patients with myelofibrosis.
- Outcome of Acute myeloid leukemia patients with monosomal karyotype who undergo hematopoietic cell transplantation.
- Infections in relapsed or refractory Acute myeloid leukemia patients given clofarabine+cytarabine.
- Cytarabine dose for Acute myeloid leukemia.
- Influence of immunosuppressive treatment on risk of recurrent malignancy after allogeneic hematopoietic Cell transplantation.
- Anti-CD45 pretargeted radioimmunotherapy using bismuth-213: high rates of complete remission and long-term survival in a mouse myeloid Leukemia xenograft model.
- A phase 2 study of lenalidomide monotherapy in patients with deletion 5q Acute myeloid leukemia: Southwest Oncology Group Study S0605.
- Impact of cranial irradiation added to intrathecal conditioning in hematopoietic cell transplantation in adult Acute myeloid leukemia with central nervous system invol...
- What pediatrics can teach us.
- A Retrospective Comparison of Tacrolimus versus Cyclosporine with Methotrexate for Immunosuppression after Allogeneic Hematopoietic Cell Transplantation with Mobilized...
- Impact of pretransplantation minimal residual Disease, as detected by multiparametric flow cytometry, on outcome of myeloablative hematopoietic cell transplantation fo...
- Comparative analysis of risk factors for Acute graft-versus-host disease and for chronic graft-versus-host disease according to National Institutes of Health consensus...
- Outpatient management following intensive induction chemotherapy for myelodysplastic syndromes and Acute myeloid leukemia: a pilot study.
- Conditioning with treosulfan and fludarabine followed by allogeneic hematopoietic Cell transplantation for high-risk hematologic malignancies.
- Generic immunosuppressants in hematopoietic Cell transplantation.
- Identifying older patients with Acute myeloid leukemia who may be candidates for reduced-intensity hematopoietic cell transplantation.
- Acute myeloid leukemia.
- A Phase I/II Study of Chemotherapy Followed by Donor Lymphocyte Infusion plus Interleukin-2 for Relapsed Acute Leukemia after Allogeneic Hematopoietic Cell Transplanta...
- Allogeneic Hematopoietic Cell Transplantation with Full-Intensity Conditioning for Adult Acute Lymphoblastic Leukemia: Results from a Single Center, 1998-2006.
- Does microgranular variant morphology of Acute promyelocytic leukemia independently predict a less favorable outcome compared with classical M3 APL? A joint study of t...
- Reduced mortality after allogeneic hematopoietic-Cell transplantation.
- Allogeneic hematopoietic Cell transplantation for hematologic malignancy: relative risks and benefits of double umbilical cord blood.
- Arsenic trioxide improves event-free and overall survival for adults with Acute promyelocytic leukemia: North American Leukemia Intergroup Study C9710.
- Shortcomings in the clinical evaluation of new drugs: Acute myeloid leukemia as paradigm.
- Allogeneic Hematopoietic Cell Transplantation for Chronic Myelomonocytic Leukemia: Relapse-Free Survival is Determined by Karyotype and Comorbidities.
- Impact of recipient statin treatment on Graft-versus-host disease after allogeneic hematopoietic cell transplantation.
- Prognostic impact of monosomal karyotype in young adult and elderly Acute myeloid leukemia: the Southwest Oncology Group (SWOG) experience.
- Nonmyeloablative allogeneic hematopoietic cell transplantation in patients with Acute myeloid leukemia.
- Therapy of relapsed Leukemia after allogeneic hematopoietic cell transplantation with T cells specific for minor histocompatibility antigens.
- Effect of complete remission and responses less than complete remission on survival in Acute myeloid leukemia: a combined Eastern Cooperative Oncology Group, Southwest...
- Life expectancy in patients surviving more than 5 years after hematopoietic Cell transplantation.
- Donor statin treatment protects against severe Acute graft-versus-host disease after related allogeneic hematopoietic cell transplantation.
- Allogeneic hematopoietic Cell transplantation after conditioning with 131I-anti-CD45 antibody plus fludarabine and low-dose total body irradiation for elderly patients...
- Low relapse without excessive transplant-related mortality following myeloablative cord blood transplantation for Acute leukemia in complete remission: a matched cohor...
- Structural and functional alterations of FLT3 in Acute myeloid leukemia.
- Allogeneic stem cell transplantation for Acute myeloid leukemia in first complete remission: systematic review and meta-analysis of prospective clinical trials.
- Longitudinal assessment of morbidity and Acute graft-versus-host disease after allogeneic hematopoietic cell transplantation: retrospective analysis of a multicenter p...
- Long-term outcome of patients with multiple myeloma after autologous hematopoietic cell transplantation and nonmyeloablative alloGrafting.
- Initial therapy of Acute graft-versus-host disease with low-dose prednisone does not compromise patient outcomes.
- Very late antigen-4 function of myeloblasts correlates with improved overall survival for patients with Acute myeloid leukemia.
- Thyroid function following hematopoietic Cell transplantation in children: 30 years' experience.
- Pretargeted radioimmunotherapy using anti-CD45 monoclonal antibodies to deliver radiation to murine hematolymphoid tissues and human myeloid Leukemia.
- Generation of HIV-1-specific CD8+ Cell responses following allogeneic hematopoietic Cell transplantation.
- Pretransplant neutropenia is associated with poor-risk cytogenetic features and increased infection-related mortality in patients with Myelodysplastic syndromes.
- Hematopoietic cell transplantation for non-Hodgkin's Lymphoma: yesterday, today, and tomorrow.
- Sirolimus in combination with cyclosporine or tacrolimus plus methotrexate for prevention of Graft-versus-host disease following hematopoietic cell transplantation fro...
- Simultaneously targeting CD45 significantly increases cytotoxicity of the anti-CD33 immunoconjugate, gemtuzumab ozogamicin, against Acute myeloid leukemia (AML) cells ...
- Impact of cytogenetics on the outcome of adult Acute lymphoblastic leukemia: results of Southwest Oncology Group 9400 study.
- Eradication of disseminated Leukemia in a syngeneic murine Leukemia model using pretargeted anti-CD45 radioimmunotherapy.
- Allogeneic hematopoietic cell transplantation for Acute myeloid leukemia when a matched related donor is not available.
- Indications for hematopoietic cell transplantation in Acute leukemia.
- Hematopoietic cell transplantation specific comorbidity index as an outcome predictor for patients with Acute myeloid leukemia in first remission: combined FHCRC and M...
- Phase II evaluation of an intensified induction therapy with standard daunomycin and cytarabine followed by high dose cytarabine for adults with previously untreated a...
- Hematopoietic-Cell transplantation at 50.
- Relationhip between event-free survival and overall survival in Acute myeloid leukemia: A report from SWOG, HOVN/SAKK, and MRC/NCRI.
Schools
Tufts University
University Of Mi Hosps and Health Ctrs
Procedures Preformed
- HPC Transplantation (Stem Cell Transplant)
- Thoracentesis
Conditions Treated
- Acute Leukemia
- Anemia
- Breast Cancer
- Carcinoma in Situ
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Doctors Specialties
- Medical Oncology
- Oncology
Accepted Insurances
Awards
- Fellow (FASCO)
Hospital
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UW Medicine/Harborview Medical Center -
Seattle Children's Hospital -
University of Washington Medical Center
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1356426183 |
| Last Name Of The Provider | APPELBAUM |
| First Name Of The Provider | FREDERICK |
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